APGE · Apogee Therapeutics, Inc.

$134.72 +0.15 (+0.11%)

Market Cap

$10.19B

75.69M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 289

Total Value: $9,115,023,255

Total Shares: 68,673,433

Institutional Ownership Trend

12 quarters

Superinvestors Holding APGE

All superinvestors →

George Soros $74,926,085 Mario Gabelli $1,128,205

Holder Concentration

Across 289 13F filers · Δ vs Mar 31, 2026

Top Holder

12.4%

−0.5 pts

Top 5

31.9%

−13.6 pts

Top 10

45.8%

−14.3 pts

HHI

359

Broadly held−184

Quarterly Activity

vs Mar 31, 2026

New

114

Increased

Decreased

Sold Out

Unchanged

Holder count: +59

Institutional value: +34.9%

Shares held: -14.5%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large Balyasny Asset Management L.P.	+1,726,448	2,165,102
Mega BlackRock, Inc.	+1,421,381	5,507,032
Mega MILLENNIUM MANAGEMENT LLC	+1,408,912	1,501,504
Mega VANGUARD PORTFOLIO MANAGEMENT LLC	+1,132,420	1,528,750
Mega GOLDMAN SACHS GROUP INC	+1,040,751	1,693,341

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega T. Rowe Price Investment Management, Inc.	−9,538,801	762,183
Mega FMR LLC	−6,769,154	2,493,137
Mega WELLINGTON MANAGEMENT GROUP LLP	−3,811,377	564,326
Mega UBS Group AG	−942,497	201,831
Mega PRICE T ROWE ASSOCIATES INC /MD/	−905,942	237,210

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mid HBK INVESTMENTS L P	2,850,000	$378,280,500
Mid GLAZER CAPITAL, LLC	1,641,042	$217,815,504
Large Pentwater Capital Management LP	1,425,000	$189,140,250
Mega Jupiter Topco LLC	1,193,626	$158,429,978
Mid Kryger Capital LLC	742,555	$98,559,325

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Large RTW INVESTMENTS, LP	2,782,097	$234,169,104
Mega JANUS HENDERSON GROUP PLC	2,360,596	$198,691,364
Mid Vestal Point Capital, LP	1,100,000	$92,587,000
Large Polar Capital Holdings Plc	539,177	$45,382,528
Mid BRAIDWELL LP	478,667	$40,289,401

Filter: New 114 Increased 85 Reduced 69 Sold out 55 Unchanged 21

Showing 100 of 305

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Venrock Adviser, LLC

$1,127,318,496

12.37%

8,493,321

BlackRock, Inc.

$730,948,348

8.02%

5,507,032

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	157,569	$20,914,133	2.9%	Sole
BlackRock Investment Management (Australia) Ltd	94	$12,476	0.0%	Sole
BlackRock Asset Management Canada Ltd	5,790	$768,506	0.1%	Sole
BlackRock Investment Management, LLC	141,072	$18,724,486	2.6%	Sole
BLACKROCK ADVISORS LLC	1,063,567	$141,167,247	19.3%	Sole
BlackRock Fund Advisors	2,144,605	$284,653,421	38.9%	Sole
BlackRock Institutional Trust Company, N.A.	1,533,445	$203,534,154	27.8%	Sole
BlackRock Japan Co. Ltd	815	$108,174	0.0%	Sole
BlackRock Fund Managers Ltd.	7,300	$968,929	0.1%	Sole
BlackRock Investment Management (UK) Ltd.	29,878	$3,965,706	0.5%	Sole
BlackRock (Netherlands) B.V.	199	$26,413	0.0%	Sole
BlackRock Asset Management Ireland Ltd	85,813	$11,389,959	1.6%	Sole
BlackRock (Luxembourg) S.A.	295,905	$39,275,470	5.4%	Sole
BlackRock Asset Management Schweiz AG	6,375	$846,153	0.1%	Sole
Aperio Group, LLC	34,603	$4,592,856	0.6%	Sole
SpiderRock Advisors, LLC	2	$265	0.0%	Sole

