Simplify Asset Management Inc.
Filing Date
Global Rank
#2,999
/ 8,603
▼ 396
· as of Mar 2026
Top Industry
Biotechnology
24.0%
3Y Alpha vs SPY
-5.4%
Period ended 3 months ago
Filed Apr 27, 2026 · 2mo
22 quarters · since Dec 2020
Clone Performance
Jul 2023–Jul 2026 · vs SPYHypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.
Cloned portfolio
+53.4%
SPY
+76.0%
Annualised alpha
-5.4%
Max drawdown
−18.9%
Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.
Portfolio Concentration
126 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
14.7%
−0.5 pts
Top 5
36.8%
+0.1 pts
Top 10
49.8%
−1.5 pts
HHI
436
Diversified−4
Portfolio Trend
22 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 63.0% | $242,657,558 |
| Unclassified | 15.8% | $60,676,833 |
| Energy | 8.0% | $30,892,900 |
| Industrials | 4.5% | $17,510,113 |
| Technology | 3.0% | $11,657,588 |
| Real Estate | 2.6% | $9,856,311 |
| Consumer Cyclical | 1.2% | $4,471,058 |
| Financial Services | 0.9% | $3,506,161 |
| Consumer Defensive | 0.7% | $2,512,266 |
| Communication Services | 0.3% | $1,311,840 |
| Utilities | 0.0% | $69,121 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
18 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| BNTC | Benitec Biopharma Inc. | +411,079 | 562,242 | $5,987,877 | |
| RITM | Rithm Capital Corp. | +220,000 | 336,593 | $3,190,901 | |
| KLRS | Kalaris Therapeutics, Inc. | +67,352 | 87,426 | $504,448 | |
| ZVRA | Zevra Therapeutics, Inc. | +58,265 | 100,630 | $937,871 | |
| MMM | 3M Co | +39,756 | 44,241 | $6,425,120 | |
| ABBV | AbbVie Inc. | +24,844 | 48,621 | $10,574,581 | |
| GILD | Gilead Sciences, Inc. | +23,866 | 61,345 | $8,549,652 | |
| HODL | VanEck Bitcoin ETF | +16,221 | 209,151 | $4,007,333 | |
| TMO | Thermo Fisher Scientific Inc. | +12,790 | 17,409 | $8,557,045 | |
| JNJ | Johnson & Johnson | +11,161 | 33,121 | $8,096,097 | |
| UTHR | UNITED THERAPEUTICS Corp | +10,412 | 34,251 | $20,310,157 | |
| ABEO | Abeona Therapeutics Inc. | +7,646 | 507,988 | $2,275,786 | |
| MFA | Mfa Financial, Inc. | +6,500 | 209,000 | $2,002,220 | |
| PLTR | Palantir Technologies Inc. | +1,963 | 11,704 | $1,712,061 | |
| IRWD | Ironwood Pharmaceuticals Inc | +501 | 11,447 | $40,178 | |
| QCOM | Qualcomm Inc/De | +171 | 5,574 | $717,819 | |
| LRCX | Lam Research Corp | +48 | 1,526 | $326,045 | |
| SPOT | Spotify Technology S.A. | +32 | 1,074 | $520,793 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
25 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CYPH | Cypherpunk Technologies Inc. | −1,851,183 | 21,139 | $16,805 | |
| PCT | PureCycle Technologies, Inc. | −162,786 | 1,770,778 | $9,190,337 | |
| TXG | 10x Genomics, Inc. | −131,274 | 354,703 | $7,530,344 | |
| CMPS | COMPASS Pathways plc | −130,948 | 159,052 | $879,557 | |
| IBIT | iShares Bitcoin Trust ETF | −120,000 | 1,475,000 | $56,669,500 | |
| IVA | Inventiva S.A. | −109,739 | 227,923 | $1,264,972 | |
| WRBY | Warby Parker Inc. | −109,512 | 290,831 | $6,127,809 | |
