Position in ALNY
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$659,283,951
+$414,283,833 QoQ
Shares Held
1,992,577
+223.4% QoQ
Ownership
1.50%
of shares outstanding
% of Portfolio
0.61%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2021
16 quarters on record
Voting authority
Sole 96.34242491005367.ToString("F0")%
Shared 0.ToString("F0")%
None 3.6575750899463353.ToString("F0")%
Common Shares in ALNY Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,502,861,072 across 315 Biotechnology names. ALNY ranks #1 (12.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
This page
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in ALNY
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16 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $659,283,951 | 1,992,577 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $245,000,118 | 616,120 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $271,742,256 | 595,926 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $111,948,327 | 343,305 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $53,305,998 | 197,415 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $25,205,701 | 107,117 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $5,266,274 | 19,148 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $25,009,074 | 102,918 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $15,320,418 | 102,512 | Shares | Sole | 2024-05-15 | |
| 2023-09-30 | $584,430 | 3,300 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $42,673,629 | 224,669 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $33,522,750 | 167,346 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $43,420,318 | 182,707 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $43,377,073 | 216,712 | Shares | Sole | 2022-11-14 | |
| 2022-03-31 | $12,075,132 | 73,949 | Shares | Sole | 2022-05-16 | |
| 2021-03-31 | $5,170,236 | 36,619 | Shares | Sole | 2021-05-17 | |
| No filing history on record for this holder in this stock. | ||||||