PRQR · ProQR Therapeutics N.V.

$2.07 -0.02 (-0.96%) At close · Sep 4

Market Cap

$292.12M

141.12M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Quarter:

Holders: 69

Total Value: $112,695,134

Total Shares: 60,588,799

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 69 13F filers · Δ vs Mar 31, 2026

Top Holder

14.9%

−2.9 pts

Top 5

53.5%

−1.9 pts

Top 10

71.9%

−3.9 pts

HHI

755

Broadly held−92

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: 0

Institutional value: +98.2%

Shares held: +72.6%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large Aberdeen Group plc	+5,615,542	8,932,507
Mid Affinity Asset Advisors, LLC	+3,089,658	5,543,936
Large ADAGE CAPITAL PARTNERS GP, L.L.C.	+2,762,430	9,015,897
Small Ikarian Capital, LLC	+1,933,701	3,425,930
Small DIADEMA PARTNERS LP	+745,933	926,016

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large Point72 Asset Management, L.P.	−705,190	50,652
Mid Monaco Asset Management SAM	−174,316	244,487
Mega BANK OF AMERICA CORP /DE/	−127,070	58,040
Small PLATINUM INVESTMENT MANAGEMENT LTD	−76,086	1,159,428
Small DAFNA Capital Management LLC	−37,200	1,530,361

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Large Woodline Partners LP	3,277,143	$6,095,485
Small HEIGHTS CAPITAL MANAGEMENT, INC	2,762,430	$5,138,119
Small SPHERA FUNDS MANAGEMENT LTD.	1,757,458	$3,268,871
Small Squadron Capital Management LLC	1,511,496	$2,811,382
Mid 683 Capital Management, LLC	1,393,067	$2,591,104

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Small Sio Capital Management, LLC	1,954,715	$3,166,638
Large Walleye Capital LLC	607,529	$984,196
Mega NORTHERN TRUST CORP	291,314	$471,928
Small FRANKLIN STREET ADVISORS INC /NC	150,000	$243,000
Large MARSHALL WACE, LLP	115,945	$187,830

Filter: New 12 Increased 25 Reduced 11 Sold out 12 Unchanged 21

Showing 69 of 69

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

ADAGE CAPITAL PARTNERS GP, L.L.C.

$16,769,568

14.88%

9,015,897

Aberdeen Group plc

$16,614,463

14.74%

8,932,507

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	8,932,507	$16,614,463	100.0%	Defined

Affinity Asset Advisors, LLC

$10,311,720

9.15%

5,543,936

Privium Fund Management B.V.

$10,267,244

9.11%

5,520,024

Ikarian Capital, LLC

$6,372,229

5.65%

3,425,930

Woodline Partners LP

$6,095,485

5.41%

3,277,143

HEIGHTS CAPITAL MANAGEMENT, INC

$5,138,119

4.56%

2,762,430

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CVI Investments, Inc.	2,762,430	$5,138,119	100.0%	Other

MORGAN STANLEY

$3,287,019

2.92%

1,767,215

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO. LLC	33,019	$61,415	1.9%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	1,703,996	$3,169,432	96.4%	Defined
MORGAN STANLEY SMITH BARNEY LLC	30,200	$56,172	1.7%	Defined

SPHERA FUNDS MANAGEMENT LTD.

$3,268,871

2.90%

1,757,458

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	1,757,458	$3,268,871	100.0%	Defined

Kynam Capital Management, LP

$2,913,349

2.59%

1,566,317

DAFNA Capital Management LLC

$2,846,471

2.53%

1,530,361

Squadron Capital Management LLC

$2,811,382

2.49%

1,511,496

683 Capital Management, LLC

$2,591,104

2.30%

1,393,067

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
683 Capital Partners, LP	1,393,067	$2,591,104	100.0%	Defined

CITADEL ADVISORS LLC

$2,202,823

1.95%

1,184,314

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	34,943	$64,993	3.0%	Defined
Held directly	1,149,371	$2,137,830	97.0%	Defined

PLATINUM INVESTMENT MANAGEMENT LTD

$2,156,536

1.91%

1,159,428

TWO SIGMA INVESTMENTS, LP

$2,118,009

1.88%

1,138,715

Eversept Partners, LP

$1,901,412

1.69%

1,022,265

BOOTHBAY FUND MANAGEMENT, LLC

$1,764,648

1.57%

948,736

DIADEMA PARTNERS LP

$1,722,389

1.53%

926,016

UBS Group AG

$1,188,991

1.06%

639,243

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	639,243	$1,188,991	100.0%	Defined

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$1,153,200

1.02%

620,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	620,000	$1,153,200	100.0%	Defined

M28 Capital Management LP

$1,115,614

0.99%

599,793

RAYMOND JAMES FINANCIAL INC

$1,062,194

0.94%

571,073

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	190,887	$355,049	33.4%	Defined
Raymond James Financial Services Advisors, Inc.	380,186	$707,145	66.6%	Defined

