PLRX · Pliant Therapeutics, Inc. · Holdings
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 86 13F filersWho Holds PLRX
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 86 filers, like-for-like change -3.2%; actively managed books -2.9%; index-like books -5.5%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 56.6% | 39 | +15.3% |
| Exempt adviser | 5.0% | 3 | -6.3% |
| Adviser | 0.4% | 4 | -93.5% |
| Bank | 3.4% | 9 | -38.8% |
| Benefit plan | 0.1% | 1 | 0.0% |
| Non-US | 0.0% | 3 | 0.0% |
| Holding company | 3.7% | 5 | -23.3% |
| Broker-dealer | 0.0% | 0 | — |
| Insurer | 0.0% | 0 | — |
| Unknown | 30.8% | 22 | -2.8% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 11.4% | 11 | -5.5% |
| Systematic-like | 16.9% | 13 | -22.4% |
| Concentrated | 30.5% | 12 | -8.1% |
| Diversified active | 41.3% | 50 | +13.6% |
| Not measured | 0.0% | 0 | — |
| Unknown | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 11.0% | 33 | -14.6% |
| Medium turnover | 53.9% | 23 | +5.9% |
| High turnover | 27.8% | 23 | -15.2% |
| Unknown | 7.3% | 7 | +8.7% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 9.9% | 13 | -38.4% |
| Medium horizon | 33.1% | 13 | +46.6% |
| Long horizon | 31.4% | 48 | -18.5% |
| Unknown | 25.6% | 12 | -1.8% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 22.8% | 19 | -0.4% |
| $1B to $10B | 33.2% | 18 | +17.5% |
| $10B to $100B | 18.0% | 22 | -6.5% |
| $100B or more | 26.0% | 27 | -20.9% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Individuals and high net worth | 0.6% | 8 | +5.5% |
| Pooled investment vehicles | 41.6% | 20 | +20.0% |
| Registered funds and BDCs | 8.0% | 5 | +7.2% |
| Governments and sovereign funds | 3.0% | 2 | +4.1% |
| Diversified | 3.0% | 3 | -3.7% |
| Other investment advisers | 0.0% | 0 | -100.0% |
| Pension and profit sharing plans | 0.0% | 0 | — |
| Insurance companies | 0.0% | 0 | — |
| Unknown | 43.9% | 48 | -19.7% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 50.0% | 26 | +14.9% |
| Other private funds | 1.6% | 4 | +4.9% |
| Mixed private funds | 0.0% | 0 | — |
| No private funds | 9.9% | 12 | +6.3% |
| Real estate funds | 0.0% | 0 | -100.0% |
| Private equity funds | 0.0% | 0 | — |
| Private funds, type not stated | 0.0% | 0 | — |
| Venture capital funds | 0.0% | 0 | — |
| Securitized asset funds | 0.0% | 0 | — |
| Unknown | 38.4% | 44 | -21.4% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 90.5% | 72 | -1.4% |
| Outside the US | 9.5% | 14 | -17.5% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Excluded 1 holder with no observed 2026-03-31 13F and 1 holder with no observed 2026-06-30 13F.
Conviction and Crowding
86 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $27,508 (1 buying, 0 selling).
Estimated Holder Cost Basis
Quarter ended Jun 30, 2026, on that quarter's share basisEstimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.
Estimated cost covers 93.3% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.
