Position in BBIO
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$351,708,338
+$119,970,280 QoQ
Shares Held
4,722,185
+51.3% QoQ
Ownership
2.42%
of shares outstanding
% of Portfolio
0.29%
of 13F equity value
Holder Rank
#9
of 473 holders
Holding Since
Sep 2020
24 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in BBIO Over Time
Shares Held
Position Value (USD)
Derivatives in BBIO
reported options exposure · as of Jun 30, 2026CallValue
$744,800
CallShares
10,000
PutValue
$975,688
PutShares
13,100
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. BBIO ranks #5 (4.8% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
This page
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in BBIO
Export CSV
26 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $975,688 | 13,100 | Put | Sole | 2026-08-14 | |
| 2026-06-30 | $351,708,338 | 4,722,185 | Shares | Sole | 2026-08-14 | |
| 2026-06-30 | $744,800 | 10,000 | Call | Sole | 2026-08-14 | |
| 2026-03-31 | $231,738,058 | 3,120,631 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $148,929,625 | 1,947,047 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $120,965,195 | 2,328,941 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $101,000,913 | 2,339,067 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $29,153,606 | 843,321 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $6,545,427 | 238,536 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $9,706,421 | 381,242 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $14,322,899 | 565,452 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $23,023,032 | 744,600 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $39,029,594 | 966,797 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $33,676,705 | 1,277,084 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $12,734,725 | 740,391 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $12,924,773 | 779,540 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $4,962,227 | 651,211 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $8,659,797 | 871,207 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $1,373,468 | 151,263 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $5,171,912 | 509,548 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $10,111,232 | 606,189 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $2,189,860 | 46,722 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $955,791 | 15,679 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $29,803,804 | 483,828 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $11,703,923 | 164,589 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $4,959,206 | 132,175 | Shares | Sole | 2020-11-16 | |
| No filing history on record for this holder in this stock. | ||||||