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VRTX

Vertex Pharmaceuticals Inc / Ma
$522.25 -7.34 (-1.39%) At close · Jul 7
Market Cap
$132.55B
Shares
253,805,417

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

The Jun 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out.
Holders: 1,699
Total Value: $102,878,952,593
Total Shares: 230,265,361
Showing 1–100 of 1,755 holdings by value · page 1 of 18

Institutional Ownership Trend

26 quarters

Superinvestors Holding VRTX

All superinvestors →
Tweedy Browne $18,034,410 Joel Greenblatt $9,326,880 Ray Dalio $5,964,434

Holder Concentration

Across 1,695 13F filers
Top Holder
11.0%
Jun 2023 → Mar 2026 · range 9.3% – 11.8%
of institutional value
Top 5
42.9%
Jun 2023 → Mar 2026 · range 37.2% – 42.9%
of institutional value
Top 10
54.3%
Jun 2023 → Mar 2026 · range 50.4% – 54.4%
of institutional value
HHI
445
Jun 2023 → Mar 2026 · range 359 – 445
Broadly held
Showing 100 of 1,755
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega Capital World Investors $11,327,882,090 11.01% 25,368,124
Mega BlackRock, Inc. $10,703,348,112 10.40% 23,969,517
Mega Capital Research Global Investors $9,433,587,964 9.17% 21,125,964
Mega VANGUARD CAPITAL MANAGEMENT LLC $7,373,630,177 7.17% 16,512,810
Mega STATE STREET CORP $5,237,976,269 5.09% 11,730,139
Mega JPMORGAN CHASE & CO $3,140,585,469 3.05% 7,033,156
Mega GEODE CAPITAL MANAGEMENT, LLC $2,741,586,360 2.66% 6,139,621
Mega Capital International Investors $2,288,998,423 2.22% 5,126,077
Large LOOMIS SAYLES & CO L P $1,787,866,229 1.74% 4,003,821
Mega ALLIANCEBERNSTEIN L.P. $1,746,322,380 1.70% 3,910,786
Mega WELLINGTON MANAGEMENT GROUP LLP $1,434,549,489 1.39% 3,212,589
Mega MORGAN STANLEY $1,423,962,911 1.38% 3,188,881
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $1,365,249,602 1.33% 3,057,396
Mega BANK OF AMERICA CORP /DE/ Bank $1,285,223,834 1.25% 2,878,183
Mega JENNISON ASSOCIATES LLC $1,223,545,945 1.19% 2,740,059
Mega Clearbridge Investments, LLC $1,206,093,376 1.17% 2,700,975
Mega AMERIPRISE FINANCIAL INC $1,175,954,602 1.14% 2,633,481
Mega NORTHERN TRUST CORP Bank $1,145,046,441 1.11% 2,564,264
Mega Invesco Ltd. $1,143,614,384 1.11% 2,561,057
Mega GOLDMAN SACHS GROUP INC $1,079,677,898 1.05% 2,417,875
Mega JANUS HENDERSON GROUP PLC $951,812,064 0.93% 2,131,527
Mega FMR LLC $902,129,131 0.88% 2,020,265
Mega Legal & General Group Plc $873,326,855 0.85% 1,955,764
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $857,745,736 0.83% 1,920,871
Mega VICTORY CAPITAL MANAGEMENT INC $843,300,167 0.82% 1,888,521
Mega PRICE T ROWE ASSOCIATES INC /MD/ $785,964,877 0.76% 1,760,122
Mega Bank of New York Mellon Corp Bank $708,403,098 0.69% 1,586,427
Mega DEUTSCHE BANK AG\ Bank $686,660,626 0.67% 1,537,736
Mega Amundi $657,528,360 0.64% 1,472,496
Mega VANGUARD FIDUCIARY TRUST CO Bank $654,504,394 0.64% 1,465,724
Large WCM INVESTMENT MANAGEMENT, LLC $500,723,610 0.49% 1,121,341
Mega ROYAL BANK OF CANADA Bank $496,494,870 0.48% 1,111,871
Mega Nuveen, LLC $484,270,396 0.47% 1,084,495
Mega DIMENSIONAL FUND ADVISORS LP $441,780,774 0.43% 989,342
Large EDGEWOOD MANAGEMENT LLC $404,176,303 0.39% 905,129
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. $378,686,906 0.37% 848,047
Large Assenagon Asset Management S.A. $377,298,225 0.37% 759,564
Mega AMERICAN CENTURY COMPANIES INC $363,164,283 0.35% 813,285
Mega WELLS FARGO & COMPANY/MN $332,670,066 0.32% 744,995
Mega Swiss National Bank Bank $332,493,684 0.32% 744,600
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $313,649,696 0.30% 702,400
Mega CITIGROUP INC $304,900,636 0.30% 682,807
Mid Bellevue Group AG $304,499,197 0.30% 681,908
Mega BARCLAYS PLC $296,173,457 0.29% 663,263
Mega HSBC HOLDINGS PLC $292,681,510 0.28% 655,443
Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $285,316,733 0.28% 638,950
Mega UBS Group AG $281,596,158 0.27% 630,618
Mega Sumitomo Mitsui Trust Group, Inc. $274,375,609 0.27% 614,448
Mega Mitsubishi UFJ Asset Management Co., Ltd. $266,806,310 0.26% 597,497
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $250,553,594 0.24% 561,100
Mega Vanguard Global Advisers, LLC $248,157,013 0.24% 555,733
Large NATIXIS ADVISORS, LLC $247,393,876 0.24% 554,024
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $247,045,129 0.24% 553,243
Mega NEUBERGER BERMAN GROUP LLC $246,276,633 0.24% 551,522
Mega FRANKLIN RESOURCES INC $246,102,477 0.24% 551,132
Mega National Pension Service Pension $237,590,091 0.23% 532,069
Large VOYA INVESTMENT MANAGEMENT LLC $235,347,566 0.23% 527,047
Large B. Metzler seel. Sohn & Co. AG $228,198,014 0.22% 511,036
Large DekaBank Deutsche Girozentrale Bank $226,153,308 0.22% 506,457
Mega ENVESTNET ASSET MANAGEMENT INC $224,861,468 0.22% 503,564
Mega California Public Employees Retirement System Pension $224,776,625 0.22% 503,374
Mega RAYMOND JAMES FINANCIAL INC $198,485,243 0.19% 444,496
Mega VANGUARD ASSET MANAGEMENT, Ltd $197,449,717 0.19% 442,177
Large Life Cycle Investment Partners Ltd $196,660,234 0.19% 440,409
Mega PRINCIPAL FINANCIAL GROUP INC $190,459,579 0.19% 426,523
Mega RHUMBLINE ADVISERS $188,948,935 0.18% 423,140
Large RENAISSANCE TECHNOLOGIES LLC $188,300,559 0.18% 421,688
Mega BNP PARIBAS ARBITRAGE, SA $185,593,187 0.18% 415,625
Large Chevy Chase Trust Holdings, LLC $182,016,401 0.18% 407,615
Large Robeco Institutional Asset Management B.V. $179,350,111 0.17% 401,644
Mega BANK OF MONTREAL /CAN/ Bank $174,363,150 0.17% 390,476
Mega TWO SIGMA INVESTMENTS, LP $168,857,314 0.16% 378,146
Large Zurcher Kantonalbank (Zurich Cantonalbank) Bank $168,351,385 0.16% 377,013
Large ProShare Advisors LLC $166,796,979 0.16% 373,532
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $166,774,205 0.16% 373,481
Large Russell Investments Group, Ltd. $164,188,731 0.16% 367,691
Mega DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main Bank $162,769,634 0.16% 364,513
Mega CITADEL ADVISORS LLC $151,510,128 0.15% 339,298
Large Universal- Beteiligungs- und Servicegesellschaft mbH $151,085,469 0.15% 338,347
Large Pictet Asset Management Holding SA $150,738,061 0.15% 337,569
Mega MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $146,240,953 0.14% 327,498
Large Bank Julius Baer & Co. Ltd, Zurich Bank $141,734,475 0.14% 317,406
Large MARSHALL WACE, LLP $141,579,078 0.14% 317,058
Mid Harding Loevner LP $140,010,830 0.14% 313,546
Large AMF Tjanstepension AB Pension $139,729,957 0.14% 312,917
Large PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO Pension $139,208,845 0.14% 311,750
Mega FIRST TRUST ADVISORS LP $136,847,094 0.13% 306,461
Large Cerity Partners LLC $132,467,876 0.13% 296,654
Large NEW YORK STATE COMMON RETIREMENT FUND Pension $130,574,547 0.13% 292,414
Large NATIONAL BANK OF CANADA /FI/ Bank $121,511,122 0.12% 272,117
Large Swedbank AB Bank $121,259,276 0.12% 271,553
Mega LPL Financial LLC $119,700,405 0.12% 268,062
Large ROYAL LONDON ASSET MANAGEMENT LTD $112,613,815 0.11% 252,192
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $112,523,614 0.11% 251,990
Large Connor, Clark & Lunn Investment Management Ltd. $112,399,029 0.11% 251,711
Mega D. E. Shaw & Co., Inc. $111,170,598 0.11% 248,960
Large Man Group plc $105,739,778 0.10% 236,798
Large Aberdeen Group plc $104,258,157 0.10% 233,480
Large Candriam S.C.A. $102,219,704 0.10% 228,915
Mega TD Asset Management Inc $101,898,194 0.10% 228,195
Key facts CIK 875320 CUSIP 92532F100 13F (30d) 102 filings 60 filers Visit website Investor relations

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