Shared Holders
Companies PLRX's active holders also own, quarter ended Jun 30, 2026| # | Company | Shared holders |
|---|---|---|
| 1 | INGN Inogen Inc | 4 |
| 2 | FULC Fulcrum Therapeutics, Inc. | 6 |
| 3 | NKTX Nkarta, Inc. | 5 |
| 4 | JANX Janux Therapeutics, Inc. | 5 |
| 5 | LKFT Lakefront Biotherapeutics NV | 4 |
| 6 | SEER Seer, Inc. | 4 |
| 7 | MXCT Maxcyte, Inc. | 5 |
| 8 | BCYC Bicycle Therapeutics PLC | 5 |
| 9 | EPRX Eupraxia Pharmaceuticals Inc. | 5 |
| 10 | ALEC Alector, Inc. | 5 |
Shareholder Targets
13F filers that own its peers but not PLRX, quarter ended Jun 30, 2026Found through its holder-overlap peers: INGN, FULC, NKTX, JANX, LKFT, SEER, MXCT, BCYC, EPRX, ALEC, PMVP, PRQR, BOLD, ARQ, ENGN, IKT, ACET, LXEO, CRBP, ABOS. 471 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | GILEAD SCIENCES, INC. Unknown, Concentrated | $500,890,160 1 held | LKFT |
| 2 | RA CAPITAL MANAGEMENT, L.P. Registered adviser, Concentrated | $289,835,496 5 held | JANX, ABOS, NKTX |
| 3 | Madison Avenue Partners, LP Registered adviser, Concentrated | $103,365,253 1 held | LKFT |
| 4 | EcoR1 Capital, LLC Registered adviser, Concentrated | $73,952,736 2 held | LKFT, FULC |
| 5 | Affinity Asset Advisors, LLC Registered adviser, Diversified active | $52,950,749 6 held | LXEO, EPRX, PRQR |
| 6 | Nantahala Capital Management, LLC Registered adviser, Diversified active | $52,694,605 5 held | FULC, JANX, ALEC |
| 7 | ORBIMED ADVISORS LLC Registered adviser, Diversified active | $51,809,434 5 held | LXEO, CRBP, JANX |
| 8 | TCG Crossover Management, LLC Unknown, Diversified active | $47,588,517 2 held | JANX, ALEC |
| 9 | BAKER BROS. ADVISORS LP Registered adviser, Concentrated | $46,153,913 1 held | BCYC |
| 10 | SUVRETTA CAPITAL MANAGEMENT, LLC Registered adviser, Diversified active | $43,190,621 2 held | LXEO, FULC |
Fund Ownership of PLRX by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 5.23% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 0.65% | 401,306 |
| Index ETFs | 4.58% | 2,837,194 |
| Active ETFs | 0.00% | 0 |
| Active funds | 1.27% | 789,116 |
| Unclassified | 0.09% | 55,129 |
| All registered funds | 6.59% | 4,082,745 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Mid TANG CAPITAL MANAGEMENT LLC | $7,001,037 | 12.77% | 6,141,261 | Shares | 2026-08-14 | |
| Mid ADAR1 Capital Management, LLC Registered adviser | $6,281,085 | 11.46% | 5,509,724 | Shares | 2026-08-14 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $2,782,000 | 5.08% | 2,440,351 | Shares | 2026-08-13 | |
| Large ACADIAN ASSET MANAGEMENT LLC | $2,754,819 | 5.03% | 2,416,508 | Shares | 2026-08-13 | |
| Mega TWO SIGMA INVESTMENTS, LP Registered adviser | $2,579,628 | 4.71% | 2,262,832 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $2,442,137 | 4.46% | 2,142,226 | Shares | 2026-09-02 | |
| Large RENAISSANCE TECHNOLOGIES LLC Registered adviser | $2,336,856 | 4.26% | 2,049,874 | Shares | 2026-08-13 | |
| Mid Monaco Asset Management SAM | $2,210,171 | 4.03% | 1,938,747 | Shares | 2026-08-07 | |
| Small Lynx1 Capital Management LP Registered adviser | $2,049,799 | 3.74% | 1,798,070 | Shares | 2026-08-13 | |
| Small BML Capital Management, LLC Exempt adviser | $1,762,596 | 3.22% | 1,546,137 | Shares | 2026-08-07 | |
| Small Prosight Management, LP | $1,562,065 | 2.85% | 1,370,233 | Shares | 2026-08-14 | |
| Small Peapod Lane Capital LLC Registered adviser | $1,492,274 | 2.72% | 1,309,013 | Shares | 2026-07-27 | |
| Large Woodline Partners LP Registered adviser | $1,478,048 | 2.70% | 1,296,534 | Shares | 2026-08-14 | |
| Mega BlackRock, Inc. Holding company | $1,312,381 | 2.39% | 1,151,214 | Shares | 2026-08-07 | |
