GPCR · Structure Therapeutics Inc. · Shareholders & Ownership

$21.93 -0.08 (-0.36%) At close · Oct 22

Market Cap

$1.56B

71.31M

Volume · Oct 22 701.35K Avg daily vol (3M) 1.06M

Every disclosed holder of GPCR in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.

How the holder list picks a filing →

Who Owns GPCR

13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positions

Holder group	Holders	Shares	% Out	Summed
Institutional (13F)	190	67,512,465	31.56%	Yes
Insiders (Forms 3, 4, 5)	0	0	0.00%	No
13D/G-only blocks	3	22,619,817	10.57%	Yes
Remaining	—	123,797,290	57.87%	Rest
Registered funds (N-PORT, not summed)	145	15,787,524	7.38%	No

Shares outstanding: 213,929,572, the issuer's latest cover-page count restated onto today's split basis.

Insiders are listed but not summed: the issuer has more than one class of common stock and Forms 3, 4 and 5 report one issuer-wide balance across them.

13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.

Holders of GPCR

One row per holder Every filing By ultimate parent

All 13F Funds Insiders 13D/G Non-US

#	Holder	Shares	% Out	Change	As of	Notes
1	BIOTECHNOLOGY VALUE FUND L P 13G CIK 918923 · Unknown · Dec 31, 2025 Rule 13d-1(c), passive investor	10,437,066	4.88%	+825,315	Dec 31, 2025	Rule 13d-1(c), passive investor
2	WELLINGTON MANAGEMENT GROUP LLP 13F CIK 902219 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	7,379,433	3.45%	+119,146	Jun 30, 2026	carried, not yet filed for the newest quarter
3	Avoro Capital Advisors LLC 13F CIK 1633313 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	6,555,555	3.06%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
4	Capital Research Global Investors 13G CIK 1422848 · Investment adviser · Mar 31, 2025 Rule 13d-1(b), qualified institution	6,492,435	3.03%	-4,098,915	Mar 31, 2025	Rule 13d-1(b), qualified institution
5	RA CAPITAL MANAGEMENT, L.P. 13G CIK 1346824 · Registered investment adviser · Sep 30, 2024 Rule 13d-1(c), passive investor	5,690,316	2.66%	-1,534,995	Sep 30, 2024	Rule 13d-1(c), passive investor
6	Jupiter Topco LLC 13F CIK 2146052 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	5,204,212	2.43%	-150,769	Jun 30, 2026	carried, not yet filed for the newest quarter
7	Deep Track Capital, LP 13F CIK 1856083 · Investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	4,740,072	2.22%	+460,224	Jun 30, 2026	carried, not yet filed for the newest quarter
8	BVF INC/IL 13F CIK 1056807 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	3,366,823	1.57%	-92,535	Jun 30, 2026	carried, not yet filed for the newest quarter
9	Yoon Jun Insider CIK 1962414 · Mar 19, 2026 CHIEF FINANCIAL OFFICER, issuer-wide, not summed	2,956,242	1.38%	+104,085	Mar 19, 2026	CHIEF FINANCIAL OFFICER, issuer-wide, not summed
10	Stevens Raymond C Insider CIK 1698149 · Mar 19, 2026 Director, issuer-wide, not summed	2,956,179	1.38%	+260,217	Mar 19, 2026	Director, issuer-wide, not summed
11	MORGAN STANLEY 13F CIK 895421 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	2,806,640	1.31%	+501,183	Jun 30, 2026	carried, not yet filed for the newest quarter
11.1	Inception Portfolio Fund S000002825 · Registered fund · Jun 30, 2026 MORGAN STANLEY INSTITUTIONAL FUND INC, not summed	16,316	0.01%	0	Jun 30, 2026	MORGAN STANLEY INSTITUTIONAL FUND INC, not summed
11.2	Vitality Portfolio Fund S000074797 · Registered fund · Mar 31, 2026 MORGAN STANLEY INSTITUTIONAL FUND INC, not summed	1,489	0.00%	—	Mar 31, 2026	MORGAN STANLEY INSTITUTIONAL FUND INC, not summed
12	ORBIMED ADVISORS LLC 13F CIK 1055951 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,209,400	1.03%	+733,997	Jun 30, 2026	carried, not yet filed for the newest quarter
13	PRINCIPAL FINANCIAL GROUP INC 13F CIK 1126328 · Insurance company · Jun 30, 2026 carried, not yet filed for the newest quarter	1,752,753	0.82%	-1,011	Jun 30, 2026	carried, not yet filed for the newest quarter
13.1	Global Emerging Markets Fund Fund S000007013 · Registered fund · Jul 31, 2026 Principal Funds, Inc, not summed	625,751	0.29%	0	Jul 31, 2026	Principal Funds, Inc, not summed
