Position in IONS
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$285,478,282
+$196,970,255 QoQ
Shares Held
3,801,815
+239.8% QoQ
Ownership
2.30%
of shares outstanding
% of Portfolio
0.07%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority
Sole 96.9785747070807.ToString("F0")%
Shared 2.8205212510340454.ToString("F0")%
None 0.20090404188525743.ToString("F0")%
Common Shares in IONS Over Time
Shares Held
Position Value (USD)
Derivatives in IONS
reported options exposure · as of Dec 31, 2025CallValue
$1,938,195
CallShares
24,500
PutValue
$3,773,547
PutShares
47,700
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026ROYAL BANK OF CANADA holds $1,974,323,419 across 406 Biotechnology names. IONS ranks #2 (14.5% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
1,111,871 | $496,494,870 | |
| 2 | IONS |
Ionis Pharmaceuticals Inc
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|
3,801,815 | $285,478,282 | |
| 3 | REGN |
Regeneron Pharmaceuticals, Inc.
|
351,171 | $271,328,756 | |
| 4 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
791,515 | $261,888,563 | |
| 5 | INCY |
Incyte Corp
|
1,054,123 | $99,214,053 | |
| 6 | INSM |
INSMED Inc
|
523,101 | $85,537,473 | |
| 7 | MRNA |
Moderna, Inc.
|
999,340 | $50,766,470 | |
| 8 | HALO |
Halozyme Therapeutics, Inc.
|
658,290 | $42,545,279 |
All Filings in IONS
Export CSV
39 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $285,478,282 | 3,801,815 | Shares | Defined | 2026-05-15 | |
| 2025-12-31 | $88,508,027 | 1,118,797 | Shares | Defined | 2026-02-17 | |
| 2025-12-31 | $3,773,547 | 47,700 | Put | Sole | 2026-02-17 | |
| 2025-12-31 | $1,938,195 | 24,500 | Call | Sole | 2026-02-17 | |
| 2025-09-30 | $9,054,128 | 138,400 | Put | Sole | 2025-11-14 | |
| 2025-09-30 | $80,245,739 | 1,226,624 | Shares | Defined | 2025-11-14 | |
| 2025-09-30 | $5,966,304 | 91,200 | Call | Sole | 2025-11-14 | |
| 2025-06-30 | $4,938,750 | 125,000 | Put | Sole | 2025-11-21 | |
| 2025-06-30 | $31,604,520 | 799,912 | Shares | Defined | 2025-11-21 | |
| 2025-03-31 | $18,587,161 | 616,081 | Shares | Defined | 2025-11-21 | |
| 2025-03-31 | $3,771,250 | 125,000 | Put | Sole | 2025-11-21 | |
| 2024-12-31 | $22,485,989 | 643,192 | Shares | Defined | 2025-02-14 | |
| 2024-12-31 | $4,370,000 | 125,000 | Put | Sole | 2025-02-14 | |
| 2024-12-31 | $1,398,400 | 40,000 | Call | Sole | 2025-02-14 | |
| 2024-09-30 | $26,846,166 | 670,149 | Shares | Defined | 2024-11-14 | |
| 2024-09-30 | $2,511,762 | 62,700 | Call | Sole | 2024-11-14 | |
| 2024-06-30 | $32,330,635 | 678,360 | Shares | Defined | 2024-11-06 | |
| 2024-06-30 | $8,307,138 | 174,300 | Call | Sole | 2024-11-06 | |
| 2024-03-31 | $1,083,750 | 25,000 | Call | Sole | 2024-11-05 | |
| 2024-03-31 | $31,742,471 | 732,237 | Shares | Defined | 2024-11-05 | |
| 2024-03-31 | $3,251,250 | 75,000 | Put | Sole | 2024-11-05 | |
| 2023-12-31 | $39,169,102 | 774,246 | Shares | Defined | 2024-02-14 | |
| 2023-12-31 | $25,295 | 500 | Call | Sole | 2024-02-14 | |
| 2023-09-30 | $22,680 | 500 | Call | Sole | 2023-11-14 | |
| 2023-09-30 | $30,093,817 | 663,444 | Shares | Defined | 2023-11-14 | |
| 2023-06-30 | $23,679,968 | 577,138 | Shares | Defined | 2023-08-14 | |
| 2023-03-31 | $17,725,501 | 495,957 | Shares | Defined | 2023-05-15 | |
| 2022-12-31 | $19,143,531 | 506,845 | Shares | Defined | 2023-02-14 | |
| 2022-09-30 | $19,320,723 | 436,824 | Shares | Defined | 2022-11-14 | |
| 2022-06-30 | $15,860,215 | 428,423 | Shares | Defined | 2022-08-15 | |
| 2022-03-31 | $16,464,350 | 444,502 | Shares | Defined | 2022-05-16 | |
| 2021-12-31 | $14,626,116 | 480,648 | Shares | Defined | 2022-02-14 | |
| 2021-09-30 | $16,419,873 | 489,561 | Shares | Defined | 2021-11-15 | |
| 2021-06-30 | $19,345,290 | 484,966 | Shares | Defined | 2021-08-16 | |
| 2021-03-31 | $7,176,243 | 159,614 | Shares | Defined | 2021-07-20 | |
| 2020-12-31 | $8,519,841 | 150,687 | Shares | Defined | 2021-02-16 | |
| 2020-09-30 | $7,331,117 | 154,502 | Shares | Defined | 2020-11-16 | |
| 2020-06-30 | $9,246,693 | 156,830 | Shares | Defined | 2020-08-14 | |
| 2020-03-31 | $7,595,624 | 160,652 | Shares | Defined | 2020-06-16 | |
| No filing history on record for this holder in this stock. | ||||||