Position in GPCR
as of Mar 31, 2026
· filed May 14, 2026
Position Value
$64,043,243
-$10,980,202 QoQ
Shares Held
1,328,698
+23.2% QoQ
Ownership
0.623%
of shares outstanding
% of Portfolio
1.78%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Sep 2025
3 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in GPCR Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026Siren, L.L.C. holds $3,359,319,188 across 68 Biotechnology names. GPCR ranks #18 (1.9% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | SRRK |
Scholar Rock Holding Corp
|
10,825,013 | $532,157,639 | |
| 2 | KYMR |
Kymera Therapeutics, Inc.
|
3,186,830 | $265,431,070 | |
| 3 | ERAS |
Erasca, Inc.
|
11,244,246 | $181,931,900 | |
| 4 | EWTX |
Edgewise Therapeutics, Inc.
|
4,430,263 | $139,553,284 | |
| 5 | ONC |
BeOne Medicines Ltd.
|
465,000 | $138,091,050 | |
| 6 | TNGX |
Tango Therapeutics, Inc.
|
5,657,105 | $118,346,636 | |
| 7 | BCAX |
Bicara Therapeutics Inc.
|
5,802,970 | $115,421,073 | |
| 8 | RVMD |
Revolution Medicines, Inc.
|
1,110,980 | $108,042,805 |
All Filings in GPCR
Export CSV
3 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $64,043,243 | 1,328,698 | Shares | Defined | 2026-05-14 | |
| 2025-12-31 | $75,023,445 | 1,078,698 | Shares | Defined | 2026-02-13 | |
| 2025-09-30 | $28,750,708 | 1,026,811 | Shares | Defined | 2025-11-13 | |
| No filing history on record for this holder in this stock. | ||||||