Large
Aberdeen Group plc
1
$12,670,920
9.52%
824,393
6.042%
-1
-0.0%
Shares
2026-07-31
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
abrdn Inc.
824,393
$12,670,920
100.0%
Defined
Mid
BVF INC/IL
1
$11,762,584
8.84%
765,295
5.609%
-2
-0.0%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
BVF PARTNERS L P/IL
765,295
$11,762,584
100.0%
Defined
Mega
MILLENNIUM MANAGEMENT LLC
$11,379,133
8.55%
740,347
5.426%
+362,355
+95.9%
Shares
2026-08-14
Small
Avidity Partners Management LP
$10,296,993
7.74%
669,941
4.910%
+602,947
+900.0%
Shares
2026-08-14
Mid
BRAIDWELL LP
$9,913,803
7.45%
645,010
4.727%
New
Shares
2026-08-14
Mid
Laurion Capital Management LP
$9,380,710
7.05%
610,326
4.473%
+222,110
+57.2%
Shares
2026-08-13
Mega
VANGUARD CAPITAL MANAGEMENT LLC
$8,784,892
6.60%
571,561
4.189%
+57,729
+11.2%
Shares
2026-08-13
Small
Jones Hill Capital LP
$8,296,941
6.24%
539,814
3.956%
New
Shares
2026-08-13
Large
Woodline Partners LP
$7,247,385
5.45%
471,528
3.456%
+374,813
+387.5%
Shares
2026-08-14
Mid
Soleus Capital Management, L.P.
$6,916,500
5.20%
450,000
3.298%
0
0.0%
Shares
2026-08-11
Small
Propel Bio Management, LLC
1
$4,995,588
3.75%
325,022
2.382%
+90,544
+38.6%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Mid
Nantahala Capital Management, LLC
$3,852,429
2.90%
250,646
1.837%
-3
-0.0%
Shares
2026-08-19
Mega
UBS Group AG
2
$2,701,369
2.03%
175,756
1.288%
+123,476
+236.2%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
UBS AG
164,671
$2,530,993
93.7%
Defined
UBS Switzerland AG
11,085
$170,376
6.3%
Defined
Mega
GEODE CAPITAL MANAGEMENT, LLC
2
$2,623,274
1.97%
170,675
1.251%
+18,098
+11.9%
Shares
2026-08-12
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC
27,666
$425,226
16.2%
Defined
Held directly
143,009
$2,198,048
83.8%
Defined
Mid
683 Capital Management, LLC
1
$2,263,155
1.70%
147,245
1.079%
-97,755
-39.9%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
683 Capital Partners, LP
147,245
$2,263,155
100.0%
Defined
Large
ADAGE CAPITAL PARTNERS GP, L.L.C.
$2,149,648
1.62%
139,860
1.025%
0
0.0%
Shares
2026-08-14
Mega
BlackRock, Inc.
5
$2,040,995
1.53%
132,791
0.973%
+36,368
+37.7%
Shares
2026-08-07
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE
21,011
$322,939
15.8%
Sole
BlackRock Investment Management, LLC
3,121
$47,969
2.4%
Sole
BlackRock Fund Advisors
46,243
$710,754
34.8%
Sole
BlackRock Institutional Trust Company, N.A.
61,013
$937,769
45.9%
Sole
BlackRock (Luxembourg) S.A.
1,403
$21,564
1.1%
Sole
Mega
SUSQUEHANNA INTERNATIONAL GROUP, LLP
1
$1,819,808
1.37%
118,400
0.868%
+112,940
+2068.5%
Call
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Large
MARSHALL WACE, LLP
1
$1,611,021
1.21%
104,816
0.768%
+9,519
+10.0%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Mega
SUSQUEHANNA INTERNATIONAL GROUP, LLP
1
$1,396,979
1.05%
90,890
0.666%
-11,936
-11.6%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Mega
JANE STREET GROUP, LLC
2
$1,378,488
1.04%
89,687
0.657%
+23,772
+36.1%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Jane Street Capital, LLC
73,177
$1,124,730
81.6%
Defined
Jane Street Global Trading, LLC
16,510
$253,758
18.4%
Defined
Large
Jefferies Financial Group Inc.
