MIST · Milestone Pharmaceuticals Inc.

$1.05 +0.02 (+1.94%)

Market Cap

$134.46M

124.50M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 78

Total Value: $66,809,000

Total Shares: 49,857,483

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 78 13F filers · Δ vs Mar 31, 2026

Top Holder

18.2%

−4.6 pts

Top 5

66.4%

+6.5 pts

Top 10

84.6%

+7.3 pts

HHI

1,054

Broadly held+26

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: -9

Institutional value: +41.0%

Shares held: +25.2%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large Point72 Asset Management, L.P.	+4,325,455	5,411,138
Small Propel Bio Management, LLC	+3,311,269	7,429,590
Small Simplify Asset Management Inc.	+1,842,974	3,349,379
Mega MILLENNIUM MANAGEMENT LLC	+1,597,894	3,142,219
Large RTW INVESTMENTS, LP	+1,502,335	7,833,336

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large Balyasny Asset Management L.P.	−630,827	220,498
Mega TWO SIGMA INVESTMENTS, LP	−277,161	2,040,015
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP	−234,351	394,795
Large MARSHALL WACE, LLP	−146,835	1,797,695
Mid GROUP ONE TRADING LLC	−129,540	224

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Small Kalehua Capital Management LLC	1,269,237	$1,700,777
Small Cascades Capital Asset Management, LLC	83,610	$112,037
Small TWO SIGMA SECURITIES, LLC	16,745	$22,438
Mid WINTON GROUP Ltd	14,300	$19,162
Mid Virtu Financial LLC	11,613	$15,561

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mega GOLDMAN SACHS GROUP INC	2,000,025	$2,380,029
Large RENAISSANCE TECHNOLOGIES LLC	129,705	$154,348
Large HRT FINANCIAL LP	62,256	$74,084
Mega Invesco Ltd.	41,356	$49,213
Mega NORTHERN TRUST CORP	38,779	$46,147

Filter: New 6 Increased 23 Reduced 23 Sold out 15 Unchanged 26

Showing 85 of 85

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Pavaki Capital Management LLC

$12,150,916

18.19%

9,067,848

RTW INVESTMENTS, LP

$10,496,670

15.71%

7,833,336

Propel Bio Management, LLC

$9,955,650

14.90%

7,429,590

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Simplify Asset Management Inc.	7,429,590	$9,955,650	100.0%	Defined

Point72 Asset Management, L.P.

$7,250,924

10.85%

5,411,138

Simplify Asset Management Inc.

$4,488,167

6.72%

3,349,379

MILLENNIUM MANAGEMENT LLC

$4,210,573

6.30%

3,142,219

TWO SIGMA INVESTMENTS, LP

$2,733,620

4.09%

2,040,015

MARSHALL WACE, LLP

$2,408,910

3.61%

1,797,695

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	1,797,695	$2,408,910	100.0%	Other

Kalehua Capital Management LLC

$1,700,777

2.55%

1,269,237

Lion Point Capital, LP

$1,098,800

1.64%

820,000

TORONTO DOMINION BANK

$1,005,000

1.50%

750,000

Boxer Capital Management, LLC

$893,332

1.34%

666,666

AMERIPRISE FINANCIAL INC

$893,332

1.34%

666,666

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	666,666	$893,332	100.0%	Defined

MORGAN STANLEY

$851,182

1.27%

635,211

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY CAPITAL SERVICES, LLC	603,686	$808,939	95.0%	Defined
MORGAN STANLEY SMITH BARNEY LLC	31,525	$42,243	5.0%	Defined

UBS Group AG

$623,638

0.93%

465,403

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	413,690	$554,344	88.9%	Defined
UBS AG	12,467	$16,705	2.7%	Defined
UBS Securities LLC	39,246	$52,589	8.4%	Defined

BOOTHBAY FUND MANAGEMENT, LLC

$619,976

0.93%

462,669

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$482,259

0.72%

359,895

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	359,895	$482,259	100.0%	Other

Aptus Capital Advisors, LLC

$454,863

0.68%

339,450

GUARDIAN WEALTH ADVISORS, LLC / NC

$454,863

0.68%

339,450

Seven Fleet Capital Management LP

$362,112

0.54%

270,233

Squarepoint Ops LLC

$310,644

0.46%

231,824

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	231,824	$310,644	100.0%	Defined

LPL Financial LLC

$295,969

0.44%

220,873

Balyasny Asset Management L.P.

$295,467

0.44%

220,498

BNP PARIBAS ARBITRAGE, SA

$232,763

0.35%

173,704

CITADEL ADVISORS LLC

$220,162

0.33%

164,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	164,300	$220,162	100.0%	Defined

TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC

$201,000

0.30%

150,000

Wealthspire Advisors, LLC

$188,442

0.28%

140,629

Valeo Financial Advisors, LLC

$175,136

0.26%

130,699

ADAR1 Capital Management, LLC

$134,000

0.20%

100,000

Cascades Capital Asset Management, LLC

$112,037

0.17%

83,610

Quadrature Capital Ltd

$86,645

0.13%

64,661

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	64,661	$86,645	100.0%	Other

JANE STREET GROUP, LLC

$77,434

0.12%

57,787

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	57,787	$77,434	100.0%	Defined

CITADEL ADVISORS LLC

$75,174

0.11%

56,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	56,100	$75,174	100.0%	Defined

