PRINCIPAL FINANCIAL GROUP INC

Position in GPCR — Structure Therapeutics Inc.

CIK 1126328 DES MOINES, IA

Position in GPCR

as of Jun 30, 2026 · filed Aug 4, 2026 Compact

Position Value

$94,070,253

+$9,538,829 QoQ

Shares Held

1,752,753

-0.1% QoQ

Ownership

2.46%

of shares outstanding

% of Portfolio

0.05%

of 13F equity value

Holder Rank

of 191 holders

Holding Since

Jun 2024

9 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

PRINCIPAL FINANCIAL GROUP INC holds $1,852,088,599 across 105 Biotechnology names. GPCR ranks #4 (5.1% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ASND	Ascendis Pharma A/S	873,502	$232,980,453
2	VRTX	Vertex Pharmaceuticals Inc / Ma	389,511	$193,481,798
3	CYTK	Cytokinetics Inc	1,311,664	$111,740,655
4	GPCR	Structure Therapeutics Inc. This page	1,752,753	$94,070,253
5	INSM	INSMED Inc	856,126	$91,280,154
6	AXSM	Axsome Therapeutics, Inc.	332,642	$81,420,782
7	BBIO	BridgeBio Pharma, Inc.	1,024,423	$76,299,024
8	REGN	Regeneron Pharmaceuticals, Inc.	121,053	$75,481,386

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$94,070,253	1,752,753	-0.1%	Shares	Defined	2026-08-04
2026-03-31	$84,531,424	1,753,764	+36.6%	Shares	Defined	2026-05-04
2025-12-31	$89,316,805	1,284,210	+63.1%	Shares	Defined	2026-02-02
2025-09-30	$22,049,552	787,484	-7.7%	Shares	Defined	2025-11-04
2025-06-30	$17,695,409	853,202	+12.8%	Shares	Defined	2025-08-08
2025-03-31	$13,098,598	756,707	-4.4%	Shares	Defined	2025-04-28
2024-12-31	$21,455,553	791,134	+45.1%	Shares	Defined	2025-01-31
2024-09-30	$23,935,806	545,359	+230.0%	Shares	Defined	2024-12-19
2024-06-30	$6,489,131	165,244	—	Shares	Defined	2024-07-29
No filing history on record for this holder in this stock.