QURE · uniQure N.V.

$44.50 -0.36 (-0.80%) At close · Sep 4

Market Cap

$2.83B

63.07M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Quarter:

Holders: 260

Total Value: $3,558,264,974

Total Shares: 77,252,825

Showing 1–100 of 300 holdings by value · page 1 of 3

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 260 13F filers · Δ vs Mar 31, 2026

Top Holder

8.7%

+0.9 pts

Top 5

28.4%

+1.3 pts

Top 10

43.1%

−1.0 pts

HHI

282

Broadly held−2

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +38

Institutional value: +186.4%

Shares held: +1.7%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega JPMORGAN CHASE & CO	+2,030,289	4,867,755
Large RTW INVESTMENTS, LP	+1,355,216	3,941,572
Mega JANE STREET GROUP, LLC	+1,194,288	2,249,683
Mid Boxer Capital Management, LLC	+841,300	1,503,300
Small MAK CAPITAL ONE LLC	+790,846	1,232,051

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large Aberdeen Group plc	−2,458,269	2,848,117
Mega CITIGROUP INC	−1,997,541	813,944
Mid Nantahala Capital Management, LLC	−1,419,918	1,417,160
Mega TWO SIGMA INVESTMENTS, LP	−1,213,847	1,462,024
Mid 683 Capital Management, LLC	−862,400	891,200

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mid Longaeva Partners L.P.	804,594	$37,059,599
Mega Invesco Ltd.	627,823	$28,917,525
Large Point72 Asset Management, L.P.	606,212	$27,922,124
Mid Kinetic Partners Management, LP	581,000	$26,760,860
Mid GILDER GAGNON HOWE & CO LLC	530,979	$24,456,892

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mid Siren, L.L.C.	1,000,000	$16,350,000
Small Whitefort Capital Management, LP	657,611	$10,751,939
Small Catalio Capital Management, LP	491,116	$8,029,746
Large ExodusPoint Capital Management, LP	436,467	$7,136,235
Small Ally Bridge Group (NY) LLC	300,000	$4,905,000

Filter: New 89 Increased 86 Reduced 67 Sold out 51 Unchanged 18

Showing 100 of 300

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Avoro Capital Advisors LLC

$309,881,408

8.71%

6,727,777

JPMORGAN CHASE & CO

$224,208,791

6.30%

4,867,755

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	137,253	$6,321,873	2.8%	Defined
J.P. Morgan Investment Management Inc.	4,103,570	$189,010,433	84.3%	Other
J.P. Morgan Securities LLC	65	$2,993	0.0%	Defined
J.P. Morgan Securities plc	4,294	$197,781	0.1%	Defined
JPMorgan Asset Management (UK) Ltd	515,940	$23,764,196	10.6%	Defined
JPMorgan Asset Management (Asia Pacific) Ltd	11,121	$512,233	0.2%	Defined
JPMorgan Asset Management (Japan) Ltd	95,512	$4,399,282	2.0%	Defined

RTW INVESTMENTS, LP

$181,548,806

5.10%

3,941,572

STATE STREET CORP

$133,750,179

3.76%

2,903,825

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	2,903,825	$133,750,179	100.0%	Defined

Aberdeen Group plc

$131,184,269

3.69%

2,848,117

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	2,848,117	$131,184,269	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$118,728,862

3.34%

2,577,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	2,577,700	$118,728,862	100.0%	Other

BlackRock, Inc.

