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BCYC · Bicycle Therapeutics PLC · Holdings

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$3.86 +0.03 (+0.78%) At close · Sep 11
Rebalance outlook locked
Market Cap
$270.17M
Shares
69.99M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →
Holders: 103
Total Value: $159,934,267
Total Shares: 37,720,357
Showing 1–100 of 111 holdings by value · page 1 of 2

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 103 13F filers · Δ vs Mar 31, 2026
Top Holder
28.9%
Sep 2023 → Jun 2026 · range 11.2% – 29.5%
+0.1 pts
Top 5
61.1%
Sep 2023 → Jun 2026 · range 39.3% – 61.1%
+0.2 pts
Top 10
75.7%
Sep 2023 → Jun 2026 · range 58.2% – 77.7%
−1.7 pts
HHI
1,173
Sep 2023 → Jun 2026 · range 490 – 1,201
Broadly held+2

Quarterly Activity

vs Mar 31, 2026
New
18
Increased
35
Decreased
17
Sold Out
13
Unchanged
33
Holder count: +5
Institutional value: -8.9%
Shares held: -0.3%

Top Buyers

vs Mar 31, 2026
Institution Added Now Holds Open
RENAISSANCE TECHNOLOGIES LLC +554,100 1,533,400
Qube Research & Technologies Ltd +466,950 775,567
MARSHALL WACE, LLP +420,605 797,940
Peapod Lane Capital LLC +416,872 537,978
MILLENNIUM MANAGEMENT LLC +269,981 553,967

Top Sellers

vs Mar 31, 2026
Institution Sold Now Holds Open
Birchview Capital, LP −149,983 313,616
PRICE T ROWE ASSOCIATES INC /MD/ −126,093 902,150
AXQ CAPITAL, LP −35,766 27,368
ADAR1 Capital Management, LLC −20,660 50,638
UBS Group AG −16,700 15,459

Top New Positions

vs Mar 31, 2026
Institution Acquired Value (USD) Open
Sculptor Capital LP 197,904 $839,112
Quadrature Capital Ltd 104,092 $441,350
NANO CAP NEW MILLENNIUM GROWTH FUND L P 80,000 $339,200
Marquette Asset Management, LLC 72,854 $308,900
Verdad Advisers, LP 51,100 $216,664

