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Definium Therapeutics, Inc.
$44.19 +0.79 (+1.82%) At close · Jul 2
Market Cap
$4.82B
Shares
109,066,783

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

The Jun 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out.
Holders: 250
Total Value: $1,493,886,733
Total Shares: 79,040,654
Showing 1–100 of 260 holdings by value · page 1 of 3

Institutional Ownership Trend

3 quarters

Holder Concentration

Across 249 13F filers
Top Holder
10.7%
Dec 2025 → Mar 2026 · range 10.7% – 58.1%
of institutional value
Top 5
32.8%
Dec 2025 → Mar 2026 · range 32.8% – 99.7%
of institutional value
Top 10
47.0%
Dec 2025 → Mar 2026 · range 47.0% – 100.0%
of institutional value
HHI
345
Dec 2025 → Mar 2026 · range 345 – 4,233
Broadly held
Showing 100 of 260
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega BlackRock, Inc. $160,276,343 10.73% 8,480,230
Large Driehaus Capital Management LLC $111,734,702 7.48% 5,911,889
Large Avoro Capital Advisors LLC $94,500,000 6.33% 5,000,000
Mega JANUS HENDERSON GROUP PLC $67,209,174 4.50% 3,556,041
Mid Deep Track Capital, LP $56,700,000 3.80% 3,000,000
Mega GEODE CAPITAL MANAGEMENT, LLC $47,163,040 3.16% 2,495,399
Mega STATE STREET CORP $46,718,399 3.13% 2,471,873
Small Octagon Capital Advisors LP $46,116,000 3.09% 2,440,000
Mid Commodore Capital LP $37,800,000 2.53% 2,000,000
Mega FMR LLC $34,201,628 2.29% 1,809,610
Small Trails Edge Capital Partners, LP $32,850,279 2.20% 1,738,110
Mega GOLDMAN SACHS GROUP INC $31,665,267 2.12% 1,675,411
Mid ArrowMark Colorado Holdings LLC $30,140,151 2.02% 1,594,717
Mega CITADEL ADVISORS LLC $25,202,053 1.69% 1,333,442
Mega WELLINGTON MANAGEMENT GROUP LLP $24,659,753 1.65% 1,304,749
Large Candriam S.C.A. $24,449,588 1.64% 1,293,629
Large Balyasny Asset Management L.P. $24,082,776 1.61% 1,274,221
Mega TWO SIGMA INVESTMENTS, LP $22,710,429 1.52% 1,201,610
Large MARSHALL WACE, LLP $22,695,592 1.52% 1,200,825
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $21,735,000 1.45% 1,150,000
Mega VANGUARD CAPITAL MANAGEMENT LLC $20,732,884 1.39% 1,096,978
Large Holocene Advisors, LP $20,638,176 1.38% 1,091,967
Small AWM Investment Company, Inc. $20,353,277 1.36% 1,076,893
Small Catalio Capital Management, LP $19,617,897 1.31% 1,037,984
Mega AMERIPRISE FINANCIAL INC $18,268,889 1.22% 966,608
Mid Siren, L.L.C. $17,378,417 1.16% 919,493
Mega MILLENNIUM MANAGEMENT LLC $16,006,334 1.07% 846,896
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $15,876,000 1.06% 840,000
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $15,284,713 1.02% 808,715
Mid ORBIMED ADVISORS LLC $15,195,600 1.02% 804,000
Mega NORTHERN TRUST CORP Bank $15,100,853 1.01% 798,987
Mega Bank of New York Mellon Corp Bank $14,230,222 0.95% 752,922
Large Woodline Partners LP $14,227,768 0.95% 752,792
Mega Nuveen, LLC $13,194,655 0.88% 698,130
Mid EVENTIDE ASSET MANAGEMENT, LLC $12,968,461 0.87% 686,162
Small Boxer Capital Management, LLC $11,311,650 0.76% 598,500
Mega VANGUARD FIDUCIARY TRUST CO Bank $10,885,209 0.73% 575,937
Large Ensign Peak Advisors, Inc $10,334,198 0.69% 546,783
Large Blackstone Inc. $9,613,825 0.64% 508,668
Mega UBS Group AG $9,336,164 0.62% 493,977
Mega MORGAN STANLEY $8,289,025 0.55% 438,573
Large Qube Research & Technologies Ltd $8,052,439 0.54% 426,055
Mega DEUTSCHE BANK AG\ Bank $7,783,661 0.52% 411,834
