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FULC

Fulcrum Therapeutics, Inc.
$3.72 -0.12 (-3.13%) At close · Jul 6
Market Cap
$247.88M
Shares
66,633,321

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 168
Total Value: $550,944,475
Total Shares: 71,831,105
Showing 1–100 of 174 holdings by value · page 1 of 2

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 168 13F filers · Δ vs Dec 31, 2025
Top Holder
9.1%
Jun 2023 → Mar 2026 · range 9.1% – 20.6%
−0.5 pts
Top 5
36.7%
Jun 2023 → Mar 2026 · range 36.7% – 58.5%
−2.2 pts
Top 10
54.2%
Jun 2023 → Mar 2026 · range 54.2% – 78.1%
−3.7 pts
HHI
416
Jun 2023 → Mar 2026 · range 416 – 878
Broadly held−29

Quarterly Activity

vs Dec 31, 2025
New
36
Increased
73
Decreased
39
Sold Out
40
Unchanged
20
Holder count: -4
Institutional value: -28.3%
Shares held: +5.8%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Large Balyasny Asset Management L.P. +1,209,507 2,179,946
Mega BlackRock, Inc. +1,126,832 5,390,593
Large Aberdeen Group plc +957,926 2,211,953
Large Qube Research & Technologies Ltd +582,250 974,739
Mega STATE STREET CORP +544,506 1,549,851

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Large ADAGE CAPITAL PARTNERS GP, L.L.C. −1,300,000 400,000
Mid Nantahala Capital Management, LLC −1,243,306 3,050,040
Mid ADAR1 Capital Management, LLC −1,188,189 130,560
Mid Ikarian Capital, LLC −326,311 1,049,161
Large Point72 Asset Management, L.P. −323,377 2,074,855

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 2,692,948 $20,654,911
Small Jones Hill Capital LP 1,771,926 $13,590,672
Large Alyeska Investment Group, L.P. 1,328,449 $10,189,203
Large Assenagon Asset Management S.A. 1,193,873 $9,157,005
Mega VANGUARD FIDUCIARY TRUST CO 329,884 $2,530,210

