MLYS · Mineralys Therapeutics, Inc. · Holdings

$22.38 +0.29 (+1.31%) At close · Oct 8

Russell 2000 member Rebalance outlook locked

Market Cap

$1.98B

88.41M

Volume · Oct 8 2.25M Avg daily vol (3M) 1.05M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 226

Total Value: $2,761,900,421

Total Shares: 102,388,272

Showing 1–100 of 239 holdings by value · page 1 of 3

Institutional Ownership Trend

15 quarters

Holder Concentration

Across 227 13F filers

Top Holder

7.7%

of institutional value

Top 5

31.1%

of institutional value

Top 10

46.9%

of institutional value

HHI

309

Broadly held

Showing 100 of 239

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Catalys Pacific, LLC

$213,245,549

7.72%

7,903,838

RA CAPITAL MANAGEMENT, L.P.

$207,550,395

7.51%

7,692,750

BlackRock, Inc.

$158,832,278

5.75%

5,887,038

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	112,561	$3,036,895	1.9%	Sole
BlackRock Investment Management (Australia) Ltd	146	$3,939	0.0%	Sole
BlackRock Asset Management Canada Ltd	16,923	$456,582	0.3%	Sole
BlackRock Investment Management, LLC	185,815	$5,013,288	3.2%	Sole
BLACKROCK ADVISORS LLC	421,047	$11,359,848	7.2%	Sole
BlackRock Fund Advisors	2,787,107	$75,196,146	47.3%	Sole
BlackRock Institutional Trust Company, N.A.	2,110,866	$56,951,164	35.9%	Sole
BlackRock Japan Co. Ltd	1,315	$35,478	0.0%	Sole
BlackRock Fund Managers Ltd.	11,056	$298,290	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	34,674	$935,504	0.6%	Sole
BlackRock Asset Management Ireland Ltd	123,123	$3,321,858	2.1%	Sole
BlackRock (Luxembourg) S.A.	3,945	$106,436	0.1%	Sole
BlackRock Asset Management Schweiz AG	10,291	$277,651	0.2%	Sole
Aperio Group, LLC	68,169	$1,839,199	1.2%	Sole

SAMSARA BIOCAPITAL, LLC

$158,400,065

5.74%

5,871,018

FMR LLC

$121,725,368

4.41%

4,511,689

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	3,780,413	$101,995,542	83.8%	Defined
STRATEGIC ADVISERS LLC	230	$6,205	0.0%	Defined
FIAM LLC	731,046	$19,723,621	16.2%	Defined

STATE STREET CORP

$111,741,339

4.05%

4,141,636

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	4,141,636	$111,741,339	100.0%	Defined

DEERFIELD MANAGEMENT COMPANY, L.P.

$106,786,840

3.87%

3,958,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deerfield UGP, LLC	3,958,000	$106,786,840	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$74,377,654

2.69%

2,756,770

Laurion Capital Management LP

$67,615,980

2.45%

2,506,152

PRICE T ROWE ASSOCIATES INC /MD/

$61,041,601

2.21%

2,262,476

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	84,056	$2,267,830	3.7%	Defined
Held directly	2,178,420	$58,773,771	96.3%	Sole

ORBIMED ADVISORS LLC

$56,935,894

2.06%

2,110,300

Capital World Investors

$53,895,436

1.95%

1,997,607

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	1,997,607	$53,895,436	100.0%	Defined

ARMISTICE CAPITAL, LLC

$46,837,280

1.70%

1,736,000

Troluce Capital Advisors LLC

$46,641,755

1.69%

1,728,753

FRANKLIN RESOURCES INC

$44,126,328

1.60%

1,635,520

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST CO INTERNATIONAL	109	$2,940	0.0%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	892	$24,066	0.1%	Defined
FRANKLIN ADVISERS INC	1,632,278	$44,038,860	99.8%	Defined
PUTNAM ADVISORY CO LLC	2,241	$60,462	0.1%	Defined

