Position in MRNA
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$461,589,323
+$245,070,912 QoQ
Shares Held
9,086,404
+23.8% QoQ
Ownership
2.29%
of shares outstanding
% of Portfolio
0.42%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2020
17 quarters on record
Voting authority
Sole 97.38180252605981.ToString("F0")%
Shared 0.ToString("F0")%
None 2.618197473940186.ToString("F0")%
Common Shares in MRNA Over Time
Shares Held
Position Value (USD)
Derivatives in MRNA
reported options exposure · as of Mar 31, 2026CallValue
$2,824,480
CallShares
55,600
PutValue
$3,302,000
PutShares
65,000
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,502,861,072 across 315 Biotechnology names. MRNA ranks #3 (8.4% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
This page
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in MRNA
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30 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $2,824,480 | 55,600 | Call | Sole | 2026-05-15 | |
| 2026-03-31 | $3,302,000 | 65,000 | Put | Sole | 2026-05-15 | |
| 2026-03-31 | $461,589,323 | 9,086,404 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $216,518,411 | 7,342,096 | Shares | Sole | 2026-02-17 | |
| 2025-12-31 | $256,563 | 8,700 | Put | Sole | 2026-02-17 | |
| 2025-12-31 | $353,880 | 12,000 | Call | Sole | 2026-02-17 | |
| 2025-09-30 | $284,130 | 11,000 | Put | Sole | 2025-11-14 | |
| 2025-09-30 | $194,499,409 | 7,529,981 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $192,004,548 | 6,959,208 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $126,273,820 | 4,454,103 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $27,610,783 | 664,040 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $41,934,622 | 627,482 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $2,301,018 | 19,377 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $2,064,813 | 19,377 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $1,927,042 | 19,377 | Shares | Sole | 2024-02-14 | |
| 2023-06-30 | $78,257,907 | 644,098 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $2,627,293 | 17,107 | Shares | Sole | 2023-05-15 | |
| 2021-12-31 | $17,702,406 | 69,700 | Call | Sole | 2022-02-14 | |
| 2021-12-31 | $19,099,296 | 75,200 | Put | Sole | 2022-02-14 | |
| 2021-12-31 | $72,107,969 | 283,912 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $193,150,073 | 501,871 | Shares | Sole | 2021-11-15 | |
| 2021-09-30 | $29,865,136 | 77,600 | Put | Sole | 2021-11-15 | |
| 2021-09-30 | $25,670,162 | 66,700 | Call | Sole | 2021-11-15 | |
| 2021-06-30 | $27,445,664 | 116,800 | Put | Sole | 2021-08-16 | |
| 2021-06-30 | $200,370,970 | 852,715 | Shares | Sole | 2021-08-16 | |
| 2021-06-30 | $20,231,778 | 86,100 | Call | Sole | 2021-08-16 | |
| 2021-03-31 | $7,004,122 | 53,487 | Shares | Sole | 2021-05-17 | |
| 2021-03-31 | $22,130,550 | 169,000 | Call | Sole | 2021-05-17 | |
| 2021-03-31 | $22,182,930 | 169,400 | Put | Sole | 2021-05-17 | |
| 2020-12-31 | $84,888,561 | 812,564 | Shares | Sole | 2021-02-16 | |
| No filing history on record for this holder in this stock. | ||||||