Avidity Partners Management LP

CIK

1791827

Location

DALLAS, TX

Portfolio Value

Small $584,570,627

Diversification

Diversified

Filing Date

Global Rank

#2,402 / 8,603 ▲ 689 · as of Mar 2026

Top Industry

Biotechnology 81.0%

3Y Alpha vs SPY

+7.0%

Period ended 3 months ago

Filed May 28, 2026 · 42d

25 quarters · since Mar 2020

Clone Performance

Jul 2023–Jul 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+86.7%

SPY

+76.5%

Annualised alpha

+2.3%

Max drawdown

−38.4%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

52 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

30.2%

+7.3 pts

Top 5

68.5%

+11.9 pts

Top 10

81.8%

+10.9 pts

HHI

1,408

Diversified+438

Portfolio Trend

25 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	99.4%	$581,052,027	49
Consumer Defensive	0.5%	$2,660,600	2
Consumer Cyclical	0.1%	$858,000	1

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

11 positions

Ticker	Company	Δ Shares	Shares	Value
CATX	Perspective Therapeutics, Inc.	+2,839,266	6,049,999	$25,228,495
IMUX	Immunic, Inc.	+2,000,000	6,699,411	$74,363,462
KPTI	Karyopharm Therapeutics Inc.	+329,175	463,741	$2,583,037
ELVN	Enliven Therapeutics, Inc.	+259,700	400,000	$15,680,000
ORKA	Oruka Therapeutics, Inc.	+100,000	760,424	$37,298,797
PVLA	Palvella Therapeutics, Inc.	+50,700	70,000	$8,725,500
PHAT	Phathom Pharmaceuticals, Inc.	+43,314	249,390	$2,770,722
TEVA	Teva Pharmaceutical Industries Ltd	+32,800	450,100	$13,557,012
RGEN	Repligen Corp	+27,500	77,800	$9,166,396
EHC	Encompass Health Corp	+10,400	42,000	$4,062,660
CORT	Corcept Therapeutics Inc	+8,000	30,000	$1,209,300
No positions match the current search.

Trimmed

Positions the filer reduced

10 positions

Ticker	Company	Δ Shares	Shares	Value
CNTX	Context Therapeutics Inc.	−506,588	4,998,267	$13,095,459
CGON	CG Oncology, Inc.	−183,751	1,288,948	$87,236,000
KVUE	Kenvue Inc.	−132,800	100,000	$1,724,000
ACAD	Acadia Pharmaceuticals Inc	−93,933	12,967	$288,645
BSX	Boston Scientific Corp	−54,500	60,000	$3,765,000
CNC	Centene Corp	−49,400	70,000	$2,291,800
GMAB	Genmab A/S	−42,000	50,000	$1,341,500
ICLR	Icon PLC	−17,100	16,000	$1,770,560
MDT	Medtronic plc	−7,600	100,000	$8,665,000
NTRA	Natera, Inc.	−2,800	9,000	$1,799,910
No positions match the current search.

New Positions

Positions the filer opened this quarter

25 positions

Ticker	Company	Shares	Value
VIR	Vir Biotechnology, Inc.	950,000	$8,512,000
AKTS	Aktis Oncology, Inc.	468,566	$8,382,645
DXCM	Dexcom Inc	90,000	$5,652,000
HUM	Humana Inc	25,000	$4,334,750
TENX	Tenax Therapeutics, Inc.	215,934	$3,452,784
GILD	Gilead Sciences, Inc.	20,000	$2,787,400
MSLE	Satellos Bioscience Inc.	387,769	$2,183,139
PODD	Insulet Corp	10,000	$2,098,400
CRL	Charles River Laboratories International, Inc.	10,000	$1,725,000
CRVS	Corvus Pharmaceuticals, Inc.	115,000	$1,682,450
HIMS	Hims & Hers Health, Inc.	75,000	$1,557,000
RVMD	Revolution Medicines, Inc.	15,000	$1,458,750
GPCR	Structure Therapeutics Inc.	30,000	$1,446,000
TEM	Tempus AI, Inc.	25,000	$1,130,500
ABVX	Abivax S.A.	10,000	$1,113,500
UNH	Unitedhealth Group Inc	3,800	$1,028,242
ABT	Abbott Laboratories	10,000	$1,026,700
NTLA	Intellia Therapeutics, Inc.	75,000	$961,500
ODD	Oddity Tech Ltd	70,000	$936,600
MLTX	MoonLake Immunotherapeutics	50,000	$932,000
PTON	Peloton Interactive, Inc.	200,000	$858,000
AVR	Anteris Technologies Global Corp.	150,000	$832,500
BBIO	BridgeBio Pharma, Inc.	10,000	$742,600
ABUS	Arbutus Biopharma Corp	125,000	$562,500
BBOT	BridgeBio Oncology Therapeutics, Inc.	43,853	$392,484
No positions match the current search.