ANDERA PARTNERS

$42,949,920

1.56%

1,591,917

GEODE CAPITAL MANAGEMENT, LLC

$42,745,114

1.55%

1,584,326

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	225,951	$6,096,157	14.3%	Defined
Held directly	1,358,375	$36,648,957	85.7%	Defined

SR One Capital Management, LP

$42,195,802

1.53%

1,563,966

BANK OF AMERICA CORP /DE/

$40,619,656

1.47%

1,505,547

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	1,347,868	$36,365,478	89.5%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	61,943	$1,671,222	4.1%	Defined
BOFA SECURITIES, INC.	87,628	$2,364,203	5.8%	Defined
MANAGED ACCOUNT ADVISORS LLC	8,108	$218,753	0.5%	Defined

SPHERA FUNDS MANAGEMENT LTD.

$39,659,817

1.44%

1,469,971

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	1,469,971	$39,659,817	100.0%	Defined

GOLDMAN SACHS GROUP INC

$39,355,077

1.42%

1,458,676

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	1,146,220	$30,925,015	78.6%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	312,456	$8,430,062	21.4%	Defined

Pictet Asset Management Holding SA

$38,598,910

1.40%

1,430,649

Polar Capital Holdings Plc

$38,334,640

1.39%

1,420,854

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	1,420,854	$38,334,640	100.0%	Defined

MILLENNIUM MANAGEMENT LLC

$32,963,030

1.19%

1,221,758

Ghisallo Capital Management LLC

$30,352,500

1.10%

1,125,000

Invesco Ltd.

$29,440,033

1.07%

1,091,180

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	1,056,301	$28,498,998	96.8%	Defined
Invesco Trust Co joint	22,731	$613,282	2.1%	Defined
Invesco Capital Management LLC	12,148	$327,753	1.1%	Defined

ALLIANCEBERNSTEIN L.P.

$28,802,256

1.04%

1,067,541

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	1,067,541	$28,802,256	100.0%	Defined

Logos Global Management LP

$28,329,000

1.03%

1,050,000

ARMISTICE CAPITAL, LLC

$28,059,200

1.02%

1,040,000

AMERICAN CENTURY COMPANIES INC

$27,971,973

1.01%

1,036,767

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	1,036,767	$27,971,973	100.0%	Defined

MORGAN STANLEY

$24,746,403

0.90%

917,213

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	20	$539	0.0%	Defined
MORGAN STANLEY & CO. LLC	24,479	$660,443	2.7%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	537,735	$14,508,090	58.6%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	3,094	$83,476	0.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	15,569	$420,050	1.7%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	336,316	$9,073,805	36.7%	Defined

Davern Capital Partners, LP

$23,169,155

0.84%

858,753

Candriam S.C.A.

$23,122,858

0.84%

857,037

Caption Management, LLC

$22,976,168

0.83%

851,600

Nantahala Capital Management, LLC

$22,136,577

0.80%

820,481

WELLINGTON MANAGEMENT GROUP LLP

$21,765,194

0.79%

806,716

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	462,124	$12,468,105	57.3%	Defined
Wellington Managment Canada LLC	21,369	$576,535	2.6%	Defined
Wellington Management Singapore Pte. Ltd.	29,581	$798,095	3.7%	Defined
Wellington Management International Ltd	26,368	$711,408	3.3%	Defined
Wellington Trust Company, NA joint	256,823	$6,929,084	31.8%	Defined
Wellington Management Australia Pty Ltd	9,072	$244,762	1.1%	Defined
Wellington Management Europe GmbH	1,379	$37,205	0.2%	Defined

Affinity Asset Advisors, LLC

$20,235,000

0.73%

750,000

VANGUARD PORTFOLIO MANAGEMENT LLC

$20,171,785

0.73%

747,657

TUDOR INVESTMENT CORP ET AL

$19,921,222

0.72%

738,370

Aberdeen Group plc

$18,595,560

0.67%

689,235

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	689,235	$18,595,560	100.0%	Defined