$86,475,481

2.43%

1,877,453

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	14,067	$647,926	0.7%	Sole
BlackRock Investment Management, LLC	38	$1,750	0.0%	Sole
BlackRock Fund Advisors	531,939	$24,501,110	28.3%	Sole
BlackRock Institutional Trust Company, N.A.	1,118,707	$51,527,644	59.6%	Sole
BlackRock Fund Managers Ltd.	8,963	$412,835	0.5%	Sole
BlackRock Investment Management (UK) Ltd.	18,856	$868,507	1.0%	Sole
BlackRock Asset Management Ireland Ltd	139,366	$6,419,197	7.4%	Sole
BlackRock Asset Management Schweiz AG	8,246	$379,810	0.4%	Sole
Aperio Group, LLC	37,271	$1,716,702	2.0%	Sole

ORBIMED ADVISORS LLC

$83,252,805

2.34%

1,807,486

Caption Management, LLC

$74,967,256

2.11%

1,627,600

JANE STREET GROUP, LLC

$74,178,846

2.08%

1,610,483

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	1,263,488	$58,196,257	78.5%	Defined
Jane Street Global Trading, LLC	346,995	$15,982,589	21.5%	Defined

JENNISON ASSOCIATES LLC

$71,918,635

2.02%

1,561,412

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	1,512,815	$69,680,258	96.9%	Defined
Prudential Trust Company	48,597	$2,238,377	3.1%	Other

Boxer Capital Management, LLC

$69,241,998

1.95%

1,503,300

GOLDMAN SACHS GROUP INC

$67,982,533

1.91%

1,475,956

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	1,467,100	$67,574,626	99.4%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	8,856	$407,907	0.6%	Defined

TWO SIGMA INVESTMENTS, LP

$67,340,825

1.89%

1,462,024

Two Seas Capital LP

$66,391,344

1.87%

1,441,410

FMR LLC

$58,499,331

1.64%

1,270,068

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	1,183,127	$54,494,829	93.2%	Defined
FIDELITY MANAGEMENT TRUST CO	80,800	$3,721,648	6.4%	Defined
STRATEGIC ADVISERS LLC	141	$6,494	0.0%	Defined
FIAM LLC	6,000	$276,360	0.5%	Defined

MAK CAPITAL ONE LLC

$56,748,269

1.59%

1,232,051

MPM BIOIMPACT LLC

$56,462,881

1.59%

1,225,855

MORGAN STANLEY

$49,129,389

1.38%

1,066,639

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	104	$4,790	0.0%	Defined
MORGAN STANLEY & CO. LLC	4,889	$225,187	0.5%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	722,322	$33,270,151	67.7%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	241,880	$11,140,992	22.7%	Defined
MORGAN STANLEY SMITH BARNEY LLC	16,143	$743,546	1.5%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	81,301	$3,744,723	7.6%	Defined

CITADEL ADVISORS LLC

$46,069,212

1.29%

1,000,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	1,000,200	$46,069,212	100.0%	Defined

Vestal Point Capital, LP

$43,066,100

1.21%

935,000

MAVERICK CAPITAL LTD

$42,623,140

1.20%

925,383

CITADEL ADVISORS LLC

$41,930,168

1.18%

910,338

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	470,137	$21,654,510	51.6%	Defined
Held directly	440,201	$20,275,658	48.4%	Defined

Fiera Capital Corp

$41,875,034

1.18%

909,141

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fiera Capital Inc.	773,524	$35,628,515	85.1%	Other
Held directly	135,617	$6,246,519	14.9%	Sole

Integral Health Asset Management, LLC

$41,454,000

1.17%

900,000

GEODE CAPITAL MANAGEMENT, LLC

$39,640,663

1.11%

860,631

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	152,821	$7,038,935	17.8%	Defined
Held directly	707,810	$32,601,728	82.2%	Defined

Longaeva Partners L.P.

$37,059,599

1.04%

804,594

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Balyasny Asset Management L.P.	804,594	$37,059,599	100.0%	Other

Nantahala Capital Management, LLC

$36,848,000

1.04%

800,000

VANGUARD CAPITAL MANAGEMENT LLC

$35,916,620

1.01%

779,779

CITIGROUP INC

$30,629,900

0.86%

665,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	665,000	$30,629,900	100.0%	Defined

Invesco Ltd.

$28,917,525

0.81%

627,823

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	535,119	$24,647,579	85.2%	Defined
Invesco Capital Management LLC	92,704	$4,269,946	14.8%	Defined

First Turn Management, LLC

$28,047,085

0.79%

608,925

Point72 Asset Management, L.P.

