Driehaus Capital Management LLC

Position in SEPN — Septerna, Inc.

CIK 938206 Chicago, IL

Position in SEPN

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$148,463,112

+$42,837,517 QoQ

Shares Held

4,433,058

+0.9% QoQ

Ownership

9.50%

of shares outstanding

% of Portfolio

0.86%

of 13F equity value

Holder Rank

of 154 holders

Holding Since

Dec 2024

7 quarters on record

Voting authority Sole 85% Shared 0% None 15%

Healthcare · as of Jun 30, 2026

Driehaus Capital Management LLC holds $3,602,052,293 across 59 Biotechnology names. SEPN ranks #8 (4.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	DFTX	Definium Therapeutics, Inc.	6,845,276	$322,001,783
2	PRAX	Praxis Precision Medicines, Inc.	959,048	$321,079,679
3	XENE	Xenon Pharmaceuticals Inc.	4,418,557	$266,704,100
4	SYRE	Spyre Therapeutics, Inc.	2,799,166	$248,509,957
5	CRNX	Crinetics Pharmaceuticals, Inc.	6,463,551	$241,866,078
6	APGE	Apogee Therapeutics, Inc.	1,740,101	$230,963,605
7	EWTX	Edgewise Therapeutics, Inc.	4,728,623	$192,123,952
8	SEPN	Septerna, Inc. This page	4,433,058	$148,463,112

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$148,463,112	4,433,058	+0.9%	Shares	Sole	2026-08-14
2026-06-30	$148,463,112	4,433,058	-4.9%	Shares	Sole	2026-08-14
2026-03-31	$105,625,595	4,395,572	-8.6%	Shares	Sole	2026-05-15
2025-12-31	$134,088,023	4,809,470	-2.2%	Shares	Sole	2026-02-17
2025-09-30	$92,543,243	4,919,896	+5.1%	Shares	Sole	2025-11-14
2025-06-30	$49,472,155	4,680,431	+49.9%	Shares	Sole	2025-08-14
2025-05-31	$43,104,176	4,659,911	+49.2%	Shares	Sole	2025-06-10
2025-03-31	$18,079,900	3,122,608	+20.6%	Shares	Sole	2025-05-15
2025-03-31	$18,079,900	3,122,608	+20.6%	Shares	Sole	2025-05-15
2024-12-31	$59,300,763	2,589,553	—	Shares	Sole	2025-02-14
2024-12-31	$59,300,763	2,589,553	—	Shares	Sole	2025-02-14
No filing history on record for this holder in this stock.