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PLRX

Pliant Therapeutics, Inc.

Company with tickers: PLRX

CIK
1746473
CUSIP
729139105
Shares Outstanding
61,920,249
13F Activity (30d)
85 filings 85 filers
Holders: 91
Total Value: $62,829,696
Total Shares: 49,864,878

Institutional Ownership Trend

24 quarters

Holder Concentration

Across 91 13F filers · Δ vs Dec 31, 2025
Top Holder
12.3%
Jun 2023 → Mar 2026 · range 7.5% – 13.1%
−0.8 pts
Top 5
34.8%
Jun 2023 → Mar 2026 · range 32.6% – 42.7%
−1.5 pts
Top 10
55.0%
Jun 2023 → Mar 2026 · range 53.8% – 65.2%
+0.1 pts
HHI
435
Jun 2023 → Mar 2026 · range 384 – 541
Broadly held −12

Quarterly Activity

vs Dec 31, 2025
New
15
Increased
24
Decreased
27
Sold Out
20
Unchanged
25
Holder count: -5
Institutional value: +10.1%
Shares held: +6.6%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mid ADAR1 Capital Management, LLC +2,511,307 2,585,126
Mega TWO SIGMA INVESTMENTS, LP +1,299,845 2,253,138
Large RENAISSANCE TECHNOLOGIES LLC +807,024 1,852,842
Mega MILLENNIUM MANAGEMENT LLC +771,687 1,180,518
Mega CITADEL ADVISORS LLC +554,667 3,263,399

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid Redmile Group, LLC −844,102 772,126
Large Centiva Capital, LP −567,475 432,525
Large Woodline Partners LP −359,361 1,666,830
Mega BANK OF AMERICA CORP /DE/ −359,069 352,708
Mega JPMORGAN CHASE & CO −351,052 861,823

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 2,343,101 $2,952,307
Small DAFNA Capital Management LLC 487,000 $613,620
Mid Laurion Capital Management LP 412,796 $520,122
Mega VANGUARD FIDUCIARY TRUST CO 339,540 $427,820
Mega VANGUARD PORTFOLIO MANAGEMENT LLC 153,810 $193,800