$27,922,124

0.78%

606,212

CITADEL ADVISORS LLC

$27,484,002

0.77%

596,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	596,700	$27,484,002	100.0%	Defined

Balyasny Asset Management L.P.

$27,017,966

0.76%

586,582

Kinetic Partners Management, LP

$26,760,860

0.75%

581,000

BANK OF AMERICA CORP /DE/

$26,658,880

0.75%

578,786

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	203,796	$9,386,843	35.2%	Defined
BOFA SECURITIES, INC.	116,046	$5,345,078	20.0%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	258,944	$11,926,959	44.7%	Defined

683 Capital Management, LLC

$26,484,500

0.74%

575,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
683 Capital Partners, LP	575,000	$26,484,500	100.0%	Defined

TUDOR INVESTMENT CORP ET AL

$25,254,698

0.71%

548,300

JANE STREET GROUP, LLC

$25,231,668

0.71%

547,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	547,800	$25,231,668	100.0%	Defined

GILDER GAGNON HOWE & CO LLC

$24,456,892

0.69%

530,979

Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.

$24,028,442

0.68%

521,677

Assenagon Asset Management S.A.

$23,653,191

0.66%

513,530

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$22,887,075

0.64%

496,897

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	496,897	$22,887,075	100.0%	Other

UBS Group AG

$21,536,318

0.61%

467,571

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	132,662	$6,110,411	28.4%	Defined
UBS AG	284,730	$13,114,663	60.9%	Defined
UBS Switzerland AG	50,179	$2,311,244	10.7%	Defined

Nantahala Capital Management, LLC

$20,987,699

0.59%

455,660

Voss Capital, LP

$20,743,627

0.58%

450,361

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$19,349,806

0.54%

420,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	420,100	$19,349,806	100.0%	Other

Rubric Capital Management LP

$18,819,240

0.53%

408,581

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$18,577,748

0.52%

403,338

READYSTATE ASSET MANAGEMENT LP

$18,469,553

0.52%

400,989

VANGUARD FIDUCIARY TRUST CO

$17,024,098

0.48%

369,607

MILLENNIUM MANAGEMENT LLC

$15,804,383

0.44%

343,126

Creek Drive Management Group LLC

$15,522,220

0.44%

337,000

TUDOR INVESTMENT CORP ET AL

$15,148,627

0.43%

328,889

Privium Fund Management B.V.

$15,122,511

0.42%

328,322

ADAR1 Capital Management, LLC

$14,954,392

0.42%

324,672

683 Capital Management, LLC

$14,564,172

0.41%

316,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
683 Capital Partners, LP	316,200	$14,564,172	100.0%	Defined

MARSHALL WACE, LLP

$14,034,573

0.39%

304,702

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	304,702	$14,034,573	100.0%	Other

BRAIDWELL LP

$13,894,091

0.39%

301,652

DIADEMA PARTNERS LP

$13,771,940

0.39%

299,000

Squarepoint Ops LLC

$12,910,618

0.36%

280,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	280,300	$12,910,618	100.0%	Defined

FRANKLIN RESOURCES INC

$11,297,227

0.32%

245,272

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST INTERNATIONAL LLC	274	$12,620	0.1%	Defined
FRANKLIN ADVISERS INC	244,998	$11,284,607	99.9%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$11,249,602

0.32%

244,238

DIADEMA PARTNERS LP

$10,842,524

0.30%

235,400

FourWorld Capital Management LLC

$10,133,200

0.28%

220,000

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$10,018,050

0.28%

217,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	217,500	$10,018,050	100.0%	Defined

NORTHERN TRUST CORP

$9,807,784

0.28%

212,935

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	189,065	$8,708,333	88.8%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	23,870	$1,099,451	11.2%	Defined

