GPCR · Structure Therapeutics Inc. · Holdings

$21.19 -0.74 (-3.37%) At close · Oct 23

Market Cap

$1.51B

71.31M

Volume · Oct 23 798.11K Avg daily vol (3M) 1.06M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP → See every holder of GPCR: 13F, 13D and 13G, insiders and funds →

Recent SEC filings are still being reconciled. Holder totals and changes may be incomplete until processing catches up.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 193

Total Value: $3,651,869,606

Total Shares: 68,076,210

Showing 1–100 of 199 holdings by value · page 1 of 2

Institutional Ownership Trend

15 quarters

Holder Concentration

Across 194 13F filers

Top Holder

11.5%

of institutional value

Top 5

46.5%

of institutional value

Top 10

63.9%

of institutional value

HHI

550

Broadly held

Who Holds GPCR

Last 8 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 191 filers, like-for-like change +1.3%; actively managed books 0.0%; index-like books +23.4%.

Holder type	Share	Filers	Change	New	Exited
Registered adviser	33.4%	91	+2.2%	14	20
Exempt adviser	0.8%	7	+74.1%	1	1
Adviser	8.5%	8	+6.1%	0	1
Bank	1.9%	13	+18.3%	1	1
Insurer	2.6%	1	-0.1%	0	0
Broker-dealer	0.0%	2	+20.7%	0	0
Non-US	1.2%	9	-10.6%	2	0
Holding company	28.9%	10	+1.7%	1	0
Benefit plan	0.0%	0	—	0	0
Unknown	22.7%	50	-3.9%	8	8

Style	Share	Filers	Change	New	Exited
Index-like	6.6%	9	+23.4%	1	0
Systematic-like	1.6%	13	-37.4%	3	7
Concentrated	21.0%	29	-3.7%	1	8
Diversified active	70.8%	140	+2.5%	22	16
Not measured	0.0%	0	—	0	0
Unknown	0.0%	0	—	0	0

Turnover	Share	Filers	Change	New	Exited
Low turnover	48.1%	84	-2.8%	8	9
Medium turnover	36.1%	52	+11.5%	7	7
High turnover	4.6%	39	-23.2%	10	14
Unknown	11.2%	16	+3.0%	2	1
Not measured	0.0%	0	—	0	0

Holding horizon	Share	Filers	Change	New	Exited
Short horizon	12.4%	32	-1.1%	9	11
Medium horizon	11.3%	28	-6.1%	3	3
Long horizon	65.8%	109	+2.3%	14	11
Unknown	10.5%	22	+6.2%	1	6
Not measured	0.0%	0	—	0	0

13F book size	Share	Filers	Change	New	Exited
Under $1B	3.7%	39	+6.7%	6	10
$1B to $10B	25.8%	57	+3.3%	8	10
$10B to $100B	22.5%	49	+6.6%	12	10
$100B or more	48.1%	46	-2.4%	1	1
Not measured	0.0%	0	—	0	0

Client base	Share	Filers	Change	New	Exited
Individuals and high net worth	0.3%	31	+15.1%	6	3
Pooled investment vehicles	27.2%	44	+9.0%	7	10
Registered funds and BDCs	1.6%	6	-51.1%	1	2
Pension and profit sharing plans	0.0%	0	—	0	0
Insurance companies	0.1%	1	0.0%	0	0
Governments and sovereign funds	0.7%	1	+90.3%	0	1
Other investment advisers	0.0%	2	-16.0%	0	0
Diversified	3.6%	5	-7.3%	0	3
Corporations	0.0%	0	-100.0%	0	1
Other	0.0%	0	—	0	0
Unknown	66.6%	101	+0.8%	13	11

Private funds	Share	Filers	Change	New	Exited
Hedge funds	14.8%	43	+14.0%	8	12
Private equity funds	0.2%	5	-40.3%	1	0
Venture capital funds	1.1%	2	+2.8%	0	0
Other private funds	4.5%	5	-13.1%	1	1
Mixed private funds	12.6%	5	-0.7%	0	0
No private funds	0.9%	36	+11.0%	4	6
Real estate funds	0.0%	1	-93.9%	1	1
Private funds, type not stated	0.0%	0	-100.0%	0	1
Securitized asset funds	0.0%	0	—	0	0
Unknown	65.8%	94	+0.3%	12	10

Location	Share	Filers	Change	New	Exited
United States	94.3%	148	+0.7%	20	29
Outside the US	5.7%	43	+10.9%	7	2

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Excluded 1 holder with no observed 2026-06-30 13F. Compared across CIK changes: JANUS HENDERSON GROUP PLC continues as Jupiter Topco LLC.