| UNH | Unitedhealth Group Inc | −96,906 | 2,901 | $784,981 | |
| ALHC | Alignment Healthcare, Inc. | −69,848 | 193,032 | $3,401,223 | |
| BHVN | Biohaven Ltd. | −59,802 | 898,400 | $7,600,464 | |
| PHAT | Phathom Pharmaceuticals, Inc. | −59,549 | 262,386 | $2,915,108 | |
| EYPT | EyePoint, Inc. | −49,122 | 326,142 | $4,203,970 | |
| VRDN | Viridian Therapeutics, Inc.\DE | −47,300 | 56,231 | $1,099,878 | |
| FULC | Fulcrum Therapeutics, Inc. | −43,680 | 115,994 | $889,673 | |
| AMGN | Amgen Inc | −36,506 | 15,844 | $5,574,711 | |
| OCS | Oculis Holding AG | −32,098 | 66,667 | $1,772,675 | |
| NLY | Annaly Capital Management Inc | −30,252 | 49,403 | $1,044,873 | |
| INSM | INSMED Inc | −26,107 | 10,783 | $1,763,236 | |
| DX | Dynex Capital Inc | −25,421 | 81,579 | $1,040,948 | |
| ARR | Armour Residential REIT, Inc. | −24,100 | 53,900 | $899,052 | |
| PCRX | Pacira BioSciences, Inc. | −23,608 | 62,653 | $1,415,957 | |
| AGNC | AGNC Investment Corp. | −23,552 | 103,485 | $1,037,954 | |
| SABS | SAB Biotherapeutics, Inc. | −20,997 | 187,230 | $717,090 | |
| REGN | Regeneron Pharmaceuticals, Inc. | −20,253 | 10,900 | $8,421,776 | |
| CVS | CVS HEALTH Corp | −20,111 | 54,013 | $3,879,213 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
25 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| NVO | Novo Nordisk A S | 327,357 | $12,030,369 | |
| AZN | Astrazeneca PLC | 25,818 | $5,091,825 | |
| IMUX | Immunic, Inc. | 438,932 | $4,872,145 | |
| CORT | Corcept Therapeutics Inc | 37,763 | $1,522,226 | |
| BRK-B | Berkshire Hathaway Inc | 2,622 | $1,256,462 | |
| OXLC | Oxford Lane Capital Corp. | 100,000 | $978,000 | |
| AQST | Aquestive Therapeutics, Inc. | 234,279 | $972,257 | |
| VOR | Vor Biopharma Inc. | 53,510 | $954,618 | |
| OBIO | Orchestra BioMed Holdings, Inc. | 219,387 | $932,394 | |
| MRK | Merck & Co., Inc. | 6,544 | $787,177 | |
| TRVI | Trevi Therapeutics, Inc. | 65,412 | $780,365 | |
| OCUL | Ocular Therapeutix, Inc | 90,000 | $762,300 | |
| UPB | Upstream Bio, Inc. | 77,793 | $700,137 | |
| FDMT | 4D Molecular Therapeutics, Inc. | 70,430 | $655,703 | |
| PANW | Palo Alto Networks Inc | 3,967 | $635,989 | |
| PALI | Palisade Bio, Inc. | 350,000 | $612,500 | |
| ADBE | Adobe Inc. | 2,266 | $550,819 | |
| CMCSA | Comcast Corp | 18,691 | $536,618 | |
| CHRS | Coherus Oncology, Inc. | 253,140 | $427,806 | |
| CAT | Caterpillar Inc | 574 | $406,656 | |
| CRVS | Corvus Pharmaceuticals, Inc. | 20,242 | $296,140 | |
| OVID | Ovid Therapeutics Inc. | 130,813 | $290,404 | |
| SNOW | Snowflake Inc. | 1,728 | $260,616 | |
| HON | Honeywell International Inc | 1,027 | $243,453 | |
| CIEN | Ciena Corp | 581 | $225,561 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
25 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| APLS | Apellis Pharmaceuticals, Inc. | 538,008 | $13,514,760 | |
| PEN | Penumbra Inc | 15,827 | $4,920,772 | |
| QQQ | Invesco Qqq Trust, Series 1 | 8,000 | $4,914,480 | |
| MLYS | Mineralys Therapeutics, Inc. | 114,182 | $4,143,664 | |