HBK INVESTMENTS L P

$378,280,500

4.15%

2,850,000

VANGUARD CAPITAL MANAGEMENT LLC

$341,397,354

3.75%

2,572,119

FMR LLC

$330,914,071

3.63%

2,493,137

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	1,819,226	$241,465,866	73.0%	Defined
FIDELITY MANAGEMENT TRUST CO	427,685	$56,766,630	17.2%	Defined
STRATEGIC ADVISERS LLC	1,540	$204,404	0.1%	Defined
FIAM LLC	7,867	$1,044,186	0.3%	Defined
Fidelity Diversifying Solutions LLC	236,819	$31,432,985	9.5%	Defined

STATE STREET CORP

$304,979,428

3.35%

2,297,743

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	2,297,743	$304,979,428	100.0%	Defined

Driehaus Capital Management LLC

$230,963,605

2.53%

1,740,101

GOLDMAN SACHS GROUP INC

$224,757,150

2.47%

1,693,341

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	1,516,757	$201,319,156	89.6%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	174,484	$23,159,261	10.3%	Defined
Goldman Sachs Trust Company, N.A.	2,100	$278,733	0.1%	Defined

Balyasny Asset Management L.P.

$221,008,988

2.42%

1,665,102

GLAZER CAPITAL, LLC

$217,815,504

2.39%

1,641,042

Paradigm Biocapital Advisors LP

$209,233,581

2.30%

1,576,385

VANGUARD PORTFOLIO MANAGEMENT LLC

$202,910,987

2.23%

1,528,750

MILLENNIUM MANAGEMENT LLC

$197,954,052

2.17%

1,491,404

Pentwater Capital Management LP

$189,140,250

2.08%

1,425,000

MORGAN STANLEY

$188,699,716

2.07%

1,421,681

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	444	$58,932	0.0%	Defined
MORGAN STANLEY & CO. LLC	16,161	$2,145,049	1.1%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	1,383,997	$183,697,921	97.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	109	$14,467	0.0%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	20,970	$2,783,347	1.5%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$174,522,429

1.91%

1,314,868

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	190,569	$25,294,223	14.5%	Defined
Held directly	1,124,299	$149,228,206	85.5%	Defined

PERCEPTIVE ADVISORS LLC

$173,625,838

1.90%

1,308,113

Jupiter Topco LLC

$158,429,978

1.74%

1,193,626

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	127,880	$16,973,512	10.7%	Defined
JANUS HENDERSON INVESTORS US LLC	1,065,746	$141,456,466	89.3%	Defined

BANK OF AMERICA CORP /DE/

$149,472,427

1.64%

1,126,139

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	577,834	$76,695,906	51.3%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	3,033	$402,570	0.3%	Defined
BOFA SECURITIES, INC.	543,320	$72,114,863	48.2%	Defined
MANAGED ACCOUNT ADVISORS LLC	1,952	$259,088	0.2%	Defined

Affinity Asset Advisors, LLC

$131,004,510

1.44%

987,000

MERCER GLOBAL ADVISORS INC /ADV

$124,936,492

1.37%

941,283

First Light Asset Management, LLC

$123,477,258

1.35%

930,289

ALLIANCEBERNSTEIN L.P.

$102,873,448

1.13%

775,058

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	775,058	$102,873,448	100.0%	Defined

T. Rowe Price Investment Management, Inc.

$101,164,549

1.11%

762,183

Kryger Capital LLC

$98,559,325

1.08%

742,555

Qube Research & Technologies Ltd

$87,559,060

0.96%

659,678

First Trust Capital Management L.P.

$82,980,406

0.91%

625,182

Remedium Capital Partners, LLC

$77,871,496

0.85%

586,691

SOROS FUND MANAGEMENT LLC

$74,926,085

0.82%

564,500

WELLINGTON MANAGEMENT GROUP LLP

$74,902,987

0.82%

564,326

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	363,628	$48,264,344	64.4%	Defined
Wellington Managment Canada LLC	20,114	$2,669,731	3.6%	Defined
Wellington Management Singapore Pte. Ltd.	22,504	$2,986,955	4.0%	Defined
Wellington Management International Ltd	17,317	$2,298,485	3.1%	Defined
Wellington Trust Company, NA joint	137,658	$18,271,346	24.4%	Defined
Wellington Management Australia Pty Ltd	2,070	$274,751	0.4%	Defined
Wellington Management Europe GmbH	1,035	$137,375	0.2%	Defined

Balyasny Asset Management L.P.

