Boxer Capital Management, LLC

CIK

2018299

Location

San Diego, CA

Portfolio Value

Small $753,318,362

Diversification

Diversified

Filing Date

Global Rank

#2,089 / 8,605 ▲ 791 · as of Mar 2026

Top Industry

Biotechnology 98.2%

3Y Alpha vs SPY

+109.5%

Period ended 3 months ago

Filed May 15, 2026 · 55d

6 quarters · since Dec 2024

Clone Performance

Feb 2025–Jul 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+217.2%

SPY

+24.4%

Annualised alpha

+111.7%

Max drawdown

−34.1%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

52 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

30.2%

+8.2 pts

Top 5

50.6%

+3.0 pts

Top 10

64.0%

−0.9 pts

HHI

1,111

Diversified+343

Portfolio Trend

6 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	99.7%	$750,964,214	51
Consumer Defensive	0.3%	$2,354,148	1

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

13 positions

Ticker	Company	Δ Shares	Shares	Value
PGEN	Precigen, Inc.	+2,125,000	3,500,000	$13,545,000
VIR	Vir Biotechnology, Inc.	+1,241,000	1,866,000	$16,719,360
ZURA	Zura Bio Ltd	+850,000	900,000	$5,355,000
REPL	Replimune Group, Inc.	+425,000	1,175,000	$8,988,750
QURE	uniQure N.V.	+372,000	662,000	$10,823,700
SRZN	Surrozen, Inc./DE	+350,168	766,318	$22,322,843
CLNN	Clene Inc.	+277,778	477,515	$2,354,148
CAPR	Capricor Therapeutics, Inc.	+265,000	590,000	$17,936,000
KOD	Kodiak Sciences Inc.	+225,000	1,361,000	$51,881,320
RVMD	Revolution Medicines, Inc.	+100,000	500,000	$48,625,000
ABVX	Abivax S.A.	+75,000	200,000	$22,270,000
KPTI	Karyopharm Therapeutics Inc.	+50,000	302,536	$1,685,125
AVTX	Avalo Therapeutics, Inc.	+25,000	300,000	$4,479,000
No positions match the current search.

Trimmed

Positions the filer reduced

3 positions

Ticker	Company	Δ Shares	Shares	Value
PEPG	PepGen Inc.	−101,000	272,892	$483,018
HELP	Cybin Inc.	−75,000	640,000	$3,072,000
INO	Inovio Pharmaceuticals, Inc.	−50,000	2,370,122	$4,124,012
No positions match the current search.

New Positions

Positions the filer opened this quarter

12 positions

Ticker	Company	Shares	Value
PCVX	Vaxcyte, Inc.	325,000	$18,885,750
CRVS	Corvus Pharmaceuticals, Inc.	1,100,000	$16,093,000
DFTX	Definium Therapeutics, Inc.	598,500	$11,311,650
IRD	Opus Genetics, Inc.	2,250,000	$10,237,500
CORT	Corcept Therapeutics Inc	250,000	$10,077,500
SLNO	Soleno Therapeutics Inc	200,000	$6,696,000
ALLO	Allogene Therapeutics, Inc.	2,725,000	$6,649,000
RLMD	Relmada Therapeutics, Inc.	842,106	$5,861,057
OCUL	Ocular Therapeutix, Inc	350,000	$2,964,500
ANTX	AN2 Therapeutics, Inc.	749,035	$2,561,699
ORIC	Oric Pharmaceuticals, Inc.	176,500	$2,236,255
RGNX	REGENXBIO Inc.	15,000	$125,700
No positions match the current search.

Sold Out

Positions the filer fully exited

1 positions

Ticker	Company	Shares	Value	Open
CBIO	Crescent Biopharma, Inc.	453,686	$5,380,715
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