13.2	SmallCap Fund Fund S000007214 · Registered fund · Jul 31, 2026 Principal Funds, Inc, not summed	287,100	0.13%	-12,300	Jul 31, 2026	Principal Funds, Inc, not summed
13.3	Principal Capital Appreciation Fund Fund S000014238 · Registered fund · Jul 31, 2026 Principal Funds, Inc, not summed	211,327	0.10%	-83,122	Jul 31, 2026	Principal Funds, Inc, not summed
13.4	SmallCap Growth Fund I Fund S000007175 · Registered fund · Jul 31, 2026 Principal Funds, Inc, not summed	46,188	0.02%	-2,310	Jul 31, 2026	Principal Funds, Inc, not summed
13.5	SmallCap Account Fund S000007675 · Registered fund · Jun 30, 2026 Principal Variable Contract Funds, Inc, not summed	26,300	0.01%	-300	Jun 30, 2026	Principal Variable Contract Funds, Inc, not summed
14	AMERICAN CENTURY COMPANIES INC 13F CIK 748054 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	1,682,179	0.79%	+244,148	Jun 30, 2026	carried, not yet filed for the newest quarter
14.1	Heritage Fund Fund S000006206 · Registered fund · Jul 31, 2026 American Century Mutual Funds, Inc., not summed	967,353	0.45%	0	Jul 31, 2026	American Century Mutual Funds, Inc., not summed
15	RTW INVESTMENTS, LP 13F CIK 1493215 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,607,507	0.75%	+1,607,507	Jun 30, 2026	carried, not yet filed for the newest quarter
16	Driehaus Capital Management LLC 13F CIK 938206 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,553,219	0.73%	-24,137	Jun 30, 2026	carried, not yet filed for the newest quarter
16.1	Driehaus Small Cap Growth Fund Fund S000058261 · Registered fund · Jun 30, 2026 Driehaus Mutual Funds, not summed	137,401	0.06%	+13,429	Jun 30, 2026	Driehaus Mutual Funds, not summed
16.2	Driehaus Micro Cap Growth Fund Fund S000042829 · Registered fund · Jun 30, 2026 Driehaus Mutual Funds, not summed	84,699	0.04%	-948	Jun 30, 2026	Driehaus Mutual Funds, not summed
16.3	Driehaus Small/Mid Cap Growth Fund Fund S000068519 · Registered fund · Jun 30, 2026 Driehaus Mutual Funds, not summed	7,147	0.00%	+331	Jun 30, 2026	Driehaus Mutual Funds, not summed
17	BAKER BROS. ADVISORS LP 13F CIK 1263508 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,432,529	0.67%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
18	Casdin Capital, LLC 13F CIK 1534261 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,175,000	0.55%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
19	DEERFIELD MANAGEMENT COMPANY, L.P. 13F CIK 1009258 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,086,000	0.51%	+318,007	Jun 30, 2026	carried, not yet filed for the newest quarter
20	CAPITOLIS LIQUID GLOBAL MARKETS LLC 13F CIK 2094379 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	1,041,100	0.49%	-110,200	Jun 30, 2026	carried, not yet filed for the newest quarter
21	Siren, L.L.C. 13F CIK 2005245 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	872,967	0.41%	-455,731	Jun 30, 2026	carried, not yet filed for the newest quarter
22	PRICE T ROWE ASSOCIATES INC /MD/ 13F CIK 80255 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	845,532	0.40%	-1,155,164	Jun 30, 2026	carried, not yet filed for the newest quarter
22.1	T. Rowe Price Health Sciences Fund, Inc. Fund S000002088 · Registered fund · Jun 30, 2026 T. ROWE PRICE HEALTH SCIENCES FUND, INC., not summed	419,407	0.20%	-853,800	Jun 30, 2026	T. ROWE PRICE HEALTH SCIENCES FUND, INC., not summed
22.2	T. Rowe Price New Horizons Fund, Inc. Fund S000002106 · Registered fund · Jun 30, 2026 T. ROWE PRICE NEW HORIZONS FUND, INC., not summed	207,816	0.10%	-93	Jun 30, 2026	T. ROWE PRICE NEW HORIZONS FUND, INC., not summed
22.3	T. Rowe Price Health Sciences Portfolio Fund S000002083 · Registered fund · Jun 30, 2026 T. ROWE PRICE EQUITY SERIES, INC., not summed	25,918	0.01%	-51,693	Jun 30, 2026	T. ROWE PRICE EQUITY SERIES, INC., not summed
23	Pacific Heights Asset Management LLC 13F CIK 1323414 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	800,000	0.37%	+50,000	Jun 30, 2026	carried, not yet filed for the newest quarter
24	Rock Springs Capital Management LP 13F CIK 1595725 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	640,317	0.30%	+100	Jun 30, 2026	carried, not yet filed for the newest quarter