1
$1,304,913
0.98%
84,900
0.622%
New
Shares
2026-08-17
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
JEFFERIES LLC
joint
84,900
$1,304,913
100.0%
Defined
Mega
VANGUARD FIDUCIARY TRUST CO
Bank
$1,260,785
0.95%
82,029
0.601%
+7,975
+10.8%
Shares
2026-08-13
Small
Ikarian Capital, LLC
$1,036,921
0.78%
67,464
0.494%
-2
-0.0%
Shares
2026-08-14
Mega
SUSQUEHANNA INTERNATIONAL GROUP, LLP
1
$774,648
0.58%
50,400
0.369%
+48,330
+2334.8%
Put
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Large
Quadrature Capital Ltd
1
$580,770
0.44%
37,786
0.277%
+34,823
+1175.3%
Shares
2026-08-07
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Quadrature US Inc.
37,786
$580,770
100.0%
Other
Small
Simplify Asset Management Inc.
$472,243
0.35%
30,725
0.225%
-13,168
-30.0%
Shares
2026-07-16
Mega
NORTHERN TRUST CORP
Bank
1
$472,166
0.35%
30,720
0.225%
+4,387
+16.7%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
NORTHERN TRUST CO
joint
30,720
$472,166
100.0%
Defined
Mega
MORGAN STANLEY
2
$365,006
0.27%
23,748
0.174%
-305,106
-92.8%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
MORGAN STANLEY CAPITAL SERVICES, LLC
21,923
$336,956
92.3%
Defined
MORGAN STANLEY SMITH BARNEY LLC
1,825
$28,050
7.7%
Defined
Mid
Brevan Howard Capital Management LP
1
$356,291
0.27%
23,181
0.170%
+18,597
+405.7%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Brevan Howard US Investment Management, LP
23,181
$356,291
100.0%
Defined
Mega
BNP PARIBAS ARBITRAGE, SA
$352,111
0.26%
22,909
0.168%
+10,724
+88.0%
Shares
2026-08-13
Mega
CITADEL ADVISORS LLC
1
$332,299
0.25%
21,620
0.158%
+10,171
+88.8%
Shares
2026-09-02
This filing is a combination report: the position is filed across the managers below.
Large
Belvedere Trading LLC
$321,233
0.24%
20,900
0.153%
New
Call
2026-07-31
Mega
LPL Financial LLC
$268,068
0.20%
17,441
0.128%
+511
+3.0%
Shares
2026-08-07
Mega
JANE STREET GROUP, LLC
1
$235,161
0.18%
15,300
0.112%
+2,050
+15.5%
Call
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Jane Street Capital, LLC
15,300
$235,161
100.0%
Defined
Large
MML INVESTORS SERVICES, LLC
$225,354
0.17%
14,662
0.107%
+5,599
+61.8%
Shares
2026-08-07
Large
ALPS ADVISORS INC
$212,474
0.16%
13,824
0.101%
New
Shares
2026-07-29
Mega
CITADEL ADVISORS LLC
1
$211,491
0.16%
13,760
0.101%
+2,200
+19.0%
Call
2026-09-02
This filing is a combination report: the position is filed across the managers below.
Mid
BOOTHBAY FUND MANAGEMENT, LLC
$200,686
0.15%
13,057
0.096%
New
Shares
2026-08-14
Large
Point72 Asset Management, L.P.
$166,088
0.12%
10,806
0.079%
New
Shares
2026-08-14
Small
Strategies Wealth Advisors, LLC
$153,700
0.12%
10,000
0.073%
0
0.0%
Shares
2026-08-14
Mid
China Universal Asset Management Co., Ltd.
$98,368
0.07%
6,400
0.047%
New
Shares
2026-07-24
Mega
CITIGROUP INC
1
$70,225
0.05%
4,569
0.033%
New
Shares
2026-08-03
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Citigroup Financial Products Inc.
joint
4,569
$70,225
100.0%
Defined
Mega
Vanguard Global Advisers, LLC
$48,968
0.04%
3,186
0.023%
-1
-0.0%
Shares
2026-08-13
Mega
ROYAL BANK OF CANADA
Bank
1
$15,370
0.01%
1,000
0.007%
+699
+232.2%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
RBC Capital Markets, LLC
1,000
$15,370
100.0%
Defined
Large
OSAIC HOLDINGS, INC.
