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ALNY

Alnylam Pharmaceuticals, Inc.
$323.50 +1.91 (+0.59%) At close · Jul 8
Market Cap
$41.48B
Shares
132,623,144

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$323.50 Open$318.50 Day$316.78–325.37 52W$273.11–495.55 Avg vol 30d1.2M Short int5.4M · 4.1% float · 4.8d Short vol60% Last earningsApr 30, 2026 DataJan 2020–Jul 2026 Filing10-Q · Apr 30
Equibles Rating blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Neutral Momentum Weak Sentiment Bearish Fundamentals Excellent Quant / Vol High
Market backdrop VIX 15.8 · calm Equity put/call 0.57
Technical
price trend
Neutral
50 / 200-day cross No cross
Price vs 200-day avg −11%
below
Price vs 50-day avg +9%
above
RSI (14) 69
neutral
MACD trend Positive
52-week position 23%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Weak
1-month return +11%
trailing
6-month return −13%
trailing
YTD return −19%
this year
Relative strength −20%
vs S&P · 6-mo
Sentiment
smart money
Bearish
Trend (MA cross) No cross
50d $297 › 200d $365 — 200d above 50d
Institutional flow Distributing
34 of 790 funds reported for Jun 30 · net -11.8K sh shares
Insider flow Distributing
Net -$1.1M over 90 days · 100% sells
Short interest Rising
4.10% of float · ▲ +2.6% MoM · 4.8 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
790 holders — mid 3-yr range
Squeeze score 69
elevated · 0–100
Fundamentals
Excellent
Revenue growth +23%
Y/Y
EPS growth +207%
Y/Y
Free cash flow $465.4M
Valuation P/E 134.2
rich
Balance sheet $981.6M
net cash
Quant / Vol
risk profile
High
Volatility 37%
annualized · 1-yr
Max drawdown −43%
past year
ATR 3.1%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Up next
Next earnings call
Aug 6, 2026 Est · unconfirmed · in 4 wks
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed Apr 30, 2026
AI Brief

TL;DR.

Bullish
    Bearish

      AI-generated from the earnings call and 8-K · may contain errors · not investment advice

      Guidance & track record
      Latest guidance · from the 8-K filed Apr 30, 2026
      Combined Net Product Revenues · 2026 Initiated $4.9B – $5.3B
      prior FY $3.71B midpoint +37.3% Y/Y
      Total TTR Net Product Revenues · 2026 Lowered $4.4B – $4.7B
      prior FY $3.71B midpoint +22.5% Y/Y

      Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

      Technicals

      trend & momentum for long-term holders Neutral
      1 · 4 · 2
      50 / 200-day cross
      No cross Neutral
      Price vs 200-day avg
      −11% Bearish
      Price vs 50-day avg
      +9% Bullish
      RSI (14)
      69 Neutral
      MACD trend
      Positive Bullish
      52-week position
      23% Neutral
      Volume (OBV)
      Confirms Neutral
      Market signals — smart money & positioning
      Bearish · 3 of 6
      Trend (MA cross) No cross
      50d $297 › 200d $365 — 200d above 50d
      Institutional flow Distributing
      34 of 790 funds reported for Jun 30 · net -11.8K sh shares
      Insider flow Distributing
      Net -$1.1M over 90 days · 100% sells
      Short interest Rising
      4.10% of float · ▲ +2.6% MoM · 4.8 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Steady
      790 holders — mid 3-yr range
      Price context
      position in its 52-week range
      52-wk low $273 Now $324 · 23% 52-wk high $496
      vs 200-day avg -11% vs 50-day avg +9%

      Illustrative technical + ownership context — a signal mix, not investment advice.

      Key metrics

      the company's own KPIs, from its earnings releases, calls, and filings
      Metric Latest Period YoY
      AMVUTTRA % Change 189% Three Months Ended December 31
      AMVUTTRA % Change At CER 187% Three Months Ended December 31
      Total Rare net product revenues 136,442K Three Months Ended December 31
      Total Rare net product revenues % Change 26% Three Months Ended December 31
      Total Rare net product revenues % Change At CER 23% Three Months Ended December 31
      Total TTR net product revenues 858,275K Three Months Ended December 31
      Total TTR net product revenues % Change 151% Three Months Ended December 31
      Total TTR net product revenues % Change At CER 149% Three Months Ended December 31

      Figures exactly as the company stated them · click a metric with a to chart its history · period links open the stating document · "call" marks figures stated on the earnings call, "filing" figures stated in the 10-K/10-Q · YoY needs the prior-year figure on file

      Versus peers

      Biotechnology — same industry group
      Open screener →
      Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
      ALNY
      Alnylam Pharmaceuticals, Inc.
      this stock
      $41.48B -18.6% +22.9% 134.2 4.1%
      ONC
      BeOne Medicines Ltd.
      $437.67B -0.6% +22179.2% 890.7 0.1%
      VRTX
      Vertex Pharmaceuticals Inc / Ma
      $126.01B +9.9% +46.2% 29.5 1.8%
      REGN
      Regeneron Pharmaceuticals, Inc.
      $70.03B -14.0% +20.8% 16.3 3.2%
      ARGX
      Argenx SE
      $56.84B +8.8% 2.4%

      Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

      At a glance

      key data from every section
      Ownership
      Institutional Holders Reducing
      Holders
      784
      % held
      93.5%
      Reported
      34 of 790
      Top holder
      FMR LLC
      Held Float
      View
      Held by Funds
      Fund positions
      726
      View
      Short & Settlement
      Short Interest Rising
      Shares short
      5.4M
      Days to cover
      4.8d
      Change
      +137.3K sh
      View
      Short Volume
      Short vol %
      60%
      As of
      Jul 9, 2026
      Short Total
      View
      Fails to Deliver
      FTD shares
      22.2K
      Value
      $6.4M
      As of
      Jun 12, 2026
      View
      Off-Exchange
      Off-exchange %
      41.9%
      Week of
      Jun 15, 2026
      Off-exch Lit
      View
      Smart Money
      Insider Trades Net selling
      Net (90d)
      -$1.1M
      Buyers / Sellers
      0 / 1
      Buyers Sellers
      View
      Congressional Trades Sell
      Member
      Jefferson Shreve
      Amount
      $15.0K–$50.0K
      Traded
      May 12, 2025
      View
      Financials
      Financials
      Revenue (FY)
      $3.7B
      Net income (FY)
      $313.7M
      EPS diluted
      $2.33
      View
      Filings
      SEC Filings
      Latest
      8-K
      Filed
      May 27, 2026
      This year
      8
      View
      Proposed Sales
      Value
      $1.1M
      Shares
      3.8K
      Filed
      Jun 1, 2026
      View
      Earnings & Events
      Earnings Calls
      Last call
      Jun 9, 2026
      View

      Performance

      5D 20D 120D MTD YTD
      ALNY +7.5% +10.7% -12.6% +7.5% -18.7%
      SPY -0.2% +0.8% +7.4% -0.2% +9.3%
      vs SPY +7.6% +9.9% -20.0% +7.6% -28.0%
      Key facts CIK 1178670 CUSIP 02043Q107 13F (30d) 54 filings 32 filers Visit website Investor relations