Driehaus Capital Management LLC
Position in GPCR — Structure Therapeutics Inc.
CIK 938206
Chicago, IL
Position in GPCR
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$83,361,263
+$7,332,704 QoQ
Shares Held
1,553,219
-1.5% QoQ
Ownership
2.18%
of shares outstanding
% of Portfolio
0.48%
of 13F equity value
Holder Rank
#12
of 190 holders
Holding Since
Mar 2023
14 quarters on record
Voting authority
Sole 83%
Shared 0%
None 17%
Common Shares in GPCR Over Time
Shares Held
Position Value (USD)
Derivatives in GPCR
reported options exposure · as of Dec 31, 2023CallValue
$0
CallShares
0
PutValue
$6,440,080
PutShares
158,000
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Jun 30, 2026Driehaus Capital Management LLC holds $3,707,249,767 across 60 Biotechnology names. GPCR ranks #17 (2.2% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | DFTX |
Definium Therapeutics, Inc.
|
6,845,276 | $322,001,783 | |
| 2 | PRAX |
Praxis Precision Medicines, Inc.
|
959,048 | $321,079,679 | |
| 3 | XENE |
Xenon Pharmaceuticals Inc.
|
4,418,557 | $266,704,100 | |
| 4 | SYRE |
Spyre Therapeutics, Inc.
|
2,799,166 | $248,509,957 | |
| 5 | CRNX |
Crinetics Pharmaceuticals, Inc.
|
6,463,551 | $241,866,078 | |
| 6 | APGE |
Apogee Therapeutics, Inc.
|
1,740,101 | $230,963,605 | |
| 7 | EWTX |
Edgewise Therapeutics, Inc.
|
4,728,623 | $192,123,952 | |
| 8 | SEPN |
Septerna, Inc.
|
4,433,058 | $148,463,112 |
All Filings in GPCR
Export CSV
15 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $83,361,263 | 1,553,219 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $76,028,559 | 1,577,356 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $114,231,980 | 1,642,444 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $24,458,112 | 873,504 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $13,953,706 | 672,792 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $22,031,181 | 1,272,743 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $55,796,959 | 2,057,410 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $110,885,012 | 2,526,430 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $101,204,130 | 2,577,136 | Shares | Sole | 2024-08-15 | |
| 2024-03-31 | $106,734,386 | 2,490,303 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $6,440,080 | 158,000 | Put | Sole | 2024-02-14 | |
| 2023-12-31 | $105,938,460 | 2,599,079 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $120,447,127 | 2,388,876 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $47,220,859 | 1,135,936 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $22,368,024 | 940,228 | Shares | Sole | 2023-05-15 | |
| No filing history on record for this holder in this stock. | ||||||