| IQV | Iqvia Holdings Inc. | 17,418 | $3,926,191 | |
| AGL | agilon health, inc. | 218,810 | $3,769,002 | |
| OSCR | Oscar Health, Inc. | 205,131 | $2,947,732 | |
| ARGX | Argenx SE | 3,115 | $2,619,559 | |
| HQY | Healthequity, Inc. | 27,329 | $2,503,609 | |
| ABVX | Abivax S.A. | 16,953 | $2,286,196 | |
| NKTR | Nektar Therapeutics | 28,000 | $1,183,840 | |
| APP | AppLovin Corp | 1,753 | $1,181,206 | |
| SNDX | Syndax Pharmaceuticals Inc | 54,715 | $1,149,562 | |
| CI | Cigna Group | 3,798 | $1,045,323 | |
| RGNX | REGENXBIO Inc. | 38,000 | $547,200 | |
| CHWY | Chewy, Inc. | 15,120 | $499,716 | |
| ALNY | Alnylam Pharmaceuticals, Inc. | 1,109 | $440,993 | |
| FLL | Full House Resorts Inc | 165,355 | $431,576 | |
| IDXX | Idexx Laboratories Inc /De | 584 | $395,093 | |
| FUBO | FuboTV Inc. | 12,602 | $381,084 | |
| MSI | Motorola Solutions, Inc. | 884 | $338,854 | |
| BX | Blackstone Inc. | 1,938 | $298,723 | |
| WDAY | Workday, Inc. | 1,375 | $295,322 | |
| ICLR | Icon PLC | 1,555 | $283,352 | |
| LENZ | LENZ Therapeutics, Inc. | 17,481 | $279,696 | |
| No positions match the current search. | ||||
126 positions ·
$385,121,749 total
· as of Mar 31, 2026
All sectors
Communication Services
Consumer Cyclical
Consumer Defensive
Energy
Financial Services
Healthcare
Industrials
Real Estate
Technology
Utilities
Showing 1–50
of 126 positions by value
· page 1 of 3
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| IBIT |
iShares Bitcoin Trust ETF
|
Reduced | 1,475,000 | $56,669,500 | 14.71% | |
| PAGP |
Plains Gp Holdings LP
Energy
|
Held | 1,272,360 | $30,892,900 | 8.02% | |
| UTHR |
UNITED THERAPEUTICS Corp
Healthcare
|
Added | 34,251 | $20,310,157 | 5.27% | |
| ALGN |
Align Technology Inc
Healthcare
|
Reduced | 106,897 | $18,325,352 | 4.76% | |
| LLY |
ELI LILLY & Co
Healthcare
|
Reduced | 16,703 | $15,362,918 | 3.99% | |
| NVO |
Novo Nordisk A S
Healthcare
|
NEW | 327,357 | $12,030,369 | 3.12% | |
| ABBV |
AbbVie Inc.
Healthcare
|
Added | 48,621 | $10,574,581 | 2.75% | |
| JAZZ |
Jazz Pharmaceuticals plc
Healthcare
|
Reduced | 51,730 | $9,779,556 | 2.54% | |
| PCT |
PureCycle Technologies, Inc.
Industrials
|
Reduced | 1,770,778 | $9,190,337 | 2.39% | |
| TMO |
Thermo Fisher Scientific Inc.
Healthcare
|
Added | 17,409 | $8,557,045 | 2.22% | |
| GILD |
Gilead Sciences, Inc.
Healthcare
|
Added | 61,345 | $8,549,652 | 2.22% | |
| REGN |
Regeneron Pharmaceuticals, Inc.
Healthcare
|
Reduced | 10,900 | $8,421,776 | 2.19% | |
| JNJ |
Johnson & Johnson
Healthcare
|
Added | 33,121 | $8,096,097 | 2.10% | |
| BHVN |
Biohaven Ltd.
Healthcare
|
Reduced | 898,400 | $7,600,464 | 1.97% | |
| TXG |
10x Genomics, Inc.
Healthcare
|
Reduced | 354,703 | $7,530,344 | 1.96% | |
| MMM |
3M Co
Industrials
|
Added | 44,241 | $6,425,120 | 1.67% | |
| WRBY |
Warby Parker Inc.
Healthcare
|
Reduced | 290,831 | $6,127,809 | 1.59% | |
| DHR |
Danaher Corp /De/
Healthcare
|
Reduced | 32,304 | $6,124,838 | 1.59% | |
| BNTC |
Benitec Biopharma Inc.
