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ALNY · Alnylam Pharmaceuticals, Inc.

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$228.65 +1.53 (+0.67%) At close · Aug 14
Market Cap
$30.60B
Shares
133.81M

Price & Indicators

Indicators
Price
Panels
Event markers
20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$228.65 Open$223.52 Day$220.23–228.98 52W close$205.48–491.22 Avg vol 30d2.1M Short int4.8M · 3.6% float · 2.2d Short vol51% Last earningsJul 30, 2026 DataJan 2020–Aug 2026 Filing10-Q · Jul 30

Up next

Next earnings call
Oct 29, 2026 Est · unconfirmed · in 11 wks
FQ3-26 quarter ends
~Sep 30, 2026 Est
Latest filing: 10-Q
filed Jul 30, 2026

AI Brief

TL;DR.

Bullish
    Bearish

      AI-generated from the earnings call and 8-K · may contain errors · not investment advice

      Ask ALVIS about this →

      Equibles Rating

      blended score · not investment advice
      Overall
      Sell
      SellHoldBuy
      Technical Neutral Momentum Very Weak Sentiment Neutral Fundamentals Excellent Quant / Vol Very High
      Market backdrop VIX 14.3 · calm Equity put/call 0.52
      Technical
      price trend
      Neutral
      50 / 200-day cross No cross
      Price vs 200-day avg −32%
      below
      Price vs 50-day avg −16%
      below
      RSI (14) 40
      neutral
      MACD trend Positive
      52-week position 8%
      near low
      Volume (OBV) Bullish div.
      accumulating
      Momentum
      relative strength
      Very Weak
      1-month return −15%
      trailing
      6-month return −31%
      trailing
      YTD return −43%
      this year
      Relative strength −44%
      vs S&P · 6-mo
      Sentiment
      smart money
      Neutral
      Trend (MA cross) No cross
      50d $273 › 200d $337 — 200d above 50d
      Institutional flow Distributing
      -3% holders QoQ · +87 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Falling
      3.59% of float · ▼ -16.8% MoM · 2.2 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Steady
      770 holders — mid 3-yr range
      Squeeze score 35
      low risk · 0–100
      Fundamentals
      Excellent
      Revenue growth +23%
      Y/Y
      EPS growth +207%
      Y/Y
      Free cash flow $465.4M
      Balance sheet $981.6M
      net cash
      Quant / Vol
      risk profile
      Very High
      Volatility 46%
      annualized · 1-yr
      Max drawdown −58%
      past year
      ATR 5.7%
      of price · 14-day

      Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

      Guidance & track record

      Latest guidance · from the 8-K filed Jul 30, 2026
      TTR Net Product Revenue · Full-Year 2026 $4.2B – $4.5B
      Prior guidance period ended · from the Earnings Call filed Sep 30, 2025
      Total net product revenue · 2025 $2.95B – $3.05B

      Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

      Technicals

      trend & momentum for long-term holders Neutral
      3 · 2 · 2
      50 / 200-day cross
      No cross Neutral
      Price vs 200-day avg
      −32% Bearish
      Price vs 50-day avg
      −16% Bearish
      RSI (14)
      40 Neutral
      MACD trend
      Positive Bullish
      52-week position
      8% Bearish
      Volume (OBV)
      Bullish div. Bullish
      Market signals — smart money & positioning
      Mixed
      Trend (MA cross) No cross
      50d $273 › 200d $337 — 200d above 50d
      Institutional flow Distributing
      -3% holders QoQ · +87 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Falling
      3.59% of float · ▼ -16.8% MoM · 2.2 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Steady
      770 holders — mid 3-yr range
      Price context
      position in its 52-week range
      Range low $205 Now $229 · 8% Range high $491
      vs 200-day avg -32% vs 50-day avg -16%

      Illustrative technical + ownership context — a signal mix, not investment advice.

      Key metrics

      the company's own KPIs, from written earnings releases and filings
      Metric Latest Period YoY
      AMVUTTRA % Change 187% Q1 2026 —
      AMVUTTRA % Change At CER 183% Q1 2026 —
      Total Rare net product revenues % Change 15% Q1 2026 —
      Total TTR net product revenues % Change 153% Q1 2026 —
      Total TTR net product revenues % Change At CER 150% Q1 2026 —
      Non-GAAP Net income (loss) per common share — diluted non-GAAP $1.25 Q4 2025 —
      Non-GAAP Net income (loss) per share — diluted non-GAAP $5.08 Full Year 2025 —
      global net product revenues for AMVUTTRA and ONPATTRO 2.31B full year 2025 —
      global net product revenues for GIVLAARI and OXLUMO 308M full year 2025 —

      Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

      Versus peers

      Biotechnology — same industry group
      Open screener →
      Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
      ALNY
      Alnylam Pharmaceuticals, Inc.
      this stock
      		$30.60B -42.5% +22.9% — 3.6%
      ONC
      BeOne Medicines Ltd.
      		 $513.62B +14.4% +22179.2% 789.7 0.1%
      VRTX
      Vertex Pharmaceuticals Inc / Ma
      		 $128.19B +11.6% +46.2% 29.5 1.6%
      REGN
      Regeneron Pharmaceuticals, Inc.
      		 $82.72B +4.1% +20.8% 19.9 3.3%
      ARGX
      Argenx SE
      		 $52.94B +1.2% — — 2.1%

      Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

      At a glance

      key data from every section
      Ownership
      Institutional Holders Accumulating
      Holders
      770
      % held
      101.0%
      Net QoQ
      +4.6M sh
      Top holder
      FMR LLC
      Held Float
      View
      Held by Funds
      Fund positions
      759
      View
      Short & Settlement
      Short Interest Falling
      Shares short
      4.8M
      Days to cover
      2.2d
      Change
      -970.2K sh
      View
      Short Volume
      Short vol %
      51%
      As of
      Aug 14, 2026
      Short Total
      View
      Fails to Deliver
      FTD shares
      4
      Value
      $1.2K
      As of
      Jul 13, 2026
      View
      Off-Exchange
      Off-exchange %
      46.4%
      Week of
      Jul 6, 2026
      Off-exch Lit
      View
      Smart Money
      Congressional Trades Sell
      Member
      Jefferson Shreve
      Amount
      $15.0K–$50.0K
      Traded
      May 12, 2025
      View
      Financials
      Financials
      Revenue (FY)
      $3.7B
      Net income (FY)
      $313.7M
      EPS diluted
      $2.33
      View
      Filings
      SEC Filings
      Latest
      8-K
      Filed
      Jul 30, 2026
      This year
      11
      View
      Proposed Sales
      Value
      $1.1M
      Shares
      3.8K
      Filed
      Jun 1, 2026
      View
      Earnings & Events
      Earnings Calls
      Last call
      Jul 30, 2026
      View

      Performance

      5D 20D 120D MTD YTD
      ALNY +4.3% -14.5% -30.6% +11.3% -42.5%
      SPY +0.4% +4.5% +13.8% +3.9% +13.9%
      vs SPY +3.9% -19.0% -44.4% +7.3% -56.4%
      Key facts CIK 1178670 CUSIP 02043Q107 13F (30d) 739 filings 705 filers Visit website Investor relations

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