Position in BBIO
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$231,738,058
+$82,808,433 QoQ
Shares Held
3,120,631
+60.3% QoQ
Ownership
1.59%
of shares outstanding
% of Portfolio
0.21%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Sep 2020
23 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in BBIO Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. BBIO ranks #5 (4.2% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
This page
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in BBIO
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23 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $231,738,058 | 3,120,631 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $148,929,625 | 1,947,047 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $120,965,195 | 2,328,941 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $101,000,913 | 2,339,067 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $29,153,606 | 843,321 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $6,545,427 | 238,536 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $9,706,421 | 381,242 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $14,322,899 | 565,452 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $23,023,032 | 744,600 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $39,029,594 | 966,797 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $33,676,705 | 1,277,084 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $12,734,725 | 740,391 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $12,924,773 | 779,540 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $4,962,227 | 651,211 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $8,659,797 | 871,207 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $1,373,468 | 151,263 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $5,171,912 | 509,548 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $10,111,232 | 606,189 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $2,189,860 | 46,722 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $955,791 | 15,679 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $29,803,804 | 483,828 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $11,703,923 | 164,589 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $4,959,206 | 132,175 | Shares | Sole | 2020-11-16 | |
| No filing history on record for this holder in this stock. | ||||||