Mid Integral Health Asset Management, LLC $7,560,000 0.51% 400,000
Small Tri Locum Partners LP $6,985,213 0.47% 369,588
Small SUPERSTRING CAPITAL MANAGEMENT LP $6,642,612 0.44% 351,461
Mid Sofinnova Investments, Inc. $6,504,737 0.44% 344,166
Small Patient Square Capital LP $6,255,900 0.42% 331,000
Small STEMPOINT CAPITAL LP $6,151,628 0.41% 325,483
Large RTW INVESTMENTS, LP $5,670,000 0.38% 300,000
Small SILVERBACK ASSET MANAGEMENT LLC $5,564,160 0.37% 294,400
Mid BIT Capital GmbH $5,244,957 0.35% 277,511
Mega D. E. Shaw & Co., Inc. $5,135,451 0.34% 271,717
Mega JPMORGAN CHASE & CO $4,999,899 0.33% 264,545
Mega JANE STREET GROUP, LLC $4,918,554 0.33% 260,241
Mid ROYCE & ASSOCIATES LP $4,423,563 0.30% 234,051
Mid SEVEN GRAND MANAGERS, LLC $4,252,500 0.28% 225,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $4,086,180 0.27% 216,200
Large Caption Management, LLC $4,008,690 0.27% 212,100
Mid Brevan Howard Capital Management LP $3,997,123 0.27% 211,488
Small PFM Health Sciences, LP $3,880,491 0.26% 205,317
Small Tetragon Partners GP Ltd $3,779,886 0.25% 199,994
Small HighVista Strategies LLC $3,512,678 0.24% 185,856
Large Point72 Asset Management, L.P. $3,316,761 0.22% 175,490
Mid Eversept Partners, LP $3,037,664 0.20% 160,723
Mega Swiss National Bank Bank $2,993,760 0.20% 158,400
Mega BANK OF AMERICA CORP /DE/ Bank $2,992,720 0.20% 158,345
Small Soviero Asset Management, LP $2,646,000 0.18% 140,000
Mega NEUBERGER BERMAN GROUP LLC $2,520,673 0.17% 133,369
Large Squarepoint Ops LLC $2,372,365 0.16% 125,522
Small Rosalind Advisors, Inc. $2,362,500 0.16% 125,000
Mega RHUMBLINE ADVISERS $2,267,470 0.15% 119,972
Large Russell Investments Group, Ltd. $2,257,868 0.15% 119,464
Large ExodusPoint Capital Management, LP $1,982,893 0.13% 104,915
Micro Data Collective IV GP, LLC $1,896,615 0.13% 100,350
Mid Burkehill Global Management, LP $1,890,000 0.13% 100,000
Small Seven Fleet Capital Management LP $1,887,864 0.13% 99,887
Mega ROYAL BANK OF CANADA Bank $1,836,928 0.12% 97,192
Large FRED ALGER MANAGEMENT, LLC $1,741,918 0.12% 92,165
Mega ALLIANCEBERNSTEIN L.P. $1,733,186 0.12% 91,703
Small AdvisorShares Investments LLC $1,725,588 0.12% 91,301
Large HRT FINANCIAL LP $1,684,764 0.11% 89,141
Mega Invesco Ltd. $1,665,485 0.11% 88,121
Mid GROUP ONE TRADING LLC $1,660,024 0.11% 87,832
Mega CITADEL ADVISORS LLC $1,619,730 0.11% 85,700
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,539,518 0.10% 81,456
Mega LPL Financial LLC $1,479,321 0.10% 78,271
Mega CITADEL ADVISORS LLC $1,324,890 0.09% 70,100
Mega PRICE T ROWE ASSOCIATES INC /MD/ $1,323,018 0.09% 70,001
Small PLATINUM INVESTMENT MANAGEMENT LTD $1,323,000 0.09% 70,000
Mega Legal & General Group Plc $1,130,199 0.08% 59,799
Mid Ikarian Capital, LLC $1,111,376 0.07% 58,803
Mega AQR CAPITAL MANAGEMENT LLC $1,079,075 0.07% 57,094
Large Rockefeller Capital Management L.P. $1,043,393 0.07% 55,206
Large MetLife Investment Management, LLC $1,025,532 0.07% 54,261
Mega VANGUARD ASSET MANAGEMENT, Ltd $1,020,940 0.07% 54,018
Large BLAIR WILLIAM & CO/IL $1,014,835 0.07% 53,695
Mega JANE STREET GROUP, LLC $996,030 0.07% 52,700
Mid KESTRA PRIVATE WEALTH SERVICES, LLC $956,113 0.06% 50,588
Large STATE OF WISCONSIN INVESTMENT BOARD $952,938 0.06% 50,420
Key facts CIK 1813814 CUSIP 24477V105 13F (30d) 2 filings 2 filers Visit website Investor relations

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