52 positions · $753,318,362 total · as of Mar 31, 2026

All sectors Consumer Defensive Healthcare

Showing 1–50 of 52 positions by value · page 1 of 2

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
TNGX	Tango Therapeutics, Inc. Healthcare	Held	10,876,219	0	$227,530,501	+136.1%	30.20%
KOD	Kodiak Sciences Inc. Healthcare	Added	1,361,000	+225,000	$51,881,320	+63.3%	6.89%
RVMD	Revolution Medicines, Inc. Healthcare	Added	500,000	+100,000	$48,625,000	+52.6%	6.45%
KYMR	Kymera Therapeutics, Inc. Healthcare	Held	329,100	0	$27,410,739	+7.0%	3.64%
CELC	Celcuity Inc. Healthcare	Held	225,000	0	$25,681,500	+14.4%	3.41%
SRZN	Surrozen, Inc./DE Healthcare	Added	766,318	+350,168	$22,322,843	+137.4%	2.96%
ABVX	Abivax S.A. Healthcare	Added	200,000	+75,000	$22,270,000	+32.1%	2.96%
TERN	Terns Pharmaceuticals, Inc. Healthcare	Held	375,000	0	$19,770,000	+30.5%	2.62%
PCVX	Vaxcyte, Inc. Healthcare	NEW	325,000	NEW	$18,885,750	NEW	2.51%
CAPR	Capricor Therapeutics, Inc. Healthcare	Added	590,000	+265,000	$17,936,000	+91.2%	2.38%
PTGX	Protagonist Therapeutics, Inc Healthcare	Held	170,000	0	$17,918,000	+20.7%	2.38%
VIR	Vir Biotechnology, Inc. Healthcare	Added	1,866,000	+1,241,000	$16,719,360	+343.6%	2.22%
CRVS	Corvus Pharmaceuticals, Inc. Healthcare	NEW	1,100,000	NEW	$16,093,000	NEW	2.14%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Held	46,457	0	$14,967,980	+9.3%	1.99%
PTCT	Ptc Therapeutics, Inc. Healthcare	Held	200,000	0	$13,626,000	−10.3%	1.81%
PGEN	Precigen, Inc. Healthcare	Added	3,500,000	+2,125,000	$13,545,000	+135.7%	1.80%
DFTX	Definium Therapeutics, Inc. Healthcare	NEW	598,500	NEW	$11,311,650	NEW	1.50%
AMLX	Amylyx Pharmaceuticals, Inc. Healthcare	Held	800,000	0	$11,120,000	+15.1%	1.48%
QURE	uniQure N.V. Healthcare	Added	662,000	+372,000	$10,823,700	+56.0%	1.44%
IRD	Opus Genetics, Inc. Healthcare	NEW	2,250,000	NEW	$10,237,500	NEW	1.36%
CORT	Corcept Therapeutics Inc Healthcare	NEW	250,000	NEW	$10,077,500	NEW	1.34%
URGN	UroGen Pharma Ltd. Healthcare	Held	500,000	0	$8,990,000	−23.2%	1.19%
REPL	Replimune Group, Inc. Healthcare	Added	1,175,000	+425,000	$8,988,750	+23.3%	1.19%
COGT	Cogent Biosciences, Inc. Healthcare	Held	225,000	0	$8,660,250	+8.4%	1.15%
PALI	Palisade Bio, Inc. Healthcare	Held	4,799,875	0	$8,399,781	−25.5%	1.12%
SLNO	Soleno Therapeutics Inc Healthcare	NEW	200,000	NEW	$6,696,000	NEW	0.89%
ALLO	Allogene Therapeutics, Inc. Healthcare	NEW	2,725,000	NEW	$6,649,000	NEW	0.88%
CYTK	Cytokinetics Inc Healthcare	Held	100,000	0	$6,591,000	+3.7%	0.87%
CTNM	Contineum Therapeutics, Inc. Healthcare	Held	494,000	0	$6,451,640	+14.3%	0.86%
APGE	Apogee Therapeutics, Inc. Healthcare	Held	70,000	0	$5,891,900	+11.5%	0.78%
RLMD	Relmada Therapeutics, Inc. Healthcare	NEW	842,106	NEW	$5,861,057	NEW	0.78%
ZURA	Zura Bio Ltd Healthcare	Added	900,000	+850,000	$5,355,000	+1943.9%	0.71%
MLTX	MoonLake Immunotherapeutics Healthcare	Held	275,000	0	$5,126,000	+41.4%	0.68%
AVTX	Avalo Therapeutics, Inc. Healthcare	Added	300,000	+25,000	$4,479,000	−10.3%	0.59%
INO	Inovio Pharmaceuticals, Inc. Healthcare	Reduced	2,370,122	-50,000	$4,124,012	−2.1%	0.55%
GPCR	Structure Therapeutics Inc. Healthcare	Held	75,000	0	$3,615,000	−30.7%	0.48%
SRPT	Sarepta Therapeutics, Inc. Healthcare	Held	150,000	0	$3,264,000	+1.1%	0.43%
HELP	Cybin Inc. Healthcare	Reduced	640,000	-75,000	$3,072,000	−47.5%	0.41%
OCUL	Ocular Therapeutix, Inc Healthcare	NEW	350,000	NEW	$2,964,500	NEW	0.39%
ANTX	AN2 Therapeutics, Inc. Healthcare	NEW	749,035	NEW	$2,561,699	NEW	0.34%
CLNN	Clene Inc. Consumer Defensive	Added	477,515	+277,778	$2,354,148	+100.8%	0.31%
ORIC	Oric Pharmaceuticals, Inc. Healthcare	NEW	176,500	NEW	$2,236,255	NEW	0.30%
SLDB	Solid Biosciences Inc. Healthcare	Held	300,000	0	$2,160,000	+27.7%	0.29%
IVVD	Invivyd, Inc. Healthcare	Held	1,500,000	0	$1,950,000	−47.4%	0.26%
LBRX	Lb Pharmaceuticals Inc Healthcare	Held	70,000	0	$1,726,200	+10.8%	0.23%
KPTI	Karyopharm Therapeutics Inc. Healthcare	Added	302,536	+50,000	$1,685,125	−9.3%	0.22%
NRIX	Nurix Therapeutics, Inc. Healthcare	Held	100,000	0	$1,550,000	−18.3%	0.21%
UPB	Upstream Bio, Inc. Healthcare	Held	150,000	0	$1,350,000	−66.9%	0.18%
MIST	Milestone Pharmaceuticals Inc. Healthcare	Held	666,666	0	$793,332	−41.1%	0.11%
PEPG	PepGen Inc. Healthcare	Reduced	272,892	-101,000	$483,018	−80.2%	0.06%