Conviction and Crowding

191 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders

4.71% of filers hold it in their top 10

Mar 31, 2026: 9

Holders above 5%

median weight 0.010%

Mar 31, 2026: 1

Crowding

10.7%

of shares outstanding, 33rd percentile

Mar 31, 2026: 10.7%

Private-fund advisers

10.6%

of shares outstanding

Institutional ownership

31.7%

32.7% of the estimated free float

Top 10 holders

64.4%

of 13F shares, Herfindahl 0.056

Active holders

0.0%

like-for-like share change of active filers

5% stakes on record

0 13D, 5 13G (3 institutional, 2 passive, 0 exempt)

How long holders have held it value-weighted 9.3 quarters

Under 1 year 19.1% 1 to 3 years 30.7% 3 years or more 50.2% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net sellers of $3,098,467 (1 buying, 1 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost

$38.55

estimated per share

Mar 31, 2026: $38.69

Quarter-end price

$53.67

implied by 13F values

Estimated gain or loss

+39.2%

price against the estimated cost

Estimated at a loss

3.69%

of costed 13F value

Estimated cost covers 98.1% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies GPCR's active holders also own, quarter ended Jun 30, 2026

#	Company	Shared holders	Similarity
1	XENE Xenon Pharmaceuticals Inc.	21	0.405
2	MLYS Mineralys Therapeutics, Inc.	17	0.366
3	TNGX Tango Therapeutics, Inc.	17	0.362
4	STOK Stoke Therapeutics, Inc.	12	0.354
5	ELVN Enliven Therapeutics, Inc.	17	0.347
6	AVTX Avalo Therapeutics, Inc.	15	0.347
7	COGT Cogent Biosciences, Inc.	19	0.340
8	DFTX Definium Therapeutics, Inc.	20	0.338
9	DNTH Dianthus Therapeutics, Inc.	17	0.334
10	MBX MBX Biosciences, Inc.	13	0.322

Shareholder Targets

13F filers that own its peers but not GPCR, quarter ended Jun 30, 2026

Found through its holder-overlap peers: XENE, MLYS, TNGX, STOK, ELVN, AVTX, COGT, DFTX, DNTH, MBX, VERA, PRAX, SNDX, ERAS, PALI, RCUS, IDYA, OLMA, IRON, ORKA. 693 filers in all.

#	Filer	In peers	Of book	Largest peers
1	VANGUARD CAPITAL MANAGEMENT LLC Registered adviser, Index-like	$2,641,687,221 20 held	0.060%	PRAX, COGT, ORKA
2	VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser, Diversified active	$1,459,922,956 20 held	0.070%	PRAX, COGT, RCUS
3	Polar Capital Holdings Plc Registered adviser, Diversified active	$1,274,283,067 11 held	3.62%	ELVN, XENE, COGT
4	T. Rowe Price Investment Management, Inc. Adviser, Diversified active	$1,177,186,320 9 held	0.770%	ERAS, DNTH, XENE
5	GILEAD SCIENCES, INC. Unknown, Concentrated	$968,825,350 1 held	58.7%	RCUS
6	PERCEPTIVE ADVISORS LLC Registered adviser, Diversified active	$941,558,819 6 held	15.2%	PRAX, ORKA, TNGX
7	Venrock Adviser, LLC Registered adviser, Concentrated	$927,873,409 5 held	28.1%	ORKA, ERAS, DNTH
8	Frazier Life Sciences Management, L.P. Registered adviser, Concentrated	$923,830,436 3 held	20.1%	ERAS, MBX, IRON
9	Fairmount Funds Management LLC Registered adviser, Concentrated	$907,111,371 4 held	60.0%	ORKA, DNTH, COGT
10	TCG Crossover Management, LLC Unknown, Diversified active	$824,962,486 6 held	19.8%	TNGX, COGT, DNTH

Fund Ownership of GPCR by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 0.90% of shares outstanding.

Fund type	Of shares outstanding	Change	Shares	Funds
Index funds	0.11%	+0.05 pp	77,781	5
Index ETFs	0.79%	+0.07 pp	564,170	9
Active ETFs	0.16%	-0.08 pp	117,467	7
Active funds	20.44%	+1.10 pp	14,572,859	113
Unclassified	0.70%	+0.69 pp	495,902	10
All registered funds	22.20%	+1.84 pp	15,828,179	144

How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Holder type: Registered adviser 93 Exempt adviser 7 Adviser 8 Bank 13 Insurer 1 Broker-dealer 2 Non-US 9 Holding company 10 Unknown 50