Sold Out

Positions the filer fully exited

15 positions

Ticker	Company	Shares	Value
ALNY	Alnylam Pharmaceuticals, Inc.	21,000	$8,350,650
MCK	Mckesson Corp	9,520	$7,809,160
A	Agilent Technologies, Inc.	41,500	$5,646,905
PFE	Pfizer Inc	203,600	$5,069,640
DHR	Danaher Corp /De/	17,000	$3,891,640
TMO	Thermo Fisher Scientific Inc.	6,700	$3,882,315
NVO	Novo Nordisk A S	67,300	$3,424,224
CI	Cigna Group	11,600	$3,192,668
COR	Cencora, Inc.	9,400	$3,174,850
INSM	INSMED Inc	17,700	$3,080,508
WAT	Waters Corp /De/	8,100	$3,076,623
ACHC	Acadia Healthcare Company, Inc.	169,000	$2,398,110
ITGR	Integer Holdings Corp	29,800	$2,337,214
HQY	Healthequity, Inc.	16,900	$1,548,209
IQV	Iqvia Holdings Inc.	4,400	$991,804
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

52 positions · $584,570,627 total · as of Mar 31, 2026

All sectors Consumer Cyclical Consumer Defensive Healthcare

Showing 1–50 of 52 positions by value · page 1 of 2

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	Held	2,104,184	0	$176,583,121	+103.6%	30.21%
CGON	CG Oncology, Inc. Healthcare	Reduced	1,288,948	-183,751	$87,236,000	+42.7%	14.92%
IMUX	Immunic, Inc. Healthcare	Added	6,699,411	+2,000,000	$74,363,462	+196.3%	12.72%
ORKA	Oruka Therapeutics, Inc. Healthcare	Added	760,424	+100,000	$37,298,797	+86.3%	6.38%
CATX	Perspective Therapeutics, Inc. Healthcare	Added	6,049,999	+2,839,266	$25,228,495	+185.7%	4.32%
JBIO	Jade Biosciences, Inc. Healthcare	Held	1,400,708	0	$19,679,947	−8.9%	3.37%
ELVN	Enliven Therapeutics, Inc. Healthcare	Added	400,000	+259,700	$15,680,000	+625.7%	2.68%
SCYX	Scynexis Inc Healthcare	Reduced	2,081,660	-4,426,565	$15,271,057	+14.6%	2.61%
TEVA	Teva Pharmaceutical Industries Ltd Healthcare	Added	450,100	+32,800	$13,557,012	+4.1%	2.32%
CNTX	Context Therapeutics Inc. Healthcare	Reduced	4,998,267	-506,588	$13,095,459	+61.8%	2.24%
RGEN	Repligen Corp Healthcare	Added	77,800	+27,500	$9,166,396	+11.2%	1.57%
PVLA	Palvella Therapeutics, Inc. Healthcare	Added	70,000	+50,700	$8,725,500	+331.9%	1.49%
MDT	Medtronic plc Healthcare	Reduced	100,000	-7,600	$8,665,000	−16.2%	1.48%
VIR	Vir Biotechnology, Inc. Healthcare	NEW	950,000	NEW	$8,512,000	NEW	1.46%
AKTS	Aktis Oncology, Inc. Healthcare	NEW	468,566	NEW	$8,382,645	NEW	1.43%
DXCM	Dexcom Inc Healthcare	NEW	90,000	NEW	$5,652,000	NEW	0.97%
HUM	Humana Inc Healthcare	NEW	25,000	NEW	$4,334,750	NEW	0.74%
EHC	Encompass Health Corp Healthcare	Added	42,000	+10,400	$4,062,660	+21.1%	0.69%