Healthcare
|
Added | 562,242 | $5,987,877 | 1.55% | |
| AMGN |
Amgen Inc
Healthcare
|
Reduced | 15,844 | $5,574,711 | 1.45% | |
| AZN |
Astrazeneca PLC
Healthcare
|
NEW | 25,818 | $5,091,825 | 1.32% | |
| ISRG |
Intuitive Surgical Inc
Healthcare
|
Reduced | 10,767 | $4,963,479 | 1.29% | |
| IMUX |
Immunic, Inc.
Healthcare
|
NEW | 438,932 | $4,872,145 | 1.27% | |
| EYPT |
EyePoint, Inc.
Healthcare
|
Reduced | 326,142 | $4,203,970 | 1.09% | |
| TSLA |
Tesla, Inc.
Consumer Cyclical
|
Reduced | 11,094 | $4,124,194 | 1.07% | |
| HODL |
VanEck Bitcoin ETF
|
Added | 209,151 | $4,007,333 | 1.04% | |
| CVS |
CVS HEALTH Corp
Healthcare
|
Reduced | 54,013 | $3,879,213 | 1.01% | |
| VRTX |
Vertex Pharmaceuticals Inc / Ma
Healthcare
|
Reduced | 7,936 | $3,543,741 | 0.92% | |
| ACHV |
Achieve Life Sciences, Inc.
Healthcare
|
Held | 1,184,512 | $3,482,465 | 0.90% | |
| ALHC |
Alignment Healthcare, Inc.
Healthcare
|
Reduced | 193,032 | $3,401,223 | 0.88% | |
| RITM |
Rithm Capital Corp.
Real Estate
|
Added | 336,593 | $3,190,901 | 0.83% | |
| ESTA |
Establishment Labs Holdings Inc.
Healthcare
|
Reduced | 53,009 | $3,009,851 | 0.78% | |
| PHAT |
Phathom Pharmaceuticals, Inc.
Healthcare
|
Reduced | 262,386 | $2,915,108 | 0.76% | |
| GEHC |
GE HealthCare Technologies Inc.
Healthcare
|
Reduced | 39,260 | $2,794,526 | 0.73% | |
| DCTH |
Delcath Systems, Inc.
Healthcare
|
Held | 261,126 | $2,423,249 | 0.63% | |
| ABEO |
Abeona Therapeutics Inc.
Healthcare
|
Added | 507,988 | $2,275,786 | 0.59% | |
| CLDX |
Celldex Therapeutics, Inc.
Healthcare
|
Reduced | 68,994 | $2,188,489 | 0.57% | |
| MFA |
Mfa Financial, Inc.
Real Estate
|
Added | 209,000 | $2,002,220 | 0.52% | |
| GH |
Guardant Health, Inc.
Healthcare
|
Reduced | 20,821 | $1,923,235 | 0.50% | |
| MIST |
Milestone Pharmaceuticals Inc.
Healthcare
|
Held | 1,506,405 | $1,792,621 | 0.47% | |
| OCS |
Oculis Holding AG
Healthcare
|
Reduced | 66,667 | $1,772,675 | 0.46% | |
| WMT |
Walmart Inc.
Consumer Defensive
|
Reduced | 14,217 | $1,766,888 | 0.46% | |
| INSM |
INSMED Inc
Healthcare
|
Reduced | 10,783 | $1,763,236 | 0.46% | |
| PLTR |
Palantir Technologies Inc.
Technology
|
Added | 11,704 | $1,712,061 | 0.44% | |
| ABT |
Abbott Laboratories
Healthcare
|
Reduced | 15,506 | $1,592,001 | 0.41% | |
| CSCO |
Cisco Systems, Inc.
Technology
|
Reduced | 19,859 | $1,540,859 | 0.40% | |
| LONA |
LeonaBio, Inc.
Healthcare
|
Held | 149,279 | $1,534,588 | 0.40% | |
| CORT |
Corcept Therapeutics Inc
Healthcare
|
NEW | 37,763 | $1,522,226 | 0.40% | |
| KYTX |
Kyverna Therapeutics, Inc.
Healthcare
|
Reduced | 173,106 | $1,493,904 | 0.39% | |
| PCRX |
Pacira BioSciences, Inc.
Healthcare
|
Reduced | 62,653 | $1,415,957 | 0.37% |