Showing 100 of 199

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

FMR LLC

$419,179,120

11.48%

7,810,306

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC joint	6,434,598	$345,344,874	82.4%	Defined
FIDELITY MANAGEMENT TRUST CO	425,930	$22,859,663	5.5%	Defined
Impresa Management LLC	34,907	$1,873,458	0.4%	Defined
Fidelity Institutional Asset Management Trust Co	413,595	$22,197,643	5.3%	Defined
FIAM LLC	501,276	$26,903,482	6.4%	Defined

WELLINGTON MANAGEMENT GROUP LLP

$396,054,165

10.85%

7,379,433

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	6,347,592	$340,675,262	86.0%	Defined
Wellington Managment Canada LLC	81,990	$4,400,403	1.1%	Defined
Wellington Management Japan Pte Ltd	82,466	$4,425,950	1.1%	Defined
Wellington Management Singapore Pte. Ltd.	68,061	$3,652,833	0.9%	Defined
Wellington Management International Ltd	161,723	$8,679,673	2.2%	Defined
Wellington Trust Company, NA joint	556,354	$29,859,519	7.5%	Defined
Wellington Management Australia Pty Ltd	13,364	$717,245	0.2%	Defined
Wellington Management Europe GmbH	67,883	$3,643,280	0.9%	Defined

Avoro Capital Advisors LLC

$351,836,636

9.63%

6,555,555

Jupiter Topco LLC

$279,310,056

7.65%

5,204,212

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	92,532	$4,966,192	1.8%	Defined
JANUS HENDERSON INVESTORS US LLC	5,049,980	$271,032,426	97.0%	Defined
Janus Henderson Investors (Singapore) Ltd	54,531	$2,926,678	1.0%	Defined
Held directly	7,169	$384,760	0.1%	Defined

Deep Track Capital, LP

$254,399,664

6.97%

4,740,072

BVF INC/IL

$180,697,390

4.95%

3,366,823

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BVF PARTNERS L P/IL	3,366,823	$180,697,390	100.0%	Defined

MORGAN STANLEY

$150,632,366

4.12%

2,806,640

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	12	$644	0.0%	Defined
MORGAN STANLEY & CO. LLC	11,981	$643,020	0.4%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	2,444,657	$131,204,741	87.1%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	63,348	$3,399,887	2.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	274,160	$14,714,166	9.8%	Defined
Morgan Stanley Bank, N.A.	4,445	$238,563	0.2%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	8,037	$431,345	0.3%	Defined

ORBIMED ADVISORS LLC

$118,578,498

3.25%

2,209,400

PRINCIPAL FINANCIAL GROUP INC

$94,070,253

2.58%

1,752,753

AMERICAN CENTURY COMPANIES INC

$90,282,546

2.47%

1,682,179

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	1,682,179	$90,282,546	100.0%	Defined

RTW INVESTMENTS, LP

$86,274,900

2.36%

1,607,507

Driehaus Capital Management LLC

$83,361,263

2.28%

1,553,219

BAKER BROS. ADVISORS LP

$76,883,831

2.11%

1,432,529

Casdin Capital, LLC

$63,062,250

1.73%

1,175,000

DEERFIELD MANAGEMENT COMPANY, L.P.

$58,285,620

1.60%

1,086,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deerfield UGP, LLC	1,086,000	$58,285,620	100.0%	Defined

CAPITOLIS LIQUID GLOBAL MARKETS LLC

$55,875,837

1.53%

1,041,100

Siren, L.L.C.

$46,852,138

1.28%

872,967

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	872,967	$46,852,138	100.0%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$45,379,702

1.24%

845,532

Pacific Heights Asset Management LLC

$42,936,000

1.18%

800,000

Rock Springs Capital Management LP

$34,365,813

0.94%

640,317

Aberdeen Group plc

$34,344,238

0.94%

639,915

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	639,915	$34,344,238	100.0%	Defined

ALLIANCEBERNSTEIN L.P.

$32,830,368

0.90%

611,708

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	611,708	$32,830,368	100.0%	Defined

FRANKLIN RESOURCES INC

$31,066,287

0.85%

578,839

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fiduciary Trust Co International of Pennsylvania	50	$2,683	0.0%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	292	$15,671	0.1%	Defined
FRANKLIN ADVISERS INC	578,497	$31,047,933	99.9%	Defined

BANK OF AMERICA CORP /DE/

$30,238,857

0.83%

563,422

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	234,383	$12,579,335	41.6%	Defined
BOFA SECURITIES, INC.	299,799	$16,090,212	53.2%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	29,240	$1,569,310	5.2%	Defined

BlackRock, Inc.