25	Aberdeen Group plc 13F CIK 1716774 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	639,915	0.30%	+248,106	Jun 30, 2026	carried, not yet filed for the newest quarter
26	ALLIANCEBERNSTEIN L.P. 13F CIK 1109448 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	611,708	0.29%	-27,105	Jun 30, 2026	carried, not yet filed for the newest quarter
26.1	AB Small Cap Growth Portfolio Fund S000010309 · Registered fund · Jun 30, 2026 AB CAP FUND, INC., not summed	142,364	0.07%	-28,695	Jun 30, 2026	AB CAP FUND, INC., not summed
26.2	AB DISCOVERY GROWTH FUND, INC. Fund S000010117 · Registered fund · Jun 30, 2026 AB DISCOVERY GROWTH FUND, INC., not summed	138,229	0.06%	-23,659	Jun 30, 2026	AB DISCOVERY GROWTH FUND, INC., not summed
26.3	Small Cap Core Portfolio Fund S000051867 · Registered fund · Jun 30, 2026 Bernstein Fund Inc, not summed	33,101	0.02%	+7,081	Jun 30, 2026	Bernstein Fund Inc, not summed
26.4	AB Small Cap Growth Portfolio Fund S000010435 · Registered fund · Jun 30, 2026 AB VARIABLE PRODUCTS SERIES FUND, INC., not summed	2,700	0.00%	-288	Jun 30, 2026	AB VARIABLE PRODUCTS SERIES FUND, INC., not summed
26.5	Tax-Aware Overlay A Portfolio Fund S000027648 · Registered fund · Jun 30, 2026 BERNSTEIN SANFORD C FUND INC, not summed	958	0.00%	+40	Jun 30, 2026	BERNSTEIN SANFORD C FUND INC, not summed
27	FRANKLIN RESOURCES INC 13F CIK 38777 · Investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	578,839	0.27%	+47,244	Jun 30, 2026	carried, not yet filed for the newest quarter
27.1	Franklin Small Cap Growth Fund Fund S000006889 · Registered fund · Jul 31, 2026 Franklin Strategic Series, not summed	178,989	0.08%	-6,234	Jul 31, 2026	Franklin Strategic Series, not summed
27.2	Franklin Biotechnology Discovery Fund Fund S000006882 · Registered fund · Jul 31, 2026 Franklin Strategic Series, not summed	136,424	0.06%	0	Jul 31, 2026	Franklin Strategic Series, not summed
28	BANK OF AMERICA CORP /DE/ 13F CIK 70858 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	563,422	0.26%	+336,290	Jun 30, 2026	carried, not yet filed for the newest quarter
29	Janus Henderson Global Life Sciences Fund Fund S000010494 · Registered fund · Jun 30, 2026 Janus Investment Fund, not summed	549,353	0.26%	-20,236	Jun 30, 2026	Janus Investment Fund, not summed
30	BlackRock, Inc. 13F CIK 2012383 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	511,149	0.24%	+69,174	Jun 30, 2026	carried, not yet filed for the newest quarter
30.1	iShares Biotechnology ETF Fund S000004350 · Registered fund · Jun 30, 2026 iShares Trust, not summed	414,261	0.19%	+32,585	Jun 30, 2026	iShares Trust, not summed
31	Logos Global Management LP 13F CIK 1792126 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	500,000	0.23%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
32	Parkman Healthcare Partners LLC 13F CIK 1777015 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	485,661	0.23%	+253,568	Jun 30, 2026	carried, not yet filed for the newest quarter
33	Janus Henderson Triton Fund Fund S000010485 · Registered fund · Jun 30, 2026 Janus Investment Fund, not summed	467,112	0.22%	+7,625	Jun 30, 2026	Janus Investment Fund, not summed
34	Davern Capital Partners, LP 13F CIK 2003147 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	446,059	0.21%	+319,598	Jun 30, 2026	carried, not yet filed for the newest quarter
35	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 13F CIK 1535845 · Non-US institution · Jun 30, 2026 carried, not yet filed for the newest quarter	418,800	0.20%	-49,000	Jun 30, 2026	carried, not yet filed for the newest quarter
36	Aggressive Growth Portfolio Fund S000006019 · Registered fund · Jul 31, 2026 PERMANENT PORTFOLIO FAMILY OF FUNDS, not summed	400,000	0.19%	0	Jul 31, 2026	PERMANENT PORTFOLIO FAMILY OF FUNDS, not summed
37	Permanent Portfolio Fund S000006016 · Registered fund · Jul 31, 2026 PERMANENT PORTFOLIO FAMILY OF FUNDS, not summed	400,000	0.19%	0	Jul 31, 2026	PERMANENT PORTFOLIO FAMILY OF FUNDS, not summed
38	UBS Group AG 13F CIK 1610520 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	378,986	0.18%	+166,067	Jun 30, 2026	carried, not yet filed for the newest quarter