ALGERT GLOBAL LLC

$17,510,748

0.63%

649,027

Catalio Capital Management, LP

$17,502,519

0.63%

648,722

Pale Fire Capital SE

$16,573,382

0.60%

614,284

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Barta Jan joint	614,284	$16,573,382	100.0%	Defined

STEMPOINT CAPITAL LP

$16,260,468

0.59%

602,686

NORTHERN TRUST CORP

$14,879,225

0.54%

551,491

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	510,052	$13,761,202	92.5%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	32,421	$874,718	5.9%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	9,018	$243,305	1.6%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$14,062,407

0.51%

521,216

Rock Springs Capital Management LP

$13,083,977

0.47%

484,951

CITADEL ADVISORS LLC

$12,615,793

0.46%

467,598

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	380,513	$10,266,240	81.4%	Defined
Held directly	87,085	$2,349,553	18.6%	Defined

DIMENSIONAL FUND ADVISORS LP

$12,502,180

0.45%

463,387

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	3,388	$91,408	0.7%	Defined
Dimensional Fund Advisors Pte. Ltd.	512	$13,813	0.1%	Defined
Dimensional Ireland Ltd	8,691	$234,483	1.9%	Defined
Held directly	450,796	$12,162,476	97.3%	Sole

VANGUARD FIDUCIARY TRUST CO

$12,150,982

0.44%

450,370

Integral Health Asset Management, LLC

$12,141,000

0.44%

450,000

Prosight Management, LP

$12,135,469

0.44%

449,795

Rhenman & Partners Asset Management AB

$11,233,689

0.41%

416,371

Caption Management, LLC

$11,145,087

0.40%

413,087

JENNISON ASSOCIATES LLC

$10,326,514

0.37%

382,747

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	382,747	$10,326,514	100.0%	Defined

Parkman Healthcare Partners LLC

$10,261,950

0.37%

380,354

RENAISSANCE TECHNOLOGIES LLC

$10,206,534

0.37%

378,300

CenterBook Partners LP

$9,864,697

0.36%

365,630

UBS Group AG

$9,755,858

0.35%

361,596

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	156	$4,208	0.0%	Defined
UBS AG	357,181	$9,636,743	98.8%	Defined
UBS Switzerland AG	4,259	$114,907	1.2%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$9,593,278

0.35%

355,570

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	355,570	$9,593,278	100.0%	Other

D. E. Shaw & Co., Inc.

$9,516,627

0.34%

352,729

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	295,128	$7,962,553	83.7%	Defined
D. E. Shaw Investment Management, L.L.C. joint	57,601	$1,554,074	16.3%	Defined

Eversept Partners, LP

$8,355,409

0.30%

309,689

SCHRODER INVESTMENT MANAGEMENT GROUP

$8,288,633

0.30%

307,214

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	306,972	$8,282,104	99.9%	Sole
Schroder Investment Management North America Inc.	242	$6,529	0.1%	Sole

ADAR1 Capital Management, LLC

$8,063,944

0.29%

298,886

Longaeva Partners L.P.

$7,584,185

0.27%

281,104

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Balyasny Asset Management L.P.	281,104	$7,584,185	100.0%	Other

Nuveen, LLC

$7,415,262

0.27%

274,843

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	4,761	$128,451	1.7%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	143,720	$3,877,565	52.3%	Defined
TEACHERS ADVISORS, LLC joint	126,362	$3,409,246	46.0%	Defined

Qube Research & Technologies Ltd

$6,738,956

0.24%

249,776

TimesSquare Capital Management, LLC

$6,363,448

0.23%

235,858

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GuideStone Capital Management, LLC joint	235,858	$6,363,448	100.0%	Sole

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$4,818,628

0.17%

178,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	178,600	$4,818,628	100.0%	Other

