OBIO · Orchestra BioMed Holdings, Inc. · Holdings
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 77 13F filersWho Holds OBIO
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 77 filers, like-for-like change +19.9%; actively managed books +4.7%; index-like books +91.9%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 81.2% | 33 | +9.3% |
| Exempt adviser | 0.2% | 1 | -87.0% |
| Adviser | 0.1% | 1 | new |
| Bank | 5.0% | 10 | +188.7% |
| Benefit plan | 0.0% | 1 | -96.6% |
| Non-US | 0.2% | 4 | +440.6% |
| Holding company | 9.8% | 4 | +221.9% |
| Insurer | 0.0% | 0 | — |
| Unknown | 3.5% | 23 | +16.0% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 28.0% | 16 | +91.9% |
| Systematic-like | 4.3% | 7 | -48.6% |
| Concentrated | 6.2% | 8 | +17.4% |
| Diversified active | 61.6% | 46 | +11.5% |
| Not measured | 0.0% | 0 | — |
| Unknown | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 26.0% | 43 | +167.2% |
| Medium turnover | 59.5% | 15 | +7.9% |
| High turnover | 4.6% | 12 | -50.7% |
| Unknown | 9.9% | 7 | +7.6% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 10.3% | 11 | +9.7% |
| Medium horizon | 15.6% | 17 | +71.4% |
| Long horizon | 52.1% | 45 | +29.1% |
| Unknown | 22.0% | 4 | -10.4% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 6.4% | 12 | +19.8% |
| $1B to $10B | 21.8% | 19 | -2.0% |
| $10B to $100B | 39.0% | 10 | +8.8% |
| $100B or more | 32.8% | 36 | +64.1% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Individuals and high net worth | 0.8% | 7 | +10.3% |
| Pooled investment vehicles | 61.8% | 12 | +0.1% |
| Registered funds and BDCs | 14.4% | 7 | +22.9% |
| Insurance companies | 0.1% | 2 | new |
| Governments and sovereign funds | 0.2% | 2 | +312.3% |
| Other investment advisers | 0.0% | 0 | — |
| Diversified | 3.9% | 3 | +5511.8% |
| Pension and profit sharing plans | 0.0% | 0 | — |
| Unknown | 18.8% | 44 | +106.5% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 58.6% | 10 | -1.8% |
| Private equity funds | 0.1% | 2 | new |
| Securitized asset funds | 2.3% | 1 | new |
| Other private funds | 0.8% | 5 | +102.0% |
| Mixed private funds | 0.0% | 0 | — |
| Private funds, type not stated | 0.9% | 2 | +11.6% |
| No private funds | 15.4% | 13 | +34.6% |
| Venture capital funds | 3.2% | 1 | 0.0% |
| Real estate funds | 0.0% | 0 | — |
| Unknown | 18.7% | 43 | +136.0% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 98.1% | 62 | +20.3% |
| Outside the US | 1.9% | 15 | +1.1% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Conviction and Crowding
77 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).
Estimated Holder Cost Basis
Quarter ended Jun 30, 2026, on that quarter's share basisEstimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.
Estimated cost covers 90.9% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.