Lynx1 Capital Management LP

$969,828

0.86%

521,413

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Lynx1 Capital Advisors LLC	521,413	$969,828	100.0%	Other

JANE STREET GROUP, LLC

$846,493

0.75%

455,104

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	295,290	$549,239	64.9%	Defined
Jane Street Global Trading, LLC	159,814	$297,254	35.1%	Defined

STEMPOINT CAPITAL LP

$801,760

0.71%

431,054

BNP PARIBAS ARBITRAGE, SA

$512,673

0.45%

275,631

Monaco Asset Management SAM

$454,745

0.40%

244,487

Persistent Asset Partners Ltd

$439,804

0.39%

236,454

Palo Alto Investors LP

$351,181

0.31%

188,807

Burkehill Global Management, LP

$327,811

0.29%

176,243

GSA CAPITAL PARTNERS LLP

$323,349

0.29%

173,844

MILLENNIUM MANAGEMENT LLC

$299,467

0.27%

161,004

DEUTSCHE BANK AG\

$202,297

0.18%

108,762

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS Investments UK Ltd	108,762	$202,297	100.0%	Defined

OneDigital Investment Advisors LLC

$158,100

0.14%

85,000

Quadrature Capital Ltd

$157,739

0.14%

84,806

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	84,806	$157,739	100.0%	Other

RFG Advisory, LLC

$119,040

0.11%

64,000

BANK OF AMERICA CORP /DE/

$107,954

0.10%

58,040

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	58,040	$107,954	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$107,874

0.10%

57,997

Point72 Asset Management, L.P.

$94,212

0.08%

50,652

Keating Financial Advisory Services, Inc.

$88,446

0.08%

47,552

Velan Capital Investment Management LP

$83,700

0.07%

45,000

GUGGENHEIM CAPITAL LLC

$74,314

0.07%

39,954

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GUGGENHEIM FUNDS DISTRIBUTORS, LLC	39,954	$74,314	100.0%	Defined

Steward Partners Investment Advisory, LLC

$65,548

0.06%

35,241

Axiom Investment Management LLC

$57,660

0.05%

31,000

MOODY LYNN LIEBERSON & WALKER, LLC

$46,500

0.04%

25,000

Vanguard Personalized Indexing Management, LLC

$41,096

0.04%

22,095

Mariner, LLC

$37,514

0.03%

20,169

Verdad Advisers, LP

$35,526

0.03%

19,100

NANO CAP NEW MILLENNIUM GROWTH FUND L P

$32,550

0.03%

17,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AZG TANGIBLE ASSETS FUND LLC	17,500	$32,550	100.0%	Sole

TWO SIGMA SECURITIES, LLC

$29,789

0.03%

16,016

Atom Investors LP

$24,379

0.02%

13,107

China Universal Asset Management Co., Ltd.

$23,250

0.02%

12,500

Virtu Financial LLC

$21,624

0.02%

11,626

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Virtu Americas LLC	11,626	$21,624	100.0%	Defined

WETZEL INVESTMENT ADVISORS, INC.

$19,530

0.02%

10,500

TRUIST FINANCIAL CORP

$18,600

0.02%

10,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Truist Advisory Services, Inc.	10,000	$18,600	100.0%	Defined

ADAR1 Capital Management, LLC

$18,600

0.02%

10,000

WELLS FARGO & COMPANY/MN

$7,440

0.01%

4,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	4,000	$7,440	100.0%	Defined

BlackRock, Inc.

$7,337

0.01%

3,945

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	3,945	$7,337	100.0%	Sole

ROYAL BANK OF CANADA

$6,147

0.01%

3,305

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Capital Markets, LLC	3,000	$5,580	90.8%	Defined
RBC Dominion Securities Inc.	200	$372	6.1%	Defined
Held directly	105	$195	3.2%	Sole

Hilton Head Capital Partners, LLC

$2,611

0.00%

1,404

PFS Partners, LLC

$1,860

0.00%

1,000

Farther Finance Advisors, LLC

$1,860

0.00%

1,000

SBI Securities Co., Ltd.

$957

0.00%

515

JPMORGAN CHASE & CO

$526

0.00%

283

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Securities plc	283	$526	100.0%	Defined

SIMPLEX TRADING, LLC

$504

0.00%

271

TD Waterhouse Canada Inc.

$74

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TORONTO DOMINION BANK	40	$74	100.0%	Defined

Medallion Wealth Advisors, LLC

$18

0.00%

Caitong International Asset Management Co., Ltd

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	13,759	$22,289	4.7%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	277,555	$449,639	95.3%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	115,945	$187,830	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	77,287	$125,204	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Capital Management LLC	44,592	$72,239	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	31,518	$51,059	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	13,700	$22,194	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	12,206	$19,773	100.0%	Other

Key facts CIK 1612940 CUSIP N71542109 13F (30d) 48 filings 48 filers Visit website Investor relations