ADAGE CAPITAL PARTNERS GP, L.L.C.

Position in PRAX — Praxis Precision Medicines, Inc.

CIK 1165408 Boston, MA

Position in PRAX

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$262,822,948

-$21,693,405 QoQ

Shares Held

815,739

-15.5% QoQ

Ownership

2.93%

of shares outstanding

% of Portfolio

0.42%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Dec 2023

10 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

ADAGE CAPITAL PARTNERS GP, L.L.C. holds $4,593,636,445 across 120 Biotechnology names. PRAX ranks #6 (5.7% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	RVMD	Revolution Medicines, Inc.	5,475,611	$532,503,169
2	RPRX	Royalty Pharma plc	7,480,633	$358,845,965
3	CNTA	Centessa Pharmaceuticals plc	8,925,010	$354,501,397
4	ROIV	Roivant Sciences Ltd.	12,794,097	$354,396,486
5	TNGX	Tango Therapeutics, Inc.	12,809,485	$267,974,426
6	PRAX	Praxis Precision Medicines, Inc. This page	815,739	$262,822,948
7	INSM	INSMED Inc	900,000	$147,168,000
8	AXSM	Axsome Therapeutics, Inc.	737,578	$124,665,433

10 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$262,822,948	815,739	-15.5%	Shares	Sole	2026-05-15
2025-12-31	$284,516,353	965,313	-59.3%	Shares	Sole	2026-02-17
2025-09-30	$125,826,505	2,374,085	+20.2%	Shares	Sole	2025-11-14
2025-06-30	$83,031,299	1,974,585	+13.3%	Shares	Sole	2025-08-14
2025-03-31	$65,998,245	1,742,758	+188.1%	Shares	Sole	2025-05-15
2024-12-31	$46,561,569	605,010	-29.2%	Shares	Sole	2025-02-14
2024-09-30	$49,143,935	854,083	-24.7%	Shares	Sole	2024-11-14
2024-06-30	$46,905,672	1,134,083	-18.6%	Shares	Sole	2024-08-14
2024-03-31	$85,002,568	1,393,028	+88.6%	Shares	Sole	2024-05-15
2023-12-31	$16,457,478	738,666	—	Shares	Sole	2024-02-14
No filing history on record for this holder in this stock.