SIMPLEX TRADING, LLC

$72,589

0.11%

54,171

Bay Rivers Group

$62,488

0.09%

46,633

SG Americas Securities, LLC

$61,069

0.09%

45,574

GEODE CAPITAL MANAGEMENT, LLC

$54,657

0.08%

40,789

October Effect Ltd

$53,600

0.08%

40,000

Focus Partners Wealth

$48,240

0.07%

36,000

CITADEL ADVISORS LLC

$44,067

0.07%

32,887

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	1,441	$1,930	4.4%	Defined
Held directly	31,446	$42,137	95.6%	Defined

JANE STREET GROUP, LLC

$41,808

0.06%

31,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	31,200	$41,808	100.0%	Defined

RAYMOND JAMES FINANCIAL INC

$40,293

0.06%

30,070

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	26,600	$35,644	88.5%	Defined
Raymond James Financial Services Advisors, Inc.	3,470	$4,649	11.5%	Defined

Federation des caisses Desjardins du Quebec

$39,906

0.06%

29,781

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Desjardins Global Asset Management Inc.	16,781	$22,486	56.3%	Defined
Desjardins Securities inc.	13,000	$17,420	43.7%	Defined

Mariner, LLC

$37,292

0.06%

27,830

XTX Topco Ltd

$35,264

0.05%

26,317

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	26,317	$35,264	100.0%	Defined

Welch & Forbes LLC

$33,500

0.05%

25,000

Tower Research Capital LLC (TRC)

$32,407

0.05%

24,185

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	24,185	$32,407	100.0%	Defined

NATIONAL BANK OF CANADA /FI/

$31,490

0.05%

23,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
National Bank Financial Inc.	23,500	$31,490	100.0%	Defined

Exit Wealth Advisors, LLC.

$30,407

0.05%

22,692

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$30,284

0.05%

22,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	22,600	$30,284	100.0%	Other

STATE STREET CORP

$30,235

0.05%

22,564

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SSGA FUNDS MANAGEMENT, INC.	22,564	$30,235	100.0%	Defined

Taylor Financial Group, Inc.

$26,800

0.04%

20,000

Stephenson & Company, Inc.

$26,800

0.04%

20,000

HighTower Advisors, LLC

$26,800

0.04%

20,000

TWO SIGMA SECURITIES, LLC

$22,438

0.03%

16,745

Cetera Investment Advisers

$21,933

0.03%

16,368

JONES FINANCIAL COMPANIES LLLP

$21,440

0.03%

16,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	16,000	$21,440	100.0%	Sole

JANE STREET GROUP, LLC

$21,440

0.03%

16,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	16,000	$21,440	100.0%	Defined

Pathstone Holdings, LLC

$20,770

0.03%

15,500

AE Wealth Management LLC

$20,100

0.03%

15,000

Vision Retirement, LLC

$20,100

0.03%

15,000

EARNED WEALTH ADVISORS, LLC

$19,773

0.03%

14,756

Bronte Capital Management Pty Ltd.

$19,282

0.03%

14,390

WINTON GROUP Ltd

$19,162

0.03%

14,300

Beta Wealth Group, Inc.

$18,930

0.03%

14,127

Strategic Family Wealth Counselors, L.L.C.

$18,592

0.03%

13,875

Cambridge Investment Research Advisors, Inc.

$18,063

0.03%

13,480

Creative Planning

$17,527

0.03%

13,080

Rockefeller Capital Management L.P.

$16,750

0.03%

12,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER FINANCIAL LLC	12,500	$16,750	100.0%	Defined

Safeguard Investment Advisory Group, LLC

$16,624

0.02%

12,406

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$16,482

0.02%

12,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	12,300	$16,482	100.0%	Other

Virtu Financial LLC

$15,561

0.02%

11,613

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Virtu Americas LLC	11,613	$15,561	100.0%	Defined

Eaton Financial Holdings Company, LLC

$13,735

0.02%

10,250

INTEGRAL INVESTMENT ADVISORS, INC.

$13,400

0.02%

10,000

Secure Asset Management, LLC

$13,400

0.02%

10,000

ROYAL BANK OF CANADA

$8,974

0.01%

6,698

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Dominion Securities Inc.	6,458	$8,653	96.4%	Defined
RBC Europe Ltd	240	$321	3.6%	Defined

US BANCORP \DE\

$4,288

0.01%

3,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	3,200	$4,288	100.0%	Defined

Arax Advisory Partners

$4,091

0.01%

3,053

PNC FINANCIAL SERVICES GROUP, INC.

$3,752

0.01%

2,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	2,800	$3,752	100.0%	Defined

Aptus Capital Advisors, LLC

$670

0.00%

500

Medallion Wealth Advisors, LLC

$455

0.00%

340

Rialto Wealth Management, LLC

$402

0.00%

300

GROUP ONE TRADING LLC

$300

0.00%

224

Caitong International Asset Management Co., Ltd

$125

0.00%

SBI Securities Co., Ltd.

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	2,000,025	$2,380,029	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Capital Management LLC	41,356	$49,213	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST GLOBAL INVESTMENTS LTD	38,779	$46,147	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	20,468	$24,356	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ANCORA PRIVATE WEALTH ADVISORS, LLC	10,000	$11,900	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	125	$148	100.0%	Defined

Key facts CIK 1408443 CUSIP 59935V107 13F (30d) 74 filings 71 filers Visit website Investor relations