Top Sold-Out Positions

vs Mar 31, 2026
Institution Previously Held Last Value (USD) Open
Siren, L.L.C. 1,560,882 $7,242,492
PRINCIPAL FINANCIAL GROUP INC 1,174,625 $5,450,260
SILVERCREST ASSET MANAGEMENT GROUP LLC 428,684 $1,989,093
PLATINUM INVESTMENT MANAGEMENT LTD 184,603 $856,557
Marex Group plc 115,000 $533,600
Filter: New 18 Increased 35 Reduced 17 Sold out 13 Unchanged 33
Showing 100 of 111
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
BAKER BROS. ADVISORS LP $46,153,913 28.86% 10,885,357
FCPM III SERVICES B.V. $14,706,143 9.20% 3,468,430
ARMISTICE CAPITAL, LLC $14,407,520 9.01% 3,398,000
Long Focus Capital Management, LLC $14,037,312 8.78% 3,310,687
ACADIAN ASSET MANAGEMENT LLC $8,344,426 5.22% 1,968,025
RENAISSANCE TECHNOLOGIES LLC $6,501,616 4.07% 1,533,400
GSK plc $6,485,338 4.06% 1,529,561
PRICE T ROWE ASSOCIATES INC /MD/ $3,825,116 2.39% 902,150
MARSHALL WACE, LLP $3,383,265 2.12% 797,940
Qube Research & Technologies Ltd $3,288,404 2.06% 775,567
MORGAN STANLEY $2,829,219 1.77% 667,269
SCHRODER INVESTMENT MANAGEMENT GROUP $2,611,131 1.63% 615,833
CITADEL ADVISORS LLC $2,349,913 1.47% 554,225
MILLENNIUM MANAGEMENT LLC $2,348,820 1.47% 553,967
Peapod Lane Capital LLC $2,281,026 1.43% 537,978
DIADEMA PARTNERS LP $1,961,949 1.23% 462,724
TWO SIGMA INVESTMENTS, LP $1,842,606 1.15% 434,577
JANE STREET GROUP, LLC $1,662,770 1.04% 392,163
Birchview Capital, LP $1,329,731 0.83% 313,616
BlackRock, Inc. $1,188,836 0.74% 280,386
MOORE CAPITAL MANAGEMENT, LP $1,166,000 0.73% 275,000
Rangeley Capital, LLC $1,074,840 0.67% 253,500
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,042,616 0.65% 245,900
Palo Alto Investors LP $856,013 0.54% 201,890
Sculptor Capital LP $839,112 0.52% 197,904
Eversept Partners, LP $808,631 0.51% 190,715
PINNACLE ASSOCIATES LTD $805,557 0.50% 189,990
FLAX POND CAPITAL, LLC $763,564 0.48% 180,086
Jump Financial, LLC $708,504 0.44% 167,100
Point72 Asset Management, L.P. $635,728 0.40% 149,936
MANUFACTURERS LIFE INSURANCE COMPANY, THE $542,139 0.34% 127,863
GOLDMAN SACHS GROUP INC $514,231 0.32% 121,281
Persistent Asset Partners Ltd $497,156 0.31% 117,254
XTX Topco Ltd $465,556 0.29% 109,801
Quadrature Capital Ltd $441,350 0.28% 104,092
TD Asset Management Inc $390,046 0.24% 91,992
Virtus Investment Advisers, LLC $342,545 0.21% 80,789
NANO CAP NEW MILLENNIUM GROWTH FUND L P $339,200 0.21% 80,000
EntryPoint Capital, LLC $329,630 0.21% 77,743
SUSQUEHANNA INTERNATIONAL GROUP, LLP $315,880 0.20% 74,500
Marquette Asset Management, LLC $308,900 0.19% 72,854
HRT FINANCIAL LP $280,844 0.18% 66,237
DAFNA Capital Management LLC $273,446 0.17% 64,492
State of Tennessee, Department of Treasury $259,288 0.16% 61,153
CITADEL ADVISORS LLC $238,288 0.15% 56,200
SEI INVESTMENTS CO $223,804 0.14% 52,784
ALPS ADVISORS INC $216,757 0.14% 51,122
Verdad Advisers, LP $216,664 0.14% 51,100
ADAR1 Capital Management, LLC $214,705 0.13% 50,638
JANE STREET GROUP, LLC $151,792 0.09% 35,800
SIMPLEX TRADING, LLC $149,383 0.09% 35,232
SUSQUEHANNA INTERNATIONAL GROUP, LLP $135,497 0.08% 31,957
Trexquant Investment LP $131,626 0.08% 31,044
STATE STREET CORP $130,714 0.08% 30,829
GSA CAPITAL PARTNERS LLP $130,528 0.08% 30,785
WOODSTOCK CORP $123,579 0.08% 29,146
AXQ CAPITAL, LP $116,040 0.07% 27,368
JANE STREET GROUP, LLC $113,632 0.07% 26,800
FNY Investment Advisers, LLC $111,300 0.07% 26,250
D. E. Shaw & Co., Inc. $107,937 0.07% 25,457
Invesco Ltd. $105,160 0.07% 24,802
National Philanthropic Trust $104,825 0.07% 24,723
Forefront Analytics, LLC $92,525 0.06% 21,822
STIFEL FINANCIAL CORP $86,830 0.05% 20,479
State of New Jersey Common Pension Fund D $85,245 0.05% 20,105
Vontobel Holding Ltd. $84,800 0.05% 20,000
Aigen Investment Management, LP $81,912 0.05% 19,319
GEODE CAPITAL MANAGEMENT, LLC $80,708 0.05% 19,035
CITADEL ADVISORS LLC $73,352 0.05% 17,300
RHUMBLINE ADVISERS $67,700 0.04% 15,967
UBS Group AG $65,546 0.04% 15,459
PORTLAND INVESTMENT COUNSEL INC. $63,600 0.04% 15,000
Federation des caisses Desjardins du Quebec $60,639 0.04% 14,302
Erste Asset Management GmbH $59,360 0.04% 14,000
Cerity Partners LLC $57,536 0.04% 13,570
Schonfeld Strategic Advisors LLC $56,811 0.04% 13,399
JPMORGAN CHASE & CO $55,356 0.03% 13,056
Walleye Capital LLC $55,120 0.03% 13,000
HORIZON KINETICS ASSET MANAGEMENT LLC $53,356 0.03% 12,584
Aquatic Capital Management LLC $52,334 0.03% 12,343
Jain Global LLC $50,880 0.03% 12,000
Crossmark Global Holdings, Inc. $48,344 0.03% 11,402
Pinnacle Wealth Management Advisory Group, LLC $46,576 0.03% 10,985
State of Wyoming $45,622 0.03% 10,760
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS $42,891 0.03% 10,116
GAMMA Investing LLC $32,664 0.02% 7,704
Walleye Capital LLC $32,648 0.02% 7,700
China Universal Asset Management Co., Ltd. $31,460 0.02% 7,420
NATIXIS $19,694 0.01% 4,645
Tower Research Capital LLC (TRC) $15,556 0.01% 3,669
BARCLAYS PLC $13,351 0.01% 3,149
ROYAL BANK OF CANADA $10,600 0.01% 2,500
Mirae Asset Global Investments Co., Ltd. $8,840 0.01% 2,085
GROUP ONE TRADING LLC $8,217 0.01% 1,938
ASSETMARK, INC $6,733 0.00% 1,588
CITIGROUP INC $4,982 0.00% 1,175
BNP PARIBAS ARBITRAGE, SA $4,307 0.00% 1,016
GF FUND MANAGEMENT CO. LTD. $4,078 0.00% 962
JONES FINANCIAL COMPANIES LLLP $2,968 0.00% 700
Quarry LP $2,276 0.00% 537
Key facts CIK 1761612 CUSIP 088786108 13F (30d) 4 filings 4 filers Visit website Investor relations