$66,365,000

0.73%

500,000

Woodline Partners LP

$61,669,278

0.68%

464,622

WHITEBOX ADVISORS LLC

$59,728,632

0.66%

450,001

NORTHERN TRUST CORP

$59,085,289

0.65%

445,154

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	409,943	$54,411,734	92.1%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	28,212	$3,744,578	6.3%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	6,999	$928,977	1.6%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$58,886,726

0.65%

443,658

AQR Arbitrage LLC

$57,060,627

0.63%

429,900

Magnetar Financial LLC

$52,975,594

0.58%

399,123

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Magnetar Asset Management LLC	124,108	$16,472,854	31.1%	Sole
Held directly	275,015	$36,502,740	68.9%	Sole

Man Group plc

$52,693,809

0.58%

397,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GLG LLC	260,320	$34,552,273	65.6%	Defined
GLG Partners LP	136,680	$18,141,536	34.4%	Defined

VANGUARD FIDUCIARY TRUST CO

$52,186,781

0.57%

393,180

Opaleye Management Inc.

$51,764,700

0.57%

390,000

TIG Advisors, LLC

$48,346,902

0.53%

364,250

FRANKLIN RESOURCES INC

$48,231,292

0.53%

363,379

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fiduciary Trust International of the South	14	$1,858	0.0%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	54	$7,167	0.0%	Defined
FRANKLIN ADVISERS INC	22,889	$3,038,056	6.3%	Defined
PUTNAM INVESTMENT MANAGEMENT LLC	245,863	$32,633,395	67.7%	Defined
PUTNAM ADVISORY CO LLC	94,559	$12,550,816	26.0%	Defined

JPMORGAN CHASE & CO

$47,683,248

0.52%

359,250

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Trust Co of Delaware	225	$29,863	0.1%	Defined
JPMorgan Chase Bank, N.A.	270,879	$35,953,769	75.4%	Defined
J.P. Morgan Investment Management Inc.	35,477	$4,708,862	9.9%	Defined
J.P. Morgan Securities LLC	46,901	$6,225,169	13.1%	Defined
55I, LLC	11	$1,460	0.0%	Defined
J.P. Morgan Markets Ltd	4,768	$632,856	1.3%	Defined
J.P. MORGAN MANSART MANAGEMENT Ltd	989	$131,269	0.3%	Defined

Cinctive Capital Management LP

$46,477,400

0.51%

350,165

LOOMIS SAYLES & CO L P

$44,950,871

0.49%

338,664

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
LOOMIS SAYLES TRUST COMPANY, LLC	57,056	$7,573,042	16.8%	Defined
Held directly	281,608	$37,377,829	83.2%	Defined

Polar Asset Management Partners Inc.

$42,801,044

0.47%

322,467

FRONTIER CAPITAL MANAGEMENT CO LLC

$40,315,277

0.44%

303,739

NEXPOINT ASSET MANAGEMENT, L.P.

$39,811,035

0.44%

299,940

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NexPoint Advisors, L.P.	7,510	$996,802	2.5%	Other
Held directly	292,430	$38,814,233	97.5%	Sole

Fairmount Funds Management LLC

$39,639,416

0.43%

298,647

Squarepoint Ops LLC

$38,586,336

0.42%

290,713

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	290,713	$38,586,336	100.0%	Defined

CITIGROUP INC

$38,420,556

0.42%

289,464

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	289,464	$38,420,556	100.0%	Defined

Slotnik Capital, LLC

$34,608,020

0.38%

260,740

EVENTIDE ASSET MANAGEMENT, LLC

$34,509,800

0.38%

260,000

ADAGE CAPITAL PARTNERS GP, L.L.C.

$33,182,500

0.36%

250,000

D. E. Shaw & Co., Inc.

$32,662,994

0.36%

246,086

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	241,903	$32,107,785	98.3%	Defined
D. E. Shaw Investment Management, L.L.C. joint	4,183	$555,209	1.7%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$31,484,883

0.35%

237,210

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	74,325	$9,865,157	31.3%	Defined
Held directly	162,885	$21,619,726	68.7%	Sole

BNP PARIBAS ARBITRAGE, SA

$27,901,438

0.31%

210,212

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$26,917,644

0.30%

202,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	202,800	$26,917,644	100.0%	Other

UBS Group AG

$26,789,027

0.29%

201,831

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	1,496	$198,564	0.7%	Defined
UBS AG	152,309	$20,215,973	75.5%	Defined
UBS Securities LLC	48,026	$6,374,490	23.8%	Defined