$27,433,361

0.75%

511,149

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	5,540	$297,331	1.1%	Sole
BLACKROCK ADVISORS LLC	19,786	$1,061,914	3.9%	Sole
BlackRock Fund Advisors	418,591	$22,465,778	81.9%	Sole
BlackRock Investment Management (UK) Ltd.	7,792	$418,196	1.5%	Sole
BlackRock (Netherlands) B.V.	973	$52,220	0.2%	Sole
BlackRock Asset Management Ireland Ltd	57,795	$3,101,857	11.3%	Sole
BlackRock (Luxembourg) S.A.	429	$23,024	0.1%	Sole
Aperio Group, LLC	243	$13,041	0.0%	Sole

Logos Global Management LP

$26,835,000

0.73%

500,000

Parkman Healthcare Partners LLC

$26,065,425

0.71%

485,661

Davern Capital Partners, LP

$23,939,986

0.66%

446,059

HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND

$22,476,996

0.62%

418,800

UBS Group AG

$20,340,178

0.56%

378,986

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	518	$27,801	0.1%	Defined
UBS AG	378,468	$20,312,377	99.9%	Defined

DEUTSCHE BANK AG\

$17,811,301

0.49%

331,867

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS Investments UK Ltd	331,867	$17,811,301	100.0%	Defined

NEXTBio Capital Management LP

$16,771,660

0.46%

312,496

Catalio Capital Management, LP

$14,842,438

0.41%

276,550

MARSHALL WACE, LLP

$14,361,662

0.39%

267,592

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	267,592	$14,361,662	100.0%	Other

HSG Holding Ltd

$14,279,547

0.39%

266,062

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SNP China Enterprises Ltd	266,062	$14,279,547	100.0%	Defined

SEB Asset Management AB

$13,151,457

0.36%

245,043

GOLDMAN SACHS GROUP INC

$13,030,538

0.36%

242,790

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	233,294	$12,520,888	96.1%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	9,496	$509,650	3.9%	Defined

AMERIPRISE FINANCIAL INC

$12,371,684

0.34%

230,514

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	39,457	$2,117,657	17.1%	Defined
Threadneedle Asset Management Holdings LTD	185,094	$9,933,994	80.3%	Defined
Ameriprise Financial Services, LLC	305	$16,369	0.1%	Defined
Columbia Threadneedle Management Ltd	5,658	$303,664	2.5%	Defined

NATIONAL BANK OF CANADA /FI/

$11,581,986

0.32%

215,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NBC Global Finance Ltd	215,800	$11,581,986	100.0%	Defined

TWO SIGMA INVESTMENTS, LP

$10,957,052

0.30%

204,156

Eversept Partners, LP

$10,535,528

0.29%

196,302

Schonfeld Strategic Advisors LLC

$10,234,063

0.28%

190,685

Woodline Partners LP

$8,254,875

0.23%

153,808

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$8,217,896

0.23%

153,119

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	153,119	$8,217,896	100.0%	Defined

ArrowMark Colorado Holdings LLC

$8,081,574

0.22%

150,579

Susquehanna Portfolio Strategies, LLC

$7,994,039

0.22%

148,948

CenterBook Partners LP

$7,944,770

0.22%

148,030

Rhenman & Partners Asset Management AB

$7,787,517

0.21%

145,100

GOLDMAN SACHS GROUP INC

$7,782,150

0.21%

145,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	145,000	$7,782,150	100.0%	Defined

B Group, Inc.

$7,513,800

0.21%

140,000

HighVista Strategies LLC

$7,019,177

0.19%

130,784

Universal- Beteiligungs- und Servicegesellschaft mbH

$6,745,728

0.18%

125,689

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH joint	125,689	$6,745,728	100.0%	Defined

Squarepoint Ops LLC

$6,739,610

0.18%

125,575

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	125,575	$6,739,610	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$6,566,202

0.18%

122,344

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	122,344	$6,566,202	100.0%	Other

D. E. Shaw & Co., Inc.

$6,188,151

0.17%

115,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	115,300	$6,188,151	100.0%	Defined

VOLORIDGE INVESTMENT MANAGEMENT, LLC

$6,027,141

0.17%

112,300

Soleus Capital Management, L.P.