Parkman Healthcare Partners LLC

$9,588,310

0.27%

208,170

D. E. Shaw & Co., Inc.

$9,563,391

0.27%

207,629

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	207,629	$9,563,391	100.0%	Defined

TUDOR INVESTMENT CORP ET AL

$9,396,240

0.26%

204,000

Caption Management, LLC

$9,262,666

0.26%

201,100

Affinity Asset Advisors, LLC

$9,212,000

0.26%

200,000

MILLENNIUM MANAGEMENT LLC

$9,202,788

0.26%

199,800

Diametric Capital, LP

$9,084,966

0.26%

197,242

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Thakore Nainoor	197,242	$9,084,966	100.0%	Defined

BARCLAYS PLC

$8,686,916

0.24%

188,600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS CAPITAL INC.	188,600	$8,686,916	100.0%	Defined

PICTON MAHONEY ASSET MANAGEMENT

$8,346,762

0.23%

181,215

Affinity Asset Advisors, LLC

$8,060,500

0.23%

175,000

Trexquant Investment LP

$7,883,122

0.22%

171,149

PERCEPTIVE ADVISORS LLC

$7,738,080

0.22%

168,000

Freshford Capital Management, LLC

$7,455,040

0.21%

161,855

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FRESHFORD PARTNERS, LP	70,007	$3,224,522	43.3%	Sole
Long Meadow, L.P.	71,269	$3,282,650	44.0%	Sole
Held directly	20,579	$947,868	12.7%	Sole

Nantahala Capital Management, LLC

$7,438,690

0.21%

161,500

FLAX POND CAPITAL, LLC

$7,218,799

0.20%

156,726

AMERIPRISE FINANCIAL INC

$7,016,917

0.20%

152,343

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	152,022	$7,002,133	99.8%	Defined
Ameriprise Financial Services, LLC	79	$3,638	0.1%	Defined
Ameriprise Bank, FSB	242	$11,146	0.2%	Defined

LMR Partners LLP

$6,909,000

0.19%

150,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wabon Partners, L.P.	150,000	$6,909,000	100.0%	Sole

Casdin Capital, LLC

$6,909,000

0.19%

150,000

WELLS FARGO & COMPANY/MN

$6,907,663

0.19%

149,971

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	39,072	$1,799,656	26.1%	Defined
WELLS FARGO CLEARING SERVICES, LLC	110,899	$5,108,007	73.9%	Defined

Hennion & Walsh Asset Management, Inc.

$6,545,724

0.18%

142,113

VANGUARD PORTFOLIO MANAGEMENT LLC

$6,498,743

0.18%

141,093

HRT FINANCIAL LP

$6,247,624

0.18%

135,641

CITIGROUP INC

$5,893,100

0.17%

127,944

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	127,944	$5,893,100	100.0%	Defined

SIG BROKERAGE, LP

$5,872,650

0.17%

127,500

ENVESTNET ASSET MANAGEMENT INC

$5,830,090

0.16%

126,576

ROYAL BANK OF CANADA

$5,724,933

0.16%

124,293

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Capital Markets, LLC	123,838	$5,703,978	99.6%	Defined
RBC Dominion Securities Inc.	148	$6,816	0.1%	Defined
RBC Trust Co (Delaware) Ltd	118	$5,435	0.1%	Defined
RBC Rochdale, LLC	98	$4,513	0.1%	Defined
Held directly	91	$4,191	0.1%	Sole

Susquehanna Portfolio Strategies, LLC

$5,613,286

0.16%

121,869

Hudson Bay Capital Management LP

$5,527,200

0.16%

120,000

NAN FUNG TRINITY (HK) LTD

$5,319,653

0.15%

115,494

SIMPLEX TRADING, LLC

$5,076,687

0.14%

110,219

SILVERARC CAPITAL MANAGEMENT, LLC

$4,836,300

0.14%

105,000

Ghisallo Capital Management LLC

$4,606,000

0.13%

100,000

Key facts CIK 1590560 CUSIP N90064101 13F (30d) 211 filings 209 filers Visit website Investor relations