PICTON MAHONEY ASSET MANAGEMENT

$26,546,000

0.29%

200,000

MUFG Securities EMEA plc

$23,957,765

0.26%

180,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MUFG Bank, Ltd. joint	180,500	$23,957,765	100.0%	Defined

Allianz Asset Management GmbH

$23,825,035

0.26%

179,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Pacific Investment Management Company LLC	177,000	$23,493,210	98.6%	Defined
Allianz Global Invesstors Taiwan Ltd.	2,500	$331,825	1.4%	Defined

PICTON MAHONEY ASSET MANAGEMENT

$21,900,450

0.24%

165,000

Verition Fund Management LLC

$21,138,048

0.23%

159,256

HIGHBRIDGE CAPITAL MANAGEMENT LLC

$20,686,899

0.23%

155,857

Sagefield Capital LP

$20,591,067

0.23%

155,135

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sagefield Investment Group, LP	135,394	$17,970,845	87.3%	Other
Held directly	19,741	$2,620,222	12.7%	Sole

Bank of New York Mellon Corp

$20,283,131

0.22%

152,815

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware joint	95	$12,609	0.1%	Defined
Mellon Investments Corporation joint	62,196	$8,255,274	40.7%	Defined
The Bank of New York Mellon	84,282	$11,186,749	55.2%	Defined
BNY Mellon, NA joint	6,240	$828,234	4.1%	Defined
Held directly	2	$265	0.0%	Defined

RENAISSANCE TECHNOLOGIES LLC

$19,484,764

0.21%

146,800

First Turn Management, LLC

$18,425,844

0.20%

138,822

Grantham, Mayo, Van Otterloo & Co. LLC

$18,236,438

0.20%

137,395

Nuveen, LLC

$17,471,779

0.19%

131,634

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	4,497	$596,886	3.4%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	34,778	$4,616,083	26.4%	Defined
TEACHERS ADVISORS, LLC joint	92,359	$12,258,810	70.2%	Defined

GABELLI FUNDS LLC

$16,894,007

0.19%

127,281

Universal- Beteiligungs- und Servicegesellschaft mbH

$16,094,574

0.18%

121,258

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH joint	121,258	$16,094,574	100.0%	Defined

CAPSTONE INVESTMENT ADVISORS, LLC

$15,927,600

0.17%

120,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Capstone Investment Advisors (UK), LLP	120,000	$15,927,600	100.0%	Defined

Twin Securities, Inc.

$15,927,600

0.17%

120,000

Melqart Asset Management (UK) Ltd

$15,562,459

0.17%

117,249

Caption Management, LLC

$15,356,861

0.17%

115,700

Maven Securities LTD

$15,266,339

0.17%

115,018

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Maven Investment Partners Ltd	24,000	$3,185,520	20.9%	Defined
Maven Investment Partners US Ltd	91,018	$12,080,819	79.1%	Defined

TUDOR INVESTMENT CORP ET AL

$13,352,638

0.15%

100,600

SEVEN GRAND MANAGERS, LLC

$13,273,000

0.15%

100,000

DEUTSCHE BANK AG\

$13,137,482

0.14%

98,979

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS Investment GmbH	52,877	$7,018,364	53.4%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	847	$112,422	0.9%	Defined
DWS Investments UK Ltd	45,255	$6,006,696	45.7%	Defined

Chicago Capital Management, LLC

$12,888,083

0.14%

97,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PRELUDE CAPITAL MANAGEMENT, LLC	97,100	$12,888,083	100.0%	Other

WATER ISLAND CAPITAL LLC

$12,596,077

0.14%

94,900

TWO SIGMA INVESTMENTS, LP

$12,577,362

0.14%

94,759

VICTORY CAPITAL MANAGEMENT INC

$11,674,001

0.13%

87,953

ExodusPoint Capital Management, LP

$11,613,875

0.13%

87,500

Handelsbanken Fonder AB

$11,454,599

0.13%

86,300

GABELLI & Co INVESTMENT ADVISERS, INC.

$10,836,740

0.12%

81,645

GARDNER LEWIS ASSET MANAGEMENT L P

$10,618,400

0.12%

80,000

Candriam S.C.A.