Shared Holders
Companies OBIO's active holders also own, quarter ended Jun 30, 2026| # | Company | Shared holders |
|---|---|---|
| 1 | SABS SAB Biotherapeutics, Inc. | 4 |
| 2 | LONA LeonaBio, Inc. | 3 |
| 3 | AQST Aquestive Therapeutics, Inc. | 4 |
| 4 | CGEM Cullinan Therapeutics, Inc. | 4 |
| 5 | IMVT Immunovant, Inc. | 4 |
| 6 | QTTB Q32 Bio Inc. | 3 |
| 7 | ARTV Artiva Biotherapeutics, Inc. | 3 |
| 8 | IMTX Immatics N.V. | 3 |
| 9 | CMPS COMPASS Pathways plc | 5 |
| 10 | ANL Adlai Nortye Group Ltd. | 3 |
Shareholder Targets
13F filers that own its peers but not OBIO, quarter ended Jun 30, 2026Found through its holder-overlap peers: SABS, LONA, AQST, CGEM, IMVT, QTTB, ARTV, IMTX, CMPS, ANL, MIST, PHAT, ENGN, SLDB, PTGX, TVTX, CLDX, MAZE, PALI, IDYA. 792 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | Jupiter Topco LLC Unknown, Diversified active | $1,391,292,018 10 held | TVTX, IDYA, PTGX |
| 2 | FARALLON CAPITAL MANAGEMENT LLC Registered adviser, Diversified active | $1,034,972,716 3 held | PTGX, IMVT, MAZE |
| 3 | WELLINGTON MANAGEMENT GROUP LLP Holding company, Diversified active | $899,724,410 13 held | PTGX, CLDX, TVTX |
| 4 | Deep Track Capital, LP Adviser, Diversified active | $788,360,351 5 held | IMVT, CMPS, MAZE |
| 5 | BAKER BROS. ADVISORS LP Registered adviser, Concentrated | $536,469,562 4 held | IMVT, IDYA, IMTX |
| 6 | T. Rowe Price Investment Management, Inc. Adviser, Diversified active | $422,898,272 4 held | IMTX, IMVT, MAZE |
| 7 | Kynam Capital Management, LP Registered adviser, Concentrated | $369,185,838 4 held | CLDX, TVTX, CGEM |
| 8 | Woodline Partners LP Registered adviser, Systematic-like | $368,627,860 14 held | PTGX, IMVT, CLDX |
| 9 | RA CAPITAL MANAGEMENT, L.P. Registered adviser, Concentrated | $356,181,379 5 held | ARTV, SLDB, QTTB |
| 10 | ADAGE CAPITAL PARTNERS GP, L.L.C. Registered adviser, Diversified active | $321,532,987 10 held | TVTX, IDYA, SABS |
Fund Ownership of OBIO by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 7.05% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 1.17% | 703,523 |
| Index ETFs | 5.88% | 3,534,531 |
| Active ETFs | 0.37% | 219,387 |
| Active funds | 0.84% | 502,060 |
| Unclassified | 0.01% | 3,182 |
| All registered funds | 8.26% | 4,962,683 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Large RTW INVESTMENTS, LP Registered adviser | $41,234,411 | 34.35% | 9,556,063 | Shares | 2026-08-14 | |
| Mid PERCEPTIVE ADVISORS LLC Registered adviser | $21,738,564 | 18.11% | 5,037,906 | Shares | 2026-08-14 | |
| Mega BlackRock, Inc. Holding company | $10,832,316 | 9.02% | 2,510,387 | Shares | 2026-08-07 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $8,728,882 | 7.27% | 2,022,916 | Shares | 2026-08-13 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC Registered adviser | $4,349,122 | 3.62% | 1,007,908 | Shares | 2026-08-12 | |
| Large Alyeska Investment Group, L.P. Registered adviser | $4,315,000 | 3.59% | 1,000,000 | Shares | 2026-08-14 | |
| Small Propel Bio Management, LLC Registered adviser | $3,869,264 | 3.22% | 896,701 | Shares | 2026-08-13 | |
| Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Registered adviser | $2,770,894 | 2.31% | 642,154 | Shares | 2026-08-13 | |
| Mega STATE STREET CORP Bank | $2,226,755 | 1.86% | 516,050 | Shares | 2026-09-22 | |
| Mid RICE HALL JAMES & ASSOCIATES, LLC Registered adviser | $1,829,560 | 1.52% | 424,000 | Shares | 2026-08-07 | |
| Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC Registered adviser | $1,508,282 | 1.26% | 349,544 | Shares | 2026-08-14 | |
| Mega NORTHERN TRUST CORP Bank | $1,482,805 | 1.24% | 343,640 | Shares | 2026-08-13 | |
| Mega UBS Group AG Bank | $1,405,709 | 1.17% | 325,773 | Shares | 2026-08-13 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $1,261,071 | 1.05% | 292,253 | Shares | 2026-08-13 | |
| Mega VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser | $1,186,508 | 0.99% | 274,973 | Shares | 2026-08-13 | |
| Small Knott David M Jr | $1,094,504 | 0.91% | 253,651 | Shares | 2026-08-12 | |
| Mid Flat Footed LLC Registered adviser | $1,084,670 | 0.90% | 251,372 | Shares | 2026-08-14 | |
| Mid Simplify Asset Management Inc. Registered adviser | $946,654 | 0.79% | 219,387 | Shares | 2026-07-16 | |
| Mega GOLDMAN SACHS GROUP INC Holding company | $774,999 | 0.65% | 179,606 | Shares | 2026-08-14 | |
| Small Daytona Street Capital LLC | $765,980 | 0.64% | 123,148 | Shares | 2026-10-15 | |
| Mid IFP Advisors, Inc Registered adviser | $563,084 | 0.47% | 90,528 | Shares | 2026-10-16 | |
| Small DAFNA Capital Management LLC Registered adviser | $547,318 | 0.46% | 126,841 | Shares | 2026-08-14 | |
| Large RENAISSANCE TECHNOLOGIES LLC Registered adviser | $388,350 | 0.32% | 90,000 | Shares | 2026-08-13 | |
| Mega Bank of New York Mellon Corp Bank | $371,533 | 0.31% | 86,103 | Shares | 2026-08-06 | |
| Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC Registered adviser | $347,789 | 0.29% | 80,600 | Shares | 2026-08-14 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $283,944 | 0.24% | 65,804 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $242,464 | 0.20% | 56,191 | Shares | 2026-09-02 | |
| Mega Nuveen, LLC | $224,889 | 0.19% | 52,118 | Shares | 2026-08-11 | |
| Small Holos Integrated Wealth LLC | $222,632 | 0.19% | 51,595 | Shares | 2026-07-15 | |
| Large NewEdge Advisors, LLC Registered adviser | $190,218 | 0.16% | 44,083 | Shares | 2026-08-12 | |
| Mega DEUTSCHE BANK AG\ Non-US | $171,183 | 0.14% | 39,672 | Shares | 2026-08-07 | |
| Mid XTX Topco Ltd | $167,482 | 0.14% | 38,814 | Shares | 2026-08-14 | |
| Mega WELLS FARGO & COMPANY/MN Bank | $156,876 | 0.13% | 36,356 | Shares | 2026-08-14 | |
| Large HighTower Advisors, LLC Registered adviser | $152,643 | 0.13% | 35,375 | Shares | 2026-08-05 | |
| Mid Affinity Asset Advisors, LLC Registered adviser | $144,121 | 0.12% | 33,400 | Shares | 2026-08-13 | |
| Mega PRICE T ROWE ASSOCIATES INC /MD/ Registered adviser | $141,053 | 0.12% | 32,689 | Shares | 2026-08-14 | |
| Mega RHUMBLINE ADVISERS Registered adviser | $137,821 | 0.11% | 31,940 | Shares | 2026-08-12 | |
| Small Meramec Financial Planners, LLC Registered adviser | $129,450 | 0.11% | 30,000 | Shares | 2026-07-29 | |
| Mega MORGAN STANLEY Holding company | $125,824 | 0.10% | 29,160 | Shares | 2026-08-13 | |
| Mid ALGERT GLOBAL LLC Registered adviser | $122,917 | 0.10% | 28,486 | Shares | 2026-08-13 | |
| Small AXQ CAPITAL, LP Registered adviser | $109,808 | 0.09% | 25,448 | Shares | 2026-08-06 | |
| Mega Invesco Ltd. Adviser | $106,532 | 0.09% | 24,689 | Shares | 2026-08-14 | |
| Large MetLife Investment Management, LLC Registered adviser | $103,534 | 0.09% | 23,994 | Shares | 2026-08-14 | |
| Mega BANK OF AMERICA CORP /DE/ Bank | $102,791 | 0.09% | 23,822 | Shares | 2026-08-14 | |