1
$15,370
0.01%
1,000
0.007%
-1,000
-50.0%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
OSAIC WEALTH, INC.
1,000
$15,370
100.0%
Defined
Small
Providence Capital Advisors, LLC
$10,482
0.01%
682
0.005%
New
Shares
2026-08-11
Mega
BARCLAYS PLC
1
$7,592
0.01%
494
0.004%
+251
+103.3%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
BARCLAYS CAPITAL INC.
494
$7,592
100.0%
Defined
Mid
SBI Securities Co., Ltd.
Broker-Dealer
$5,733
0.00%
373
0.003%
-4
-1.1%
Shares
2026-07-23
Large
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO
$2,305
0.00%
150
0.001%
-1
-0.7%
Shares
2026-08-12
Mid
GROUP ONE TRADING LLC
$2,228
0.00%
145
0.001%
-25
-14.7%
Shares
2026-08-14
Mega
FMR LLC
2
$1,966
0.00%
128
0.001%
+82
+178.3%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Fidelity Management & Research Co LLC
107
$1,644
83.6%
Defined
STRATEGIC ADVISERS LLC
21
$322
16.4%
Defined
Large
Rockefeller Capital Management L.P.
1
$1,537
0.00%
100
0.001%
0
0.0%
Shares
2026-08-13
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
ROCKEFELLER FINANCIAL LLC
100
$1,537
100.0%
Defined
Mega
WELLS FARGO & COMPANY/MN
2
$1,336
0.00%
87
0.001%
-3
-3.3%
Shares
2026-08-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC
85
$1,306
97.8%
Defined
WELLS FARGO CLEARING SERVICES, LLC
2
$30
2.2%
Defined
Mid
Allworth Financial LP
$1,291
0.00%
84
0.001%
New
Shares
2026-08-11
Mega
JPMORGAN CHASE & CO
1
$584
0.00%
38
0.000%
-3
-7.3%
Shares
2026-08-12
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
J.P. Morgan Securities plc
38
$584
100.0%
Defined
Small
SHP Wealth Management
$215
0.00%
14
0.000%
0
0.0%
Shares
2026-08-11
Small
CALDWELL SUTTER CAPITAL, INC.
$153
0.00%
10
0.000%
+10
Shares
2026-08-05
Small
Caitong International Asset Management Co., Ltd
$30
0.00%
2
0.000%
+2
Shares
2026-08-05
Large
DANSKE BANK A/S
Bank
$30
0.00%
2
0.000%
New
Shares
2026-08-10
Large
RENAISSANCE TECHNOLOGIES LLC
$1,020,272
0.77%
919,164
0.674%
Sold Out
Shares
2026-05-14
Mega
STATE STREET CORP
1
$627,865
0.47%
565,645
0.415%
Sold Out
Shares
2026-05-15
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
STATE STREET GLOBAL ADVISORS TRUST COMPANY
565,645
$627,865
100.0%
Defined
Large
HRT FINANCIAL LP
$547,666
0.41%
493,393
0.362%
Sold Out
Shares
2026-05-14
Large
Hudson Bay Capital Management LP
1
$236,448
0.18%
213,017
0.156%
Sold Out
Shares
2026-05-13
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Hudson Bay Capital UK LLP
213,017
$236,448
100.0%
Defined
Large
OMERS ADMINISTRATION Corp
$186,813
0.14%
168,300
0.123%
Sold Out
Shares
2026-05-15
Mega
GOLDMAN SACHS GROUP INC
1
$166,244
0.12%
149,770
0.110%
Sold Out
Shares
2026-05-15
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
GOLDMAN SACHS & CO. LLC
149,770
$166,244
100.0%
Defined
Mega
BANK OF AMERICA CORP /DE/
Bank
1
$159,692
0.12%
143,867
0.105%
Sold Out
Shares
2026-05-18
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
BOFA SECURITIES, INC.
