Driehaus Capital Management LLC

Position in SEPN — Septerna, Inc.

CIK 938206 Chicago, IL

Position in SEPN

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$105,625,595

-$28,462,428 QoQ

Shares Held

4,395,572

-8.6% QoQ

Ownership

9.75%

of shares outstanding

% of Portfolio

0.78%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Dec 2024

6 quarters on record

Voting authority Sole 84.3703845597342.ToString("F0")% Shared 0.ToString("F0")% None 15.629615440265795.ToString("F0")%

Healthcare · as of Mar 31, 2026

Driehaus Capital Management LLC holds $3,010,622,183 across 56 Biotechnology names. SEPN ranks #8 (3.5% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	PRAX	Praxis Precision Medicines, Inc.	949,225	$305,830,802
2	XENE	Xenon Pharmaceuticals Inc.	4,491,653	$261,189,621
3	CRNX	Crinetics Pharmaceuticals, Inc.	6,395,922	$232,299,887
4	APGE	Apogee Therapeutics, Inc.	1,920,800	$161,673,736
5	EWTX	Edgewise Therapeutics, Inc.	4,477,942	$141,055,173
6	SYRE	Spyre Therapeutics, Inc.	2,790,785	$140,767,195
7	DFTX	Definium Therapeutics, Inc.	5,911,889	$111,734,702
8	SEPN	Septerna, Inc. This page	4,395,572	$105,625,595

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$105,625,595	4,395,572	-8.6%	Shares	Sole	2026-05-15
2025-12-31	$134,088,023	4,809,470	-2.2%	Shares	Sole	2026-02-17
2025-09-30	$92,543,243	4,919,896	+5.1%	Shares	Sole	2025-11-14
2025-06-30	$49,472,155	4,680,431	+0.4%	Shares	Sole	2025-08-14
2025-05-31	$43,104,176	4,659,911	+49.2%	Shares	Sole	2025-06-10
2025-03-31	$18,079,900	3,122,608	0.0%	Shares	Sole	2025-05-15
2025-03-31	$18,079,900	3,122,608	+20.6%	Shares	Sole	2025-05-15
2024-12-31	$59,300,763	2,589,553	0.0%	Shares	Sole	2025-02-14
2024-12-31	$59,300,763	2,589,553	—	Shares	Sole	2025-02-14
No filing history on record for this holder in this stock.