Position in PLRX
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$2,838,953
+$1,675,936 QoQ
Shares Held
2,253,138
+136.4% QoQ
Ownership
3.64%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2021
17 quarters on record
Voting authority
Sole 98.13593308532367.ToString("F0")%
Shared 0.ToString("F0")%
None 1.8640669146763316.ToString("F0")%
Common Shares in PLRX Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. PLRX ranks #138 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in PLRX
Export CSV
17 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $2,838,953 | 2,253,138 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $1,163,017 | 953,293 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $1,159,217 | 783,255 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $322,663 | 278,158 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $371,637 | 275,287 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $1,278,517 | 97,078 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $1,514,717 | 135,122 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $2,639,899 | 245,572 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $1,594,657 | 107,024 | Shares | Sole | 2024-05-15 | |
| 2023-09-30 | $1,780,974 | 102,709 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $5,785,462 | 319,286 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $11,082,890 | 416,650 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $4,203,211 | 217,445 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $5,180,866 | 248,007 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $112,140 | 14,000 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $878,198 | 125,278 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $1,565,581 | 115,969 | Shares | Sole | 2022-02-14 | |
| No filing history on record for this holder in this stock. | ||||||