39	DEUTSCHE BANK AG\ 13F CIK 948046 · Non-US institution · Jun 30, 2026 carried, not yet filed for the newest quarter	331,867	0.16%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
40	NEXTBio Capital Management LP 13F CIK 2038158 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	312,496	0.15%	+179,257	Jun 30, 2026	carried, not yet filed for the newest quarter
41	Catalio Capital Management, LP 13F CIK 1958125 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	276,550	0.13%	+21,171	Jun 30, 2026	carried, not yet filed for the newest quarter
42	MARSHALL WACE, LLP 13F CIK 1318757 · Exempt reporting adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	267,592	0.13%	+198,485	Jun 30, 2026	carried, not yet filed for the newest quarter
43	HSG Holding Ltd 13F CIK 1470766 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	266,062	0.12%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
44	Focused Dynamic Growth Fund Fund S000012177 · Registered fund · Jul 31, 2026 American Century Growth Funds, Inc., not summed	263,026	0.12%	-58,236	Jul 31, 2026	American Century Growth Funds, Inc., not summed
45	FMR LLC Insider CIK 315066 · Jul 22, 2026 10% Owner, issuer-wide, not summed	261,777	0.12%	0	Jul 22, 2026	10% Owner, issuer-wide, not summed
45.1	FMR LLC 13G CIK 315066 · Holding company · Jun 30, 2026 Rule 13d-1(c), passive investor, not summed	28,197,369	13.18%	-2,915,265	Jun 30, 2026	Rule 13d-1(c), passive investor, not summed
45.2	FMR LLC 13F CIK 315066 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	7,810,306	3.65%	-593,143	Jun 30, 2026	carried, not yet filed for the newest quarter
45.3	Fidelity Advisor Growth Opportunities Fund Fund S000005111 · Registered fund · May 31, 2026 Fidelity Advisor Series I, not summed	733,500	0.34%	0	May 31, 2026	Fidelity Advisor Series I, not summed
45.4	Select Biotechnology Portfolio Fund S000007486 · Registered fund · May 31, 2026 Fidelity Select Portfolios, not summed	542,038	0.25%	-22,400	May 31, 2026	Fidelity Select Portfolios, not summed
45.5	Select Health Care Portfolio Fund S000007466 · Registered fund · May 31, 2026 Fidelity Select Portfolios, not summed	540,000	0.25%	-80,000	May 31, 2026	Fidelity Select Portfolios, not summed
46	Coll Crespo Blas Insider CIK 2037144 · Sep 21, 2026 CHIEF MEDICAL OFFICER, issuer-wide, not summed	258,228	0.12%	-22,650	Sep 21, 2026	CHIEF MEDICAL OFFICER, issuer-wide, not summed
47	Janus Henderson Venture Fund Fund S000010488 · Registered fund · Jun 30, 2026 Janus Investment Fund, not summed	252,725	0.12%	+8,726	Jun 30, 2026	Janus Investment Fund, not summed
48	SEB Asset Management AB 13F CIK 2127509 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	245,043	0.11%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
49	GOLDMAN SACHS GROUP INC 13F CIK 886982 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	242,790	0.11%	-17,753	Jun 30, 2026	carried, not yet filed for the newest quarter
49.1	Multi-Manager U.S. Small Cap Equity Fund Fund S000051363 · Registered fund · Apr 30, 2026 Goldman Sachs Trust II, not summed	6,530	0.00%	—	Apr 30, 2026	Goldman Sachs Trust II, not summed
49.2	Goldman Sachs Future Health Care Equity ETF Fund S000072296 · Registered fund · May 31, 2026 Goldman Sachs ETF Trust, not summed	1,008	0.00%	-84	May 31, 2026	Goldman Sachs ETF Trust, not summed
50	AMERIPRISE FINANCIAL INC 13F CIK 820027 · Investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	230,514	0.11%	+10,998	Jun 30, 2026	carried, not yet filed for the newest quarter
50.1	Columbia Global Opportunities Fund Fund S000031367 · Registered fund · Jul 31, 2026 Columbia Funds Series Trust II, not summed	666	0.00%	+21	Jul 31, 2026	Columbia Funds Series Trust II, not summed

40 more nested rows are not shown here; Every filing lists them all.

Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.

Showing 1–50 of 262 holders

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Key facts CIK 1888886 CUSIP 86366E106 13F (30d) 14 filings 14 filers Visit website Investor relations