TWO SIGMA INVESTMENTS, LP

Position in INCY — Incyte Corp

CIK 1179392 NEW YORK, NY

Position in INCY

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$39,145,825

+$35,516,127 QoQ

Shares Held

415,914

+1031.8% QoQ

Ownership

0.208%

of shares outstanding

% of Portfolio

0.04%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

21 quarters on record

Voting authority Sole 99.5191313588867.ToString("F0")% Shared 0.ToString("F0")% None 0.48086864111330707.ToString("F0")%

Healthcare · as of Mar 31, 2026

TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. INCY ranks #27 (0.7% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ALNY	Alnylam Pharmaceuticals, Inc.	1,992,577	$659,283,951
2	REGN	Regeneron Pharmaceuticals, Inc.	812,236	$627,566,023
3	MRNA	Moderna, Inc.	9,086,404	$461,589,323
4	IONS	Ionis Pharmaceuticals Inc	5,857,629	$439,849,361
5	BBIO	BridgeBio Pharma, Inc.	3,120,631	$231,738,058
6	VRTX	Vertex Pharmaceuticals Inc / Ma	378,146	$168,857,314
7	RVMD	Revolution Medicines, Inc.	1,558,807	$151,593,980
8	VKTX	Viking Therapeutics, Inc.	4,432,142	$144,221,900

21 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$39,145,825	415,914	+1031.8%	Shares	Sole	2026-05-15
2025-12-31	$3,629,698	36,749	-23.7%	Shares	Sole	2026-02-17
2025-09-30	$4,083,516	48,149	-25.2%	Shares	Sole	2025-11-14
2025-06-30	$4,382,166	64,349	+12.9%	Shares	Sole	2025-08-14
2025-03-31	$3,450,441	56,985	+103.2%	Shares	Sole	2025-05-15
2024-12-31	$1,937,344	28,049	+36.3%	Shares	Sole	2025-02-14
2024-09-30	$1,360,602	20,584	-90.6%	Shares	Sole	2024-11-14
2024-06-30	$13,220,191	218,083	-79.3%	Shares	Sole	2024-08-14
2024-03-31	$60,074,181	1,054,488	-44.8%	Shares	Sole	2024-05-15
2023-12-31	$120,041,105	1,911,787	+16.3%	Shares	Sole	2024-02-14
2023-09-30	$94,955,913	1,643,689	-21.9%	Shares	Sole	2023-11-14
2023-06-30	$131,015,956	2,104,674	+255.9%	Shares	Sole	2023-08-14
2023-03-31	$42,735,780	591,335	+50.4%	Shares	Sole	2023-05-15
2022-12-31	$31,573,551	393,097	+549.8%	Shares	Sole	2023-02-14
2022-09-30	$4,031,586	60,498	-84.1%	Shares	Sole	2022-11-14
2022-06-30	$28,876,121	380,099	-31.9%	Shares	Sole	2022-08-15
2022-03-31	$44,338,994	558,285	+3354.1%	Shares	Sole	2022-05-16
2020-12-31	$1,405,857	16,163	-91.0%	Shares	Sole	2021-02-16
2020-09-30	$16,170,340	180,191	+229.2%	Shares	Sole	2020-11-16
2020-06-30	$5,690,693	54,734	-63.6%	Shares	Sole	2020-08-14
2020-03-31	$11,019,357	150,476	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.