Position in APGE
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$12,577,362
-$11,106,897 QoQ
Shares Held
94,759
-66.3% QoQ
Ownership
0.125%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#79
of 285 holders
Holding Since
Dec 2023
11 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in APGE Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,273,657,992 across 342 Biotechnology names. APGE ranks #75 (0.2% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in APGE
Export CSV
11 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $12,577,362 | 94,759 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $23,684,259 | 281,386 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $7,943,590 | 105,241 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $4,861,958 | 122,375 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $5,024,590 | 115,694 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $9,419,763 | 252,135 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $12,071,634 | 266,482 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $11,707,351 | 199,308 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $11,892,435 | 302,222 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $5,945,946 | 89,480 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $699,589 | 25,039 | Shares | Sole | 2024-02-14 | |
| No filing history on record for this holder in this stock. | ||||||