$5,742,690

0.16%

107,000

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$5,302,596

0.15%

98,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	98,800	$5,302,596	100.0%	Other

Avidity Partners Management LP

$5,259,660

0.14%

98,000

GEODE CAPITAL MANAGEMENT, LLC

$5,215,811

0.14%

97,183

Qube Research & Technologies Ltd

$5,012,939

0.14%

93,403

PEREGRINE CAPITAL MANAGEMENT LLC

$4,949,930

0.14%

92,229

PFM Health Sciences, LP

$4,913,488

0.13%

91,550

PLATINUM INVESTMENT MANAGEMENT LTD

$4,849,782

0.13%

90,363

MILLENNIUM MANAGEMENT LLC

$4,807,114

0.13%

89,568

ExodusPoint Capital Management, LP

$4,200,536

0.12%

78,266

Boxer Capital Management, LLC

$4,025,250

0.11%

75,000

Cormorant Asset Management, LP

$4,025,250

0.11%

75,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Chen Bihua	75,000	$4,025,250	100.0%	Defined

ADAGE CAPITAL PARTNERS GP, L.L.C.

$4,025,250

0.11%

75,000

CITADEL ADVISORS LLC

$4,014,516

0.11%

74,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	74,800	$4,014,516	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$3,869,607

0.11%

72,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	72,100	$3,869,607	100.0%	Other

ALPS ADVISORS INC

$3,855,277

0.11%

71,833

TD Asset Management Inc

$3,701,190

0.10%

68,962

Brevan Howard Capital Management LP

$3,238,233

0.09%

60,336

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Brevan Howard Investment Products Ltd	60,336	$3,238,233	100.0%	Defined

Burkehill Global Management, LP

$3,220,200

0.09%

60,000

RAYMOND JAMES FINANCIAL INC

$3,185,689

0.09%

59,357

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	438	$23,507	0.7%	Defined
Raymond James Financial Services Advisors, Inc.	3,235	$173,622	5.5%	Defined
CHARTWELL INVESTMENT PARTNERS, LLC	55,684	$2,988,560	93.8%	Defined

JANE STREET GROUP, LLC

$3,026,988

0.08%

56,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	56,400	$3,026,988	100.0%	Defined

CITADEL ADVISORS LLC

$2,908,914

0.08%

54,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	54,200	$2,908,914	100.0%	Defined

TUDOR INVESTMENT CORP ET AL

$2,879,717

0.08%

53,656

ANTIPODES PARTNERS Ltd

$2,751,231

0.08%

51,262

Buckland Partners Management Co LLC

$2,683,500

0.07%

50,000

SCOGGIN MANAGEMENT LP

$2,683,500

0.07%

50,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Scoggin GP LLC	50,000	$2,683,500	100.0%	Defined

SEVEN GRAND MANAGERS, LLC

$2,683,500

0.07%

50,000

DAFNA Capital Management LLC

$2,495,655

0.07%

46,500

Mariner, LLC

$2,484,115

0.07%

46,285

OSAIC HOLDINGS, INC.

$2,403,664

0.07%

44,786

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	39,414	$2,115,349	88.0%	Defined
CW Advisors, LLC	5,372	$288,315	12.0%	Sole

STATE STREET CORP

$2,395,238

0.07%

44,629

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	44,629	$2,395,238	100.0%	Defined

VOYA INVESTMENT MANAGEMENT LLC

$2,383,484

0.07%

44,410

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	44,410	$2,383,484	100.0%	Defined

Jump Financial, LLC

$2,289,454

0.06%

42,658

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Leap GP LLC joint	42,658	$2,289,454	100.0%	Defined

BANK OF MONTREAL /CAN/

$2,284,730

0.06%

42,570

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMO Bank N.A.	7	$375	0.0%	Defined
BMO NESBITT BURNS INC.	42,413	$2,276,305	99.6%	Defined
BMO NESBITT BURNS SECURITIES LTD.	150	$8,050	0.4%	Defined

Cinctive Capital Management LP

$2,193,868

0.06%

40,877

Jefferies Financial Group Inc.

$2,180,343

0.06%

40,625

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jefferies Financial Services, Inc.	40,625	$2,180,343	100.0%	Defined

Jones Hill Capital LP

$2,177,230

0.06%

40,567

STEMPOINT CAPITAL LP

$2,049,013

0.06%

38,178

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$2,045,256

0.06%

38,108

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	38,108	$2,045,256	100.0%	Defined

CAPITAL FUND MANAGEMENT S.A.

$2,000,871

0.05%

37,281

PSquared Asset Management AG

$1,996,524

0.05%

37,200

FLAX POND CAPITAL, LLC

$1,932,120

0.05%

36,000

TrueMark Investments, LLC

$1,803,312

0.05%

33,600

NOMURA ASSET MANAGEMENT CO LTD

$1,759,839

0.05%

32,790

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nomura Asset Management Europe KVG mbH	32,790	$1,759,839	100.0%	Sole
Held directly	0	$0	0.0%	Sole

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Key facts CIK 1888886 CUSIP 86366E106 13F (30d) 14 filings 14 filers Visit website Investor relations