| Mega TWO SIGMA INVESTMENTS, LP Registered adviser | $97,359 | 0.08% | 22,563 | Shares | 2026-08-14 | |
| Mega CANADA PENSION PLAN INVESTMENT BOARD Non-US | $91,046 | 0.08% | 21,100 | Shares | 2026-08-14 | |
| Mega JPMORGAN CHASE & CO Bank | $90,096 | 0.08% | 20,880 | Shares | 2026-08-12 | |
| Large NEW YORK STATE COMMON RETIREMENT FUND | $88,026 | 0.07% | 20,400 | Shares | 2026-07-29 | |
| Mega CITIGROUP INC Bank | $87,011 | 0.07% | 20,165 | Shares | 2026-08-03 | |
| Small ABLE Financial Group, LLC | $83,360 | 0.07% | 13,402 | Shares | 2026-10-14 | |
| Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $79,188 | 0.07% | 18,352 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $75,944 | 0.06% | 17,600 | Put | 2026-09-02 | |
| Mega JANE STREET GROUP, LLC | $66,278 | 0.06% | 15,360 | Shares | 2026-08-14 | |
| Mega Vanguard Global Advisers, LLC Registered adviser | $60,185 | 0.05% | 13,948 | Shares | 2026-08-13 | |
| Mega BARCLAYS PLC Bank | $58,329 | 0.05% | 13,518 | Shares | 2026-08-14 | |
| Small Sargent Investment Group, LLC Registered adviser | $56,612 | 0.05% | 13,120 | Shares | 2026-08-11 | |
| Mid Frec Markets, Inc. | $56,302 | 0.05% | 13,048 | Shares | 2026-08-13 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $52,211 | 0.04% | 12,100 | Call | 2026-09-02 | |
| Large Police & Firemen's Retirement System of New Jersey | $50,722 | 0.04% | 11,755 | Shares | 2026-07-23 | |
| Mega JANE STREET GROUP, LLC | $49,191 | 0.04% | 11,400 | Put | 2026-08-14 | |
| Small Garden State Investment Advisory Services LLC Registered adviser | $45,575 | 0.04% | 10,562 | Shares | 2026-08-11 | |
| Mid China Universal Asset Management Co., Ltd. | $41,121 | 0.03% | 9,530 | Shares | 2026-07-24 | |
| Mega BNP PARIBAS ARBITRAGE, SA Non-US | $35,443 | 0.03% | 8,214 | Shares | 2026-08-13 | |
| Mega Legal & General Group Plc | $16,932 | 0.01% | 3,924 | Shares | 2026-08-14 | |
| Mid Ameritas Investment Partners, Inc. Registered adviser | $15,607 | 0.01% | 3,617 | Shares | 2026-08-13 | |
| Mid Tower Research Capital LLC (TRC) | $15,538 | 0.01% | 3,601 | Shares | 2026-08-11 | |
| Mega Russell Investments Group, Ltd. | $13,751 | 0.01% | 3,187 | Shares | 2026-08-06 | |
| Large Mirae Asset Global Investments Co., Ltd. | $11,555 | 0.01% | 2,678 | Shares | 2026-07-22 | |
| Mid SIMPLEX TRADING, LLC | $11,063 | 0.01% | 2,564 | Shares | 2026-08-12 | |
| Mega ROYAL BANK OF CANADA Bank | $8,042 | 0.01% | 1,864 | Shares | 2026-08-14 | |
| Mid GF FUND MANAGEMENT CO. LTD. | $5,061 | 0.00% | 1,173 | Shares | 2026-08-07 | |
| Mega JONES FINANCIAL COMPANIES LLLP | $3,831 | 0.00% | 888 | Shares | 2026-08-14 | |
| Mega CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Benefit plan | $2,368 | 0.00% | 549 | Shares | 2026-08-24 | |
| Mid GAMMA Investing LLC Registered adviser | $1,841 | 0.00% | 296 | Shares | 2026-10-08 | |
| Mega FMR LLC Holding company | $1,142 | 0.00% | 265 | Shares | 2026-08-13 | |
| Large Farther Finance Advisors, LLC Registered adviser | $883 | 0.00% | 142 | Shares | 2026-10-08 | |
| Mid Sterling Capital Management LLC Registered adviser | $604 | 0.00% | 140 | Shares | 2026-07-28 | |
| Mid Optiver Holding B.V. | $172 | 0.00% | 40 | Shares | 2026-08-12 | |
| Small Caitong International Asset Management Co., Ltd | $64 | 0.00% | 15 | Shares | 2026-08-05 | |
| Mid SBI Securities Co., Ltd. Non-US | $25 | 0.00% | 6 | Shares | 2026-07-23 |