BSX	Boston Scientific Corp Healthcare	Reduced	60,000	-54,500	$3,765,000	−65.5%	0.64%
TENX	Tenax Therapeutics, Inc. Healthcare	NEW	215,934	NEW	$3,452,784	NEW	0.59%
GILD	Gilead Sciences, Inc. Healthcare	NEW	20,000	NEW	$2,787,400	NEW	0.48%
PHAT	Phathom Pharmaceuticals, Inc. Healthcare	Added	249,390	+43,314	$2,770,722	−19.0%	0.47%
KPTI	Karyopharm Therapeutics Inc. Healthcare	Added	463,741	+329,175	$2,583,037	+160.8%	0.44%
CNC	Centene Corp Healthcare	Reduced	70,000	-49,400	$2,291,800	−53.4%	0.39%
MSLE	Satellos Bioscience Inc. Healthcare	NEW	387,769	NEW	$2,183,139	NEW	0.37%
PODD	Insulet Corp Healthcare	NEW	10,000	NEW	$2,098,400	NEW	0.36%
NTRA	Natera, Inc. Healthcare	Reduced	9,000	-2,800	$1,799,910	−33.4%	0.31%
ICLR	Icon PLC Healthcare	Reduced	16,000	-17,100	$1,770,560	−70.6%	0.30%
CRL	Charles River Laboratories International, Inc. Healthcare	NEW	10,000	NEW	$1,725,000	NEW	0.30%
KVUE	Kenvue Inc. Consumer Defensive	Reduced	100,000	-132,800	$1,724,000	−57.1%	0.29%
CRVS	Corvus Pharmaceuticals, Inc. Healthcare	NEW	115,000	NEW	$1,682,450	NEW	0.29%
HIMS	Hims & Hers Health, Inc. Healthcare	NEW	75,000	NEW	$1,557,000	NEW	0.27%
RVMD	Revolution Medicines, Inc. Healthcare	NEW	15,000	NEW	$1,458,750	NEW	0.25%
GPCR	Structure Therapeutics Inc. Healthcare	NEW	30,000	NEW	$1,446,000	NEW	0.25%
GMAB	Genmab A/S Healthcare	Reduced	50,000	-42,000	$1,341,500	−52.7%	0.23%
CORT	Corcept Therapeutics Inc Healthcare	Added	30,000	+8,000	$1,209,300	+58.0%	0.21%
TEM	Tempus AI, Inc. Healthcare	NEW	25,000	NEW	$1,130,500	NEW	0.19%
ABVX	Abivax S.A. Healthcare	NEW	10,000	NEW	$1,113,500	NEW	0.19%
UNH	Unitedhealth Group Inc Healthcare	NEW	3,800	NEW	$1,028,242	NEW	0.18%
ABT	Abbott Laboratories Healthcare	NEW	10,000	NEW	$1,026,700	NEW	0.18%
NTLA	Intellia Therapeutics, Inc. Healthcare	NEW	75,000	NEW	$961,500	NEW	0.16%
ODD	Oddity Tech Ltd Consumer Defensive	NEW	70,000	NEW	$936,600	NEW	0.16%
MLTX	MoonLake Immunotherapeutics Healthcare	NEW	50,000	NEW	$932,000	NEW	0.16%
PTON	Peloton Interactive, Inc. Consumer Cyclical	NEW	200,000	NEW	$858,000	NEW	0.15%
AVR	Anteris Technologies Global Corp. Healthcare	NEW	150,000	NEW	$832,500	NEW	0.14%
BBIO	BridgeBio Pharma, Inc. Healthcare	NEW	10,000	NEW	$742,600	NEW	0.13%
ABUS	Arbutus Biopharma Corp Healthcare	NEW	125,000	NEW	$562,500	NEW	0.10%
BBOT	BridgeBio Oncology Therapeutics, Inc. Healthcare	NEW	43,853	NEW	$392,484	NEW	0.07%
ACAD	Acadia Pharmaceuticals Inc Healthcare	Reduced	12,967	-93,933	$288,645	−89.9%	0.05%
SVRA	Savara Inc Healthcare	NEW	50,000	NEW	$273,000	NEW	0.05%