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 3,559,552 $40,258,532
Small GREAT POINT PARTNERS LLC 800,000 $9,048,000
Small Sio Capital Management, LLC 382,000 $4,320,420
Large Driehaus Capital Management LLC 243,388 $2,752,718
Small Catalio Capital Management, LP 201,301 $2,276,714
Filter: New 36 Increased 73 Reduced 39 Sold out 40 Unchanged 20
Showing 100 of 174
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
Mid SUVRETTA CAPITAL MANAGEMENT, LLC $50,323,721 9.13% 6,561,111
Mid RA CAPITAL MANAGEMENT, L.P. $46,433,873 8.43% 6,053,960
Mega BlackRock, Inc. $41,345,844 7.50% 5,390,593
Mid TCG Crossover Management, LLC $40,267,500 7.31% 5,250,000
Mid BRAIDWELL LP $24,044,851 4.36% 3,134,922
Mid Nantahala Capital Management, LLC $23,393,806 4.25% 3,050,040
Mega VANGUARD CAPITAL MANAGEMENT LLC $20,654,911 3.75% 2,692,948
Mid Siren, L.L.C. $18,024,500 3.27% 2,350,000
Small First Turn Management, LLC $17,304,356 3.14% 2,256,109
Large Aberdeen Group plc $16,965,679 3.08% 2,211,953
Large Point72 Asset Management, L.P. $15,914,137 2.89% 2,074,855
Small GSK plc $13,696,426 2.49% 1,785,714
Large Balyasny Asset Management L.P. $13,652,185 2.48% 1,779,946
Small Jones Hill Capital LP $13,590,672 2.47% 1,771,926
Mega D. E. Shaw & Co., Inc. $12,450,565 2.26% 1,623,281
Mega STATE STREET CORP $11,887,357 2.16% 1,549,851
Mega GEODE CAPITAL MANAGEMENT, LLC $11,401,776 2.07% 1,486,542
Large Alyeska Investment Group, L.P. $10,189,203 1.85% 1,328,449
Mega CITADEL ADVISORS LLC $9,913,366 1.80% 1,292,486
Large Assenagon Asset Management S.A. $9,157,005 1.66% 1,193,873
Mega DIMENSIONAL FUND ADVISORS LP $8,669,253 1.57% 1,130,281
Mid Vestal Point Capital, LP $8,437,000 1.53% 1,100,000
Mid Ikarian Capital, LLC $8,047,064 1.46% 1,049,161
Large Qube Research & Technologies Ltd $7,476,248 1.36% 974,739
Large Connor, Clark & Lunn Investment Management Ltd. $5,650,366 1.03% 736,684
Large ACADIAN ASSET MANAGEMENT LLC $5,578,506 1.01% 727,315
Mega GOLDMAN SACHS GROUP INC $4,386,541 0.80% 571,909
Mega AQR CAPITAL MANAGEMENT LLC $4,166,072 0.76% 543,165
Mega NORTHERN TRUST CORP Bank $3,627,793 0.66% 472,985
Large Trexquant Investment LP $3,478,567 0.63% 453,529
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $3,274,085 0.59% 426,869
Small SILVERARC CAPITAL MANAGEMENT, LLC $3,221,008 0.58% 419,949
Large Balyasny Asset Management L.P. $3,068,000 0.56% 400,000
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $3,068,000 0.56% 400,000
Mid Jump Financial, LLC $2,836,403 0.51% 369,805
Mega MILLENNIUM MANAGEMENT LLC $2,734,132 0.50% 356,471
Mega VANGUARD FIDUCIARY TRUST CO Bank $2,530,210 0.46% 329,884
Mega UBS Group AG $2,417,468 0.44% 315,185
Mega JANE STREET GROUP, LLC $2,380,897 0.43% 310,417
Mid BOOTHBAY FUND MANAGEMENT, LLC $2,331,587 0.42% 303,988
Large BESSEMER GROUP INC $2,201,197 0.40% 286,988
Large PANAGORA ASSET MANAGEMENT INC $1,868,143 0.34% 243,565
Small DAFNA Capital Management LLC $1,572,350 0.29% 205,000
Large Squarepoint Ops LLC $1,349,490 0.24% 175,944
Mega MORGAN STANLEY $1,329,492 0.24% 173,337
Mega AMERICAN CENTURY COMPANIES INC $1,198,376 0.22% 156,242
Large STATE OF WISCONSIN INVESTMENT BOARD $1,184,516 0.21% 154,435
Mid Y-Intercept (Hong Kong) Ltd $1,176,148 0.21% 153,344
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,150,500 0.21% 150,000
Mega Bank of New York Mellon Corp Bank $1,150,053 0.21% 149,942
Mega TWO SIGMA INVESTMENTS, LP $1,066,130 0.19% 139,000
Mid GSA CAPITAL PARTNERS LLP $1,048,212 0.19% 136,664
Mid Fiduciary Trust Co Bank $1,047,376 0.19% 136,555
Mid ADAR1 Capital Management, LLC $1,001,395 0.18% 130,560
Mega Nuveen, LLC $994,170 0.18% 129,618
Mega BANK OF AMERICA CORP /DE/ Bank $970,707 0.18% 126,559
Mid Engineers Gate Manager LP $967,256 0.18% 126,109
Mega WELLINGTON MANAGEMENT GROUP LLP $909,661 0.17% 118,600
Small Simplify Asset Management Inc. $889,673 0.16% 115,994
Mega Invesco Ltd. $852,328 0.15% 111,125
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $777,247 0.14% 101,336
Mega BARCLAYS PLC $678,472 0.12% 88,458
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $641,979 0.12% 83,700
Mega PRICE T ROWE ASSOCIATES INC /MD/ $614,896 0.11% 80,169
Large Russell Investments Group, Ltd. $607,130 0.11% 79,157
Mid XTX Topco Ltd $549,195 0.10% 71,603
Mid RBF Capital, LLC $536,900 0.10% 70,000
Mid Atom Investors LP $530,418 0.10% 69,155
Mega RHUMBLINE ADVISERS $507,562 0.09% 66,175
Large Creative Planning $491,562 0.09% 64,089
Mega FMR LLC $468,184 0.08% 61,041
Mega HSBC HOLDINGS PLC $449,738 0.08% 58,636
Mega FRANKLIN RESOURCES INC $419,288 0.08% 54,666
Mid GROUP ONE TRADING LLC $412,308 0.07% 53,756
Mid Burkehill Global Management, LP $383,500 0.07% 50,000
Large STRS OHIO $378,131 0.07% 49,300
Mega DEUTSCHE BANK AG\ Bank $374,510 0.07% 48,828
Large Man Group plc $353,732 0.06% 46,119
Small EntryPoint Capital, LLC $347,052 0.06% 45,248
Mid Graham Capital Management, L.P. $327,823 0.06% 42,741
Large Marex Group plc $322,140 0.06% 42,000
Mid SIMPLEX TRADING, LLC $321,679 0.06% 41,940
Large COMMONWEALTH EQUITY SERVICES, LLC $309,024 0.06% 40,290
Mid BIT Capital GmbH $306,800 0.06% 40,000
Small Matisse Capital $304,107 0.06% 39,649
Mid Brevan Howard Capital Management LP $302,535 0.05% 39,444
Mega Vanguard Global Advisers, LLC $295,440 0.05% 38,519
Small Seven Fleet Capital Management LP $292,227 0.05% 38,100
Mega CITADEL ADVISORS LLC $285,324 0.05% 37,200
Mega ALLIANCEBERNSTEIN L.P. $265,151 0.05% 34,570
Large MetLife Investment Management, LLC $254,367 0.05% 33,164
Mid ALGERT GLOBAL LLC $253,493 0.05% 33,050
Large Woodline Partners LP $236,182 0.04% 30,793
Mid COUNTRY TRUST BANK Bank $230,414 0.04% 30,041
Large LMR Partners LLP $230,100 0.04% 30,000
Mega JPMORGAN CHASE & CO $228,504 0.04% 29,792
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Mutual Fund $215,373 0.04% 28,080
Mid Pale Fire Capital SE $200,187 0.04% 26,100
Large Quantinno Capital Management LP $196,881 0.04% 25,669
Mega CITIGROUP INC $179,746 0.03% 23,435
Key facts CIK 1680581 CUSIP 359616109 13F (30d) 3 filings 3 filers Visit website Investor relations

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