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 2,818,241 $3,438,252
Large TWO SIGMA ADVISERS, LP 1,245,600 $1,519,632
Small Seven Fleet Capital Management LP 276,500 $337,330
Mid RICE HALL JAMES & ASSOCIATES, LLC 147,705 $180,200
Small DIADEMA PARTNERS LP 144,914 $176,795
Filter: New 15 Increased 24 Reduced 27 Sold out 20 Unchanged 25
Showing 95 of 95
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mid TANG CAPITAL MANAGEMENT LLC $7,740,346 12.32% 6,143,132
Mega CITADEL ADVISORS LLC $4,065,514 6.47% 3,226,599
Small Blue Owl Capital Holdings LP $3,741,190 5.95% 2,969,199
Mid ADAR1 Capital Management, LLC $3,257,258 5.18% 2,585,126
Large ACADIAN ASSET MANAGEMENT LLC $3,044,800 4.85% 2,416,508
Mega VANGUARD CAPITAL MANAGEMENT LLC $2,952,307 4.70% 2,343,101
Mega TWO SIGMA INVESTMENTS, LP $2,838,953 4.52% 2,253,138
Small Monaco Asset Management SAM $2,442,821 3.89% 1,938,747
Large RENAISSANCE TECHNOLOGIES LLC $2,334,580 3.72% 1,852,842
Small Prosight Management, LP $2,101,176 3.34% 1,667,600
Large Woodline Partners LP $2,100,205 3.34% 1,666,830
Small BML Capital Management, LLC $1,948,132 3.10% 1,546,137
Small Peapod Lane Capital LLC $1,623,608 2.58% 1,288,578
Mega MILLENNIUM MANAGEMENT LLC $1,487,452 2.37% 1,180,518
Mega BlackRock, Inc. $1,381,500 2.20% 1,096,430
Mega UBS Group AG $1,333,022 2.12% 1,057,954
Large MARSHALL WACE, LLP $1,254,925 2.00% 995,973
Mid Eversept Partners, LP $1,123,195 1.79% 891,425
Mega JPMORGAN CHASE & CO $1,085,896 1.73% 861,823
Mid Redmile Group, LLC $972,878 1.55% 772,126
Large JACOBS LEVY EQUITY MANAGEMENT, INC $905,364 1.44% 718,543
Mega GOLDMAN SACHS GROUP INC $752,014 1.20% 596,837
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $697,573 1.11% 553,630
Large BESSEMER GROUP INC $670,419 1.07% 532,079
Large Connor, Clark & Lunn Investment Management Ltd. $651,990 1.04% 517,453
Mega MORGAN STANLEY $637,229 1.01% 505,739
Mid XTX Topco Ltd $631,055 1.00% 500,838
Small DAFNA Capital Management LLC $613,620 0.98% 487,000
Large Centiva Capital, LP $544,981 0.87% 432,525
Mega GEODE CAPITAL MANAGEMENT, LLC $525,765 0.84% 417,274
Mid Laurion Capital Management LP $520,122 0.83% 412,796
Mid GSA CAPITAL PARTNERS LLP $506,635 0.81% 402,092
Mega JANE STREET GROUP, LLC $449,559 0.72% 356,794
Mega BANK OF AMERICA CORP /DE/ Bank $444,412 0.71% 352,708
Small TORNO CAPITAL, LLC $441,000 0.70% 350,000
Mega VANGUARD FIDUCIARY TRUST CO Bank $427,820 0.68% 339,540
Large SEI INVESTMENTS CO $374,585 0.60% 297,291
Mid ArrowMark Colorado Holdings LLC $354,298 0.56% 281,189
Micro NANO CAP NEW MILLENNIUM GROWTH FUND L P $346,500 0.55% 275,000
Mega STATE STREET CORP $319,306 0.51% 253,418
Small Rangeley Capital, LLC $283,500 0.45% 225,000
Small Stonepine Capital Management, LLC $283,059 0.45% 224,650
Micro HighMark Wealth Management LLC $209,442 0.33% 166,224
Large Squarepoint Ops LLC $205,650 0.33% 163,215
Mega NORTHERN TRUST CORP Bank $194,260 0.31% 154,176
Mega VANGUARD PORTFOLIO MANAGEMENT LLC $193,800 0.31% 153,810
Mega Invesco Ltd. $145,174 0.23% 115,218
Large OSAIC HOLDINGS, INC. $144,804 0.23% 114,924
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $140,490 0.22% 111,500
Mid Hennion & Walsh Asset Management, Inc. $134,448 0.21% 106,705
Micro Bond & Devick Financial Network, Inc. $126,201 0.20% 100,160
Mega DIMENSIONAL FUND ADVISORS LP $125,712 0.20% 99,773
Micro Verdad Advisers, LP $123,883 0.20% 98,320
Mid ALGERT GLOBAL LLC $106,409 0.17% 84,452
Large FEDERATED HERMES, INC. $78,940 0.13% 62,651
Mega AMERIPRISE FINANCIAL INC $69,462 0.11% 55,129
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $66,724 0.11% 52,956
Mid Quadrature Capital Ltd $64,236 0.10% 50,981
Mid SIMPLEX TRADING, LLC $60,548 0.10% 48,054
Large Point72 Asset Management, L.P. $59,288 0.09% 47,054
Mega CITADEL ADVISORS LLC $46,368 0.07% 36,800
Large TUDOR INVESTMENT CORP ET AL $37,458 0.06% 29,729
Large PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO Pension $35,910 0.06% 28,500
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $28,602 0.05% 22,700
Large Blackstone Inc. $27,979 0.04% 22,206
Mega Vanguard Global Advisers, LLC $24,578 0.04% 19,507
Small Bronte Capital Management Pty Ltd. $23,452 0.04% 18,613
Large Universal- Beteiligungs- und Servicegesellschaft mbH $22,761 0.04% 18,065
Mega Bank of New York Mellon Corp Bank $19,937 0.03% 15,824
Large SG Americas Securities, LLC Broker-Dealer $15,881 0.03% 12,604
Mega JANE STREET GROUP, LLC $15,750 0.03% 12,500
Mid Fiduciary Trust Co Bank $14,641 0.02% 11,620
Large HRT FINANCIAL LP $14,106 0.02% 11,196
Large Qube Research & Technologies Ltd $13,817 0.02% 10,966
Mid Vanguard Personalized Indexing Management, LLC $12,636 0.02% 10,029
Mid Tower Research Capital LLC (TRC) $4,176 0.01% 3,315
Mega RHUMBLINE ADVISERS $2,997 0.00% 2,379
Micro Owl Creek Wealth Partners LLC $2,898 0.00% 2,300
Mega ROYAL BANK OF CANADA Bank $1,254 0.00% 997
Large Rockefeller Capital Management L.P. $831 0.00% 660
Mega BNP PARIBAS ARBITRAGE, SA $827 0.00% 657
Mega FMR LLC $659 0.00% 524
Mid HARBOUR INVESTMENTS, INC. $614 0.00% 488
Mid MAI Capital Management $504 0.00% 400
Mid SBI Securities Co., Ltd. Broker-Dealer $378 0.00% 300
Large CWM, LLC $267 0.00% 212
Large NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $126 0.00% 100
Small Truvestments Capital LLC $63 0.00% 50
Mega WELLS FARGO & COMPANY/MN $63 0.00% 50
Large Zurcher Kantonalbank (Zurich Cantonalbank) Bank $45 0.00% 36
Mega BARCLAYS PLC $42 0.00% 34
Small Capital Advisors, Ltd. LLC $25 0.00% 20
Mid Farther Finance Advisors, LLC $6 0.00% 5
Large FIFTH THIRD BANCORP Bank $5 0.00% 4
Small Caitong International Asset Management Co., Ltd $5 0.00% 4

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