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Opus Genetics, Inc.
$4.23 +0.05 (+1.20%) At close · Jul 2
Market Cap
$344.30M
Shares
81,395,539

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 80
Total Value: $262,271,677
Total Shares: 57,642,134

Institutional Ownership Trend

22 quarters

Holder Concentration

Across 79 13F filers · Δ vs Dec 31, 2025
Top Holder
13.3%
Jun 2023 → Mar 2026 · range 13.3% – 39.0%
−3.8 pts
Top 5
46.4%
Jun 2023 → Mar 2026 · range 46.4% – 78.6%
−17.6 pts
Top 10
69.9%
Jun 2023 → Mar 2026 · range 69.9% – 94.5%
−17.9 pts
HHI
654
Jun 2023 → Mar 2026 · range 654 – 1,803
Broadly held−357

Quarterly Activity

vs Dec 31, 2025
New
29
Increased
16
Decreased
15
Sold Out
8
Unchanged
20
Holder count: +21
Institutional value: +368.4%
Shares held: +106.9%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Large ADAGE CAPITAL PARTNERS GP, L.L.C. +4,924,779 6,029,775
Large MARSHALL WACE, LLP +2,155,732 2,313,380
Mid ADAR1 Capital Management, LLC +1,809,004 1,849,004
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP +656,948 904,783
Mega MILLENNIUM MANAGEMENT LLC +627,882 2,630,432

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid Nantahala Capital Management, LLC −3,100,000 1,681,330
Mid PERCEPTIVE ADVISORS LLC −2,489,158 1,835,842
Small Mink Brook Asset Management LLC −1,075,079 590,552
Mega WELLS FARGO & COMPANY/MN −238,086 3,785
Mega CITADEL ADVISORS LLC −59,821 120,900

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mid Caligan Partners LP 12,150,056 $55,282,754
— Adage Capital Management, L.P. 6,029,775 $27,435,476
Mega VANGUARD CAPITAL MANAGEMENT LLC 2,449,987 $11,147,440
Small Boxer Capital Management, LLC 2,250,000 $10,237,500
Large Woodline Partners LP 1,354,030 $6,160,836

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 2,322,897 $4,669,022
Mid Voss Capital, LP 441,891 $888,200
Large Qube Research & Technologies Ltd 39,978 $80,355
Mid JOHNSON INVESTMENT COUNSEL INC 20,000 $40,200
Mid Virtu Financial LLC 16,810 $33,788
Filter: New 29 Increased 16 Reduced 15 Sold out 8 Unchanged 20
Showing 83 of 83
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mid Caligan Partners LP $27,641,377 10.54% 6,075,028
Mid Caligan Partners LP $27,641,377 10.54% 6,075,028
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $27,435,476 10.46% 6,029,775
— Adage Capital Management, L.P. $27,435,476 10.46% 6,029,775
Micro BIOS Capital Management, LP $16,759,601 6.39% 3,683,429
Large Balyasny Asset Management L.P. $12,367,031 4.72% 2,718,029
Mega MILLENNIUM MANAGEMENT LLC $11,968,465 4.56% 2,630,432
Mega VANGUARD CAPITAL MANAGEMENT LLC $11,147,440 4.25% 2,449,987
Large MARSHALL WACE, LLP $10,525,878 4.01% 2,313,380
Small Boxer Capital Management, LLC $10,237,500 3.90% 2,250,000
Mid ADAR1 Capital Management, LLC $8,412,968 3.21% 1,849,004
Mid PERCEPTIVE ADVISORS LLC $8,353,081 3.18% 1,835,842
Mid Nantahala Capital Management, LLC $7,650,051 2.92% 1,681,330
Large Woodline Partners LP $6,160,836 2.35% 1,354,030
Mid BOOTHBAY FUND MANAGEMENT, LLC $5,410,464 2.06% 1,189,113
Small Opaleye Management Inc. $5,096,000 1.94% 1,120,000
Large FARALLON CAPITAL MANAGEMENT LLC $4,550,000 1.73% 1,000,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,746,392 1.43% 823,383
Small Bleichroeder LP $3,352,631 1.28% 736,842
Small Mink Brook Asset Management LLC $2,687,011 1.02% 590,552
Mega GEODE CAPITAL MANAGEMENT, LLC $2,449