| Small Ikarian Capital, LLC Registered adviser | $1,140,000 | 2.08% | 1,000,000 | Shares | 2026-08-14 | |
| Mid Eversept Partners, LP Registered adviser | $1,016,224 | 1.85% | 891,425 | Shares | 2026-08-14 | |
| Large MARSHALL WACE, LLP Exempt adviser | $952,041 | 1.74% | 835,124 | Shares | 2026-08-13 | |
| Mid Redmile Group, LLC Registered adviser | $880,223 | 1.61% | 772,126 | Shares | 2026-08-14 | |
| Mega JPMORGAN CHASE & CO Bank | $777,076 | 1.42% | 681,647 | Shares | 2026-08-12 | |
| Large JACOBS LEVY EQUITY MANAGEMENT, INC Registered adviser | $733,156 | 1.34% | 643,120 | Shares | 2026-08-14 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC Registered adviser | $659,577 | 1.20% | 578,577 | Shares | 2026-08-12 | |
| Mega UBS Group AG Bank | $651,806 | 1.19% | 571,760 | Shares | 2026-08-13 | |
| Mega MILLENNIUM MANAGEMENT LLC Registered adviser | $637,769 | 1.16% | 559,447 | Shares | 2026-08-14 | |
| Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC Registered adviser | $631,138 | 1.15% | 553,630 | Shares | 2026-08-14 | |
| Large Connor, Clark & Lunn Investment Management Ltd. Registered adviser | $611,132 | 1.11% | 536,081 | Shares | 2026-08-13 | |
| Large BESSEMER GROUP INC | $606,569 | 1.11% | 532,079 | Shares | 2026-08-12 | |
| Small DAFNA Capital Management LLC Registered adviser | $555,180 | 1.01% | 487,000 | Shares | 2026-08-14 | |
| Mid XTX Topco Ltd | $502,562 | 0.92% | 440,844 | Shares | 2026-08-14 | |
| Mid Laurion Capital Management LP Registered adviser | $470,587 | 0.86% | 412,796 | Shares | 2026-08-13 | |
| Mid TORNO CAPITAL, LLC | $400,647 | 0.73% | 351,445 | Shares | 2026-08-14 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $389,596 | 0.71% | 341,751 | Shares | 2026-08-13 | |
| Mid BOOTHBAY FUND MANAGEMENT, LLC Registered adviser | $345,420 | 0.63% | 303,000 | Shares | 2026-08-14 | |
| Mega MORGAN STANLEY Holding company | $340,831 | 0.62% | 298,976 | Shares | 2026-08-13 | |
| Mega SEI INVESTMENTS CO | $338,911 | 0.62% | 297,291 | Shares | 2026-08-14 | |
| Small Verdad Advisers, LP | $320,731 | 0.59% | 281,343 | Shares | 2026-08-14 | |
| Mid ArrowMark Colorado Holdings LLC Registered adviser | $320,555 | 0.58% | 281,189 | Shares | 2026-08-13 | |
| Small NANO CAP NEW MILLENNIUM GROWTH FUND L P | $313,500 | 0.57% | 275,000 | Shares | 2026-08-14 | |
| Mega STATE STREET CORP Bank | $288,896 | 0.53% | 253,418 | Shares | 2026-09-22 | |
| Small Stonepine Capital Management, LLC Registered adviser | $262,813 | 0.48% | 230,538 | Shares | 2026-08-17 | |
| Small Rangeley Capital, LLC Registered adviser | $256,500 | 0.47% | 225,000 | Shares | 2026-08-14 | |
| Mega GOLDMAN SACHS GROUP INC Holding company | $237,786 | 0.43% | 208,585 | Shares | 2026-08-14 | |
| Small HighMark Wealth Management LLC Registered adviser | $189,495 | 0.35% | 166,224 | Shares | 2026-08-12 | |
| Mid GSA CAPITAL PARTNERS LLP Registered adviser | $184,914 | 0.34% | 162,206 | Shares | 2026-08-06 | |
| Mega VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser | $175,231 | 0.32% | 153,712 | Shares | 2026-08-13 | |
| Mega JANE STREET GROUP, LLC | $148,144 | 0.27% | 129,951 | Shares | 2026-08-14 | |
| Mega NORTHERN TRUST CORP Bank | $142,568 | 0.26% | 125,060 | Shares | 2026-08-13 | |
| Mid ALGERT GLOBAL LLC Registered adviser | $140,678 | 0.26% | 123,402 | Shares | 2026-08-13 | |
| Large OSAIC HOLDINGS, INC. Holding company | $131,013 | 0.24% | 114,924 | Shares | 2026-08-14 | |
| Mega Invesco Ltd. Adviser | $119,332 | 0.22% | 104,678 | Shares | 2026-08-14 | |
| Small Bond & Devick Financial Network, Inc. Registered adviser | $114,182 | 0.21% | 100,160 | Shares | 2026-07-16 | |