143,867
$159,692
100.0%
Defined
Mid
Virtu Financial LLC
1
$125,836
0.09%
113,366
0.083%
Sold Out
Shares
2026-05-14
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Virtu Americas LLC
113,366
$125,836
100.0%
Defined
Mega
Qube Research & Technologies Ltd
$123,720
0.09%
111,460
0.082%
Sold Out
Shares
2026-05-15
Mid
HB Wealth Management, LLC
$101,509
0.08%
91,450
0.067%
Sold Out
Shares
2026-04-27
Mega
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
$94,350
0.07%
85,000
0.062%
Sold Out
Shares
2026-05-15
Mega
TWO SIGMA INVESTMENTS, LP
$74,576
0.06%
67,186
0.049%
Sold Out
Shares
2026-05-15
Large
Cambridge Investment Research Advisors, Inc.
$53,835
0.04%
48,500
0.036%
Sold Out
Shares
2026-04-30
Large
Creative Planning
$38,874
0.03%
35,022
0.026%
Sold Out
Shares
2026-05-12
Mid
Graham Capital Management, L.P.
$36,959
0.03%
33,297
0.024%
Sold Out
Shares
2026-05-15
Mid
Tower Research Capital LLC (TRC)
1
$36,483
0.03%
32,868
0.024%
Sold Out
Shares
2026-05-15
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
Latour Trading LLC (Latour)
32,868
$36,483
100.0%
Defined
Mid
XTX Topco Ltd
1
$34,214
0.03%
30,824
0.023%
Sold Out
Shares
2026-05-15
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
XTX EXECUTION SERVICES LLC
joint
30,824
$34,214
100.0%
Defined
Mid
ADAR1 Capital Management, LLC
$33,300
0.03%
30,000
0.022%
Sold Out
Shares
2026-05-18
Mega
Bank of New York Mellon Corp
Bank
3
$31,476
0.02%
28,358
0.021%
Sold Out
Shares
2026-05-05
This filing is a combination report: the position is filed across the managers below.
Manager
Shares
Value (USD)
% of position
Discretion
The Bank of New York Mellon
13,862
$15,386
48.9%
Defined
Newton Investment Management North America, LLC
14,495
$16,089
51.1%
Defined
Held directly
1
$1
0.0%
Defined
Large
Schonfeld Strategic Advisors LLC
$31,413
0.02%
28,300
0.021%
Sold Out
Shares
2026-05-15
Small
Scientech Research LLC
$29,564
0.02%
26,635
0.020%
Sold Out
Shares
2026-05-15
Micro
CTC Alternative Strategies, Ltd.
$27,072
0.02%
24,390
0.018%
Sold Out
Shares
2026-05-21
Large
Corient Private Wealth LLC
$24,531
0.02%
22,100
0.016%
Sold Out
Shares
2026-05-15
Small
LINCOLN CAPITAL CORP
$22,644
0.02%
20,400
0.015%
Sold Out
Shares
2026-04-16
Small
AXQ CAPITAL, LP
$20,147
0.02%
18,151
0.013%
Sold Out
Shares
2026-05-13
Small
Balboa Wealth Partners
$13,320
0.01%
12,000
0.009%
Sold Out
Shares
2026-04-16
Mid
Baader Bank Aktiengesellschaft
Bank
$12,521
0.01%
11,281
0.008%
Sold Out
Shares
2026-05-08
Large
COMMONWEALTH EQUITY SERVICES, LLC
$11,499
0.01%
10,360
0.008%
Sold Out
Shares
2026-04-27
Mid
Private Advisor Group, LLC
$11,100
0.01%
10,000
0.007%
Sold Out
Shares
2026-04-27
Small
Crescent Grove Advisors, LLC
$11,100
0.01%
10,000
0.007%
Sold Out
Shares
2026-05-06
Mid
Dynamic Advisor Solutions LLC
$11,100
0.01%
10,000
0.007%
Sold Out
Shares
2026-04-08
Large
CWM, LLC
$9,592
0.01%
8,642
0.006%
Sold Out
Shares
2026-05-14
Mid
Smartleaf Asset Management LLC
$23
0.00%
21
0.000%
Sold Out
Shares
2026-05-15
Mid
Parallel Advisors, LLC
$2
0.00%
2
0.000%
Sold Out
Shares
2026-05-07
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