Position in EXEL
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$229,058,537
+$134,434,105 QoQ
Shares Held
4,209,861
+90.8% QoQ
Ownership
1.70%
of shares outstanding
% of Portfolio
0.19%
of 13F equity value
Holder Rank
#16
of 739 holders
Holding Since
Mar 2020
22 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in EXEL Over Time
Shares Held
Position Value (USD)
Derivatives in EXEL
reported options exposure · as of Sep 30, 2021CallValue
$274,820
CallShares
13,000
PutValue
$0
PutShares
0
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,272,047,596 across 342 Biotechnology names. EXEL ranks #6 (3.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
This page
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in EXEL
Export CSV
24 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $229,058,537 | 4,209,861 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $94,624,432 | 2,206,212 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $12,000,259 | 273,791 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $1,623,461 | 39,309 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $28,268,459 | 641,299 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $59,045,528 | 1,599,283 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $44,240,814 | 1,328,553 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $22,048,780 | 849,664 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $12,238,442 | 544,657 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $17,586,848 | 741,123 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $13,797,632 | 575,141 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $39,433,896 | 1,804,755 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $33,032,686 | 1,728,555 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $17,957,607 | 925,173 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $2,210,183 | 137,792 | Shares | Sole | 2023-02-14 | |
| 2022-06-30 | $5,471,329 | 262,792 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $21,050,477 | 928,561 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $12,803,092 | 700,388 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $12,702,011 | 600,852 | Shares | Sole | 2021-11-15 | |
| 2021-09-30 | $274,820 | 13,000 | Call | Sole | 2021-11-15 | |
| 2020-09-30 | $293,400 | 12,000 | Put | Sole | 2020-11-16 | |
| 2020-09-30 | $236,235 | 9,662 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $25,300,715 | 1,065,742 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $308,238 | 17,900 | Call | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||