| Mega DIMENSIONAL FUND ADVISORS LP Registered adviser | $113,740 | 0.21% | 99,773 | Shares | 2026-08-11 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $93,366 | 0.17% | 81,900 | Put | 2026-08-14 | |
| Mega JANE STREET GROUP, LLC | $70,566 | 0.13% | 61,900 | Call | 2026-08-14 | |
| Mega AMERIPRISE FINANCIAL INC Adviser | $62,847 | 0.11% | 55,129 | Shares | 2026-08-14 | |
| Large Squarepoint Ops LLC Registered adviser | $46,527 | 0.08% | 40,814 | Shares | 2026-08-14 | |
| Small Headlands Technologies LLC | $38,404 | 0.07% | 33,688 | Shares | 2026-08-13 | |
| Large Quadrature Capital Ltd | $37,939 | 0.07% | 33,280 | Shares | 2026-08-07 | |
| Large TUDOR INVESTMENT CORP ET AL Registered adviser | $33,891 | 0.06% | 29,729 | Shares | 2026-08-14 | |
| Large FEDERATED HERMES, INC. Adviser | $33,122 | 0.06% | 29,055 | Shares | 2026-08-12 | |
| Large PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO Benefit plan | $32,490 | 0.06% | 28,500 | Shares | 2026-08-17 | |
| Micro Spark Investment Management LLC Registered adviser | $25,764 | 0.05% | 22,600 | Shares | 2026-08-10 | |
| Large Blackstone Inc. Adviser | $25,314 | 0.05% | 22,206 | Shares | 2026-08-14 | |
| Large Point72 Asset Management, L.P. Registered adviser | $22,883 | 0.04% | 20,073 | Shares | 2026-08-14 | |
| Mega Vanguard Global Advisers, LLC Registered adviser | $22,237 | 0.04% | 19,507 | Shares | 2026-08-13 | |
| Large Universal- Beteiligungs- und Servicegesellschaft mbH | $20,594 | 0.04% | 18,065 | Shares | 2026-08-06 | |
| Mega Bank of New York Mellon Corp Bank | $18,275 | 0.03% | 16,032 | Shares | 2026-08-06 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $17,647 | 0.03% | 15,480 | Shares | 2026-08-14 | |
| Large NewEdge Advisors, LLC Registered adviser | $17,100 | 0.03% | 15,000 | Shares | 2026-08-12 | |
| Mega JANE STREET GROUP, LLC | $13,794 | 0.03% | 12,100 | Put | 2026-08-14 | |
| Mid Fiduciary Trust Co | $13,246 | 0.02% | 11,620 | Shares | 2026-08-13 | |
| Mega Qube Research & Technologies Ltd Exempt adviser | $11,437 | 0.02% | 10,033 | Shares | 2026-08-14 | |
| Mid SIMPLEX TRADING, LLC | $5,614 | 0.01% | 4,925 | Shares | 2026-08-12 | |
| Mega ROYAL BANK OF CANADA Bank | $1,133 | 0.00% | 995 | Shares | 2026-08-14 | |
| Large Rockefeller Capital Management L.P. Registered adviser | $752 | 0.00% | 660 | Shares | 2026-08-13 | |
| Mega BNP PARIBAS ARBITRAGE, SA Non-US | $748 | 0.00% | 657 | Shares | 2026-08-13 | |
| Mid HARBOUR INVESTMENTS, INC. Registered adviser | $672 | 0.00% | 590 | Shares | 2026-08-12 | |
| Mega BARCLAYS PLC Bank | $485 | 0.00% | 426 | Shares | 2026-08-14 | |
| Mega FMR LLC Holding company | $477 | 0.00% | 419 | Shares | 2026-08-13 | |
| Mid SBI Securities Co., Ltd. Non-US | $342 | 0.00% | 300 | Shares | 2026-07-23 | |
| Small Truvestments Capital LLC | $57 | 0.00% | 50 | Shares | 2026-08-12 | |
| Mega WELLS FARGO & COMPANY/MN Bank | $57 | 0.00% | 50 | Shares | 2026-08-14 | |
| Large Zurcher Kantonalbank (Zurich Cantonalbank) Non-US | $41 | 0.00% | 36 | Shares | 2026-08-12 | |
| Small Capital Advisors, Ltd. LLC Registered adviser | $35 | 0.00% | 31 | Shares | 2026-07-16 | |
| Small Caitong International Asset Management Co., Ltd | $9 | 0.00% | 8 | Shares | 2026-08-05 | |
| Large Farther Finance Advisors, LLC Registered adviser | $5 | 0.00% | 5 | Shares | 2026-10-08 | |
| Large FIFTH THIRD BANCORP Bank | $4 | 0.00% | 4 | Shares | 2026-08-05 | |
| Mid IFG Advisory, LLC Registered adviser | $4 | 0.00% | 4 | Shares | 2026-08-14 | |
| Mid Global Retirement Partners, LLC | $4 | 0.00% | 4 | Shares | 2026-08-06 |