RTW INVESTMENTS, LP

CIK

1493215

City

NEW YORK

State / Country

NY

Stock

APGE — Apogee Therapeutics, Inc.

Top Portfolio Positions

87 positions · $10,097,544,596 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio	Open
MDGL	Madrigal Pharmaceuticals, Inc. Healthcare	1,993,687	$1,043,635,333	10.34%
INSM	INSMED Inc Healthcare	4,842,880	$791,907,737	7.84%
PTGX	Protagonist Therapeutics, Inc Healthcare	5,059,053	$533,224,186	5.28%
PTCT	Ptc Therapeutics, Inc. Healthcare	7,746,415	$527,763,253	5.23%
ARGX	Argenx SE Healthcare	709,446	$518,072,941	5.13%
CGON	CG Oncology, Inc. Healthcare	6,984,808	$472,731,805	4.68%
CELC	Celcuity Inc. Healthcare	3,039,621	$346,942,340	3.44%
TNGX	Tango Therapeutics, Inc. Healthcare	13,300,620	$278,248,970	2.76%
ERAS	Erasca, Inc. Healthcare	16,157,175	$261,423,091	2.59%
NTRA	Natera, Inc. Healthcare	1,250,000	$249,987,500	2.48%

Portfolio Trend

25 quarters · across all stocks

Holdings in APGE

Compact Export CSV

Shares Held

Position Value (USD)

11 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$234,169,104	2,782,097	+2.6%	Shares	Sole	2026-05-15
2025-12-31	$204,709,081	2,712,097	0.0%	Shares	Sole	2026-02-17
2025-09-30	$107,751,613	2,712,097	0.0%	Shares	Sole	2025-11-14
2025-06-30	$117,786,372	2,712,097	0.0%	Shares	Sole	2025-08-14
2025-03-31	$101,323,943	2,712,097	0.0%	Shares	Sole	2025-05-15
2024-12-31	$122,857,994	2,712,097	+0.0%	Shares	Sole	2025-02-14
2024-09-30	$159,308,519	2,712,096	0.0%	Shares	Sole	2024-11-14
2024-06-30	$106,720,977	2,712,096	+9.9%	Shares	Sole	2024-08-14
2024-03-31	$163,971,421	2,467,591	+15.2%	Shares	Sole	2024-05-15
2023-12-31	$59,863,992	2,142,591	0.0%	Shares	Sole	2024-02-14
2023-09-30	$45,637,188	2,142,591	—	Shares	Sole	2023-11-14
No 13F history on record for this holder in this stock.