Jefferies Financial Group Inc.
Position in GPCR — Structure Therapeutics Inc.
CIK 96223
NEW YORK, NY
Position in GPCR
as of Mar 31, 2026
· filed May 8, 2026
Position Value
$3,016,934
-$4,146,229 QoQ
Shares Held
62,592
-39.2% QoQ
Ownership
0.029%
of shares outstanding
% of Portfolio
0.05%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2024
6 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in GPCR Over Time
Shares Held
Position Value (USD)
Derivatives in GPCR
reported options exposure · as of Dec 31, 2024CallValue
$734,952
CallShares
27,100
PutValue
$0
PutShares
0
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026Jefferies Financial Group Inc. holds $507,430,268 across 85 Biotechnology names. GPCR ranks #30 (0.6% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | PTCT |
Ptc Therapeutics, Inc.
|
1,354,459 | $92,279,291 | |
| 2 | IMTX |
Immatics N.V.
|
5,059,551 | $49,785,981 | |
| 3 | URGN |
UroGen Pharma Ltd.
|
2,199,652 | $39,549,742 | |
| 4 | JAZZ |
Jazz Pharmaceuticals plc
|
175,599 | $33,196,990 | |
| 5 | BMRN |
Biomarin Pharmaceutical Inc
|
468,146 | $26,445,567 | |
| 6 | IMNM |
Immunome Inc.
|
1,160,715 | $25,384,837 | |
| 7 | ARGX |
Argenx SE
|
30,005 | $21,911,151 | |
| 8 | DNTH |
Dianthus Therapeutics, Inc. /DE/
|
202,410 | $16,986,247 |
All Filings in GPCR
Export CSV
9 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $3,016,934 | 62,592 | Shares | Defined | 2026-05-08 | |
| 2025-12-31 | $7,163,163 | 102,993 | Shares | Defined | 2026-02-09 | |
| 2025-09-30 | $4,769,660 | 170,345 | Shares | Defined | 2025-11-13 | |
| 2024-12-31 | $54,240 | 2,000 | Shares | Defined | 2025-02-27 | |
| 2024-12-31 | $734,952 | 27,100 | Call | Defined | 2025-02-27 | |
| 2024-09-30 | $307,230 | 7,000 | Shares | Defined | 2024-11-14 | |
| 2024-09-30 | $1,189,419 | 27,100 | Call | Defined | 2024-11-14 | |
| 2024-03-31 | $85,720 | 2,000 | Shares | Defined | 2024-05-13 | |
| 2024-03-31 | $2,010,134 | 46,900 | Call | Defined | 2024-05-13 | |
| No filing history on record for this holder in this stock. | ||||||