$10,576,457

0.12%

79,684

HARVEST MANAGEMENT LLC

$10,485,670

0.12%

79,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BOHRER NATHANIEL joint	79,000	$10,485,670	100.0%	Other

MARSHALL WACE, LLP

$10,283,256

0.11%

77,475

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	77,475	$10,283,256	100.0%	Other

Swiss National Bank

$10,180,391

0.11%

76,700

PRUDENTIAL FINANCIAL INC

$10,169,772

0.11%

76,620

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PGIM Quantitative Solutions LLC	64,120	$8,510,647	83.7%	Defined
Prudential Trust Co	12,500	$1,659,125	16.3%	Defined

WCM INVESTMENT MANAGEMENT, LLC

$10,084,029

0.11%

75,974

Alberta Investment Management Corp

$9,954,750

0.11%

75,000

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$9,768,928

0.11%

73,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	73,600	$9,768,928	100.0%	Other

Westchester Capital Management, LLC

$9,684,245

0.11%

72,962

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WESTCHESTER CAPITAL PARTNERS, LLC	910	$120,784	1.2%	Sole
Virtus Investment Advisers, LLC	62,182	$8,253,416	85.2%	Other
Held directly	9,870	$1,310,045	13.5%	Sole

Boxer Capital Management, LLC

$9,291,100

0.10%

70,000

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$8,817,648

0.10%

66,433

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	615	$81,628	0.9%	Defined
UBS Asset Management Switzerland AG	49,450	$6,563,498	74.4%	Sole
UBS Asset Management (UK) Ltd.	4,989	$662,188	7.5%	Other
Held directly	11,379	$1,510,334	17.1%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Caisse Federale de Credit Mutuel	63,424	$8,418,267	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ABC ARBITRAGE ASSET MANAGEMENT	52,918	$7,023,806	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMO Bank N.A.	321	$42,606	0.6%	Defined
BMO CAPITAL MARKETS CORP.	50,000	$6,636,500	99.4%	Defined
BMO NESBITT BURNS INC.	3	$398	0.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wabon Partners, L.P.	1,461	$193,918	3.1%	Sole
Held directly	45,000	$5,972,850	96.9%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	42,117	$5,590,189	91.9%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	1,063	$141,091	2.3%	Defined
WELLS FARGO CLEARING SERVICES, LLC	2,643	$350,805	5.8%	Defined
WELLS FARGO INVESTMENT INSTITUTE, INC.	23	$3,052	0.1%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Capula Investment US LP	45,000	$5,972,850	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	43,857	$5,821,139	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	6,936	$920,614	17.6%	Defined
Invesco Trust Co joint	17,993	$2,388,210	45.8%	Defined
Invesco Capital Management LLC	14,388	$1,909,719	36.6%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
KBC Bank NV joint	38,496	$5,109,574	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Newfound Research LLC	35,113	$4,660,548	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	33,559	$4,454,286	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	29,051	$3,855,939	88.2%	Defined
Global X Management (AUS) Ltd joint	3,876	$514,461	11.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	4,378	$581,091	13.4%	Defined
Legal & General Investment Management Ltd joint	28,317	$3,758,514	86.6%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	31,856	$4,228,246	97.5%	Defined
Russell Investments Capital, LLC	831	$110,298	2.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	30,476	$4,045,079	99.5%	Sole
Schroder Investment Management North America Inc.	160	$21,236	0.5%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Virtu Americas LLC	29,790	$3,954,026	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	29,500	$3,915,535	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	27,256	$3,617,688	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TOKIO MARINE HOLDINGS, INC.	27,039	$3,588,886	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	26,800	$3,557,164	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	26,281	$3,488,277	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fifth Third Bank, National Association	25,914	$3,439,565	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ANGELO GORDON & CO., L.P.	25,000	$3,318,250	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	20,666	$2,742,998	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	18,846	$2,501,429	94.1%	Defined
BARCLAYS CAPITAL INC.	1,185	$157,285	5.9%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	293	$38,889	1.6%	Defined
Held directly	17,502	$2,323,040	98.4%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	16,908	$2,244,198	99.0%	Defined
FEDERATED MDTA LLC	173	$22,962	1.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	15,490	$2,055,987	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GUGGENHEIM FUNDS DISTRIBUTORS, LLC	414	$54,950	2.8%	Defined
SECURITY INVESTORS LLC	14,369	$1,907,197	97.2%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	13,302	$1,765,574	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Blackstone Alternative Asset Management L.P.	12,090	$1,604,705	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Metzler Asset Management GmbH	11,693	$1,552,011	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wolverine Holdings, LLC	10,909	$1,447,951	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	142	$18,847	1.6%	Sole
