ROYAL BANK OF CANADA

Bank

Position in OBIO — Orchestra BioMed Holdings, Inc.

CIK 1000275 TORONTO, A6

Position in OBIO

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$3,977

+$2,438 QoQ

Shares Held

936

+152.3% QoQ

Ownership

0.002%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Jun 2023

12 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

ROYAL BANK OF CANADA holds $1,974,352,961 across 412 Biotechnology names. OBIO ranks #241 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	1,111,871	$496,494,870
2	IONS	Ionis Pharmaceuticals Inc	3,801,815	$285,478,282
3	REGN	Regeneron Pharmaceuticals, Inc.	351,171	$271,328,756
4	ALNY	Alnylam Pharmaceuticals, Inc.	791,515	$261,888,563
5	INCY	Incyte Corp	1,054,123	$99,214,053
6	INSM	INSMED Inc	523,101	$85,537,473
7	MRNA	Moderna, Inc.	999,340	$50,766,470
8	HALO	Halozyme Therapeutics, Inc.	658,290	$42,545,279

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$3,977	936	+152.3%	Shares	Defined	2026-05-15
2025-12-31	$1,539	371	-94.2%	Shares	Sole	2026-02-17
2025-09-30	$15,779	6,363	-18.7%	Shares	Defined	2025-11-14
2025-06-30	$20,981	7,829	+1175.1%	Shares	Defined	2025-11-21
2025-03-31	$2,627	614	-84.9%	Shares	Defined	2025-11-21
2024-12-31	$16,256	4,064	+44.5%	Shares	Defined	2025-02-14
2024-09-30	$14,458	2,813	+23.1%	Shares	Defined	2024-11-14
2024-06-30	$18,622	2,285	+244.1%	Shares	Defined	2024-11-06
2024-03-31	$3,498	664	-87.4%	Shares	Defined	2024-11-05
2023-12-31	$48,013	5,259	+163.9%	Shares	Defined	2024-02-14
2023-09-30	$17,378	1,993	+286.2%	Shares	Defined	2023-11-14
2023-06-30	$3,612	516	—	Shares	Defined	2023-08-14
No filing history on record for this holder in this stock.