SUVRETTA CAPITAL MANAGEMENT, LLC

$4,691,444

0.17%

173,886

Trexquant Investment LP

$4,578,910

0.17%

169,715

TWO SIGMA INVESTMENTS, LP

$4,372,972

0.16%

162,082

Bank of New York Mellon Corp

$4,277,676

0.15%

158,550

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation joint	51,897	$1,400,180	32.7%	Defined
The Bank of New York Mellon	106,526	$2,874,071	67.2%	Defined
BNY Mellon, NA joint	126	$3,399	0.1%	Defined
Held directly	1	$26	0.0%	Defined

Brevan Howard Capital Management LP

$4,147,419

0.15%

153,722

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Brevan Howard Investment Products Ltd	153,722	$4,147,419	100.0%	Defined

AQR CAPITAL MANAGEMENT LLC

$4,114,555

0.15%

152,504

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	4	$107	0.0%	Other
Arax Advisory Partners	96	$2,590	0.1%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	378	$10,198	0.2%	Other
Stokes Family Office, LLC	125	$3,372	0.1%	Other
Held directly	151,901	$4,098,288	99.6%	Defined

Burkehill Global Management, LP

$4,047,000

0.15%

150,000

BOOTHBAY FUND MANAGEMENT, LLC

$3,976,905

0.14%

147,402

Caption Management, LLC

$3,879,724

0.14%

143,800

Artia Global Partners LP

$3,717,844

0.13%

137,800

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$3,609,924

0.13%

133,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	133,800	$3,609,924	100.0%	Other

Russell Investments Group, Ltd.

$3,460,101

0.13%

128,247

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	51,516	$1,389,901	40.2%	Defined
Russell Investments Capital, LLC	64,408	$1,737,727	50.2%	Defined
Russell Investments France SAS	4,110	$110,887	3.2%	Defined
Russell Investments Trust Company	8,213	$221,586	6.4%	Defined

VOYA INVESTMENT MANAGEMENT LLC

$3,399,236

0.12%

125,991

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	125,991	$3,399,236	100.0%	Defined

Ensign Peak Advisors, Inc

$3,193,946

0.12%

118,382

22NW, LP

$3,071,403

0.11%

113,840

Swiss National Bank

$3,010,968

0.11%

111,600

Ishara Investments LP

$2,765,450

0.10%

102,500

MARK ASSET MANAGEMENT LP

$2,732,777

0.10%

101,289

ExodusPoint Capital Management, LP

$2,726,382

0.10%

101,052

Timothy G. Youngquist 2020 Irrevocable Trust

$2,721,445

0.10%

100,869

CITIGROUP INC

$2,679,976

0.10%

99,332

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	99,332	$2,679,976	100.0%	Defined

Schonfeld Strategic Advisors LLC

$2,569,629

0.09%

95,242

ALPS ADVISORS INC

$2,400,572

0.09%

88,976

Squarepoint Ops LLC

$2,329,102

0.08%

86,327

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	86,327	$2,329,102	100.0%	Defined

HighVista Strategies LLC

$2,322,573

0.08%

86,085

BlueCrest Capital Management Ltd

$2,297,535

0.08%

85,157

KVP Capital Advisors, LP

$2,270,852

0.08%

84,168

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$2,136,787

0.08%

79,199

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	1,142	$30,811	1.4%	Defined
UBS Asset Management Switzerland AG	66,106	$1,783,539	83.5%	Defined
Held directly	11,951	$322,437	15.1%	Defined

Rafferty Asset Management, LLC

$2,109,458

0.08%

78,186

CITADEL ADVISORS LLC

$2,045,084

0.07%

75,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	75,800	$2,045,084	100.0%	Defined

STATE OF WISCONSIN INVESTMENT BOARD

$1,976,689

0.07%

73,265

Key facts CIK 1933414 CUSIP 603170101 13F (30d) 6 filings 6 filers Visit website Investor relations