SEI TRUST CO	8,881	$1,178,775	98.4%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	8,555	$1,135,505	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	8,000	$1,061,840	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
KEB ASSET MANAGEMENT, LLC	2	$265	0.0%	Other
Arax Advisory Partners	37	$4,911	0.5%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	10	$1,327	0.1%	Other
Held directly	7,909	$1,049,761	99.4%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	7,553	$1,002,509	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	7,265	$964,283	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	7,000	$929,110	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	6,302	$836,464	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MITSUBISHI UFJ FINANCIAL GROUP INC	4,500	$597,285	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	4,093	$543,263	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Global Trading, LLC	3,245	$430,708	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Blue Trust, Inc.	2,670	$354,389	84.8%	Defined
Held directly	478	$63,444	15.2%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	1,372	$182,105	44.6%	Defined
RBC Capital Markets, LLC	1,650	$219,004	53.7%	Defined
RBC Rochdale, LLC	8	$1,061	0.3%	Defined
Held directly	44	$5,840	1.4%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ALLSTATE INVESTMENTS LLC	2,636	$349,876	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CIBC Private Wealth Advisors, Inc.	4	$530	0.2%	Defined
CIBC National Trust Co	1	$132	0.0%	Defined
CIBC WORLD MARKETS CORP	2,490	$330,497	99.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jump Trading Holdings, LLC	2,343	$310,986	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Strive Asset Management, LLC	2,065	$274,087	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	1,834	$243,426	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	1,701	$225,773	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manufacturers & Traders Trust Company joint	94	$12,476	6.0%	Defined
Wilmington Trust Investment Advisors, Inc. joint	24	$3,185	1.5%	Defined
Wilmington Trust National Association joint	1,436	$190,599	92.1%	Defined
Wilmington Trust Company	6	$796	0.4%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nykredit Bank A/S	1,308	$173,610	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER & CO. LLC	137	$18,184	15.4%	Defined
ROCKEFELLER TRUST COMPANY, N.A.	550	$73,001	62.0%	Defined
ROCKEFELLER FINANCIAL LLC	200	$26,546	22.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	385	$51,101	54.5%	Defined
Osaic Advisory Services, LLC	321	$42,606	45.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNP PARIBAS ASSET MANAGEMENT Europe	567	$75,257	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	526	$69,814	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wolverine Holdings, LLC	500	$66,365	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BESSEMER TRUST CO	215	$28,536	68.5%	Other
BESSEMER TRUST Co NATIONAL ASSOCIATION	99	$13,140	31.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Optiver VOF	242	$32,120	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMSS Wesson Wealth Solutions, LLC	145	$19,245	71.4%	Sole
Held directly	58	$7,695	28.6%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	190	$25,218	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIL Investments International	105	$13,936	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TORONTO DOMINION BANK	18	$2,389	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	22,968	$1,933,216	1.0%	Defined
JANUS HENDERSON INVESTORS US LLC	2,337,628	$196,758,148	99.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	539,177	$45,382,528	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JAY JEFFREY R joint	374,000	$31,479,580	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	348,674	$29,347,890	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	143,379	$12,068,210	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA SECURITIES INTERNATIONAL INC	88,561	$7,454,179	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA SECURITIES INTERNATIONAL INC	26,600	$2,238,922	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA SECURITIES INTERNATIONAL INC	18,200	$1,531,894	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
VOYA INVESTMENTS, LLC	15,000	$1,262,550	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLINGTON SMALL CAP EQUITY	12,844	$1,081,079	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Allspring Funds Management, LLC reporting on behalf of Morgan Stanley Smith Barney, LLC	84	$7,070	1.4%	Defined
Allspring Global Investments, LLC	5,968	$502,326	98.6%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Hudson Bay Capital UK LLP	5,720	$481,452	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Arrowpoint Investment Partners (Hong Kong) Ltd	4,007	$337,269	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STIFEL NICOLAUS & CO INC \MO\	2,785	$234,413	99.0%	Defined
Held directly	29	$2,440	1.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PARAMETRIC PORTFOLIO ASSOCIATES LLC	69	$5,807	100.0%	Other

Key facts CIK 1974640 CUSIP 03770N101 13F (30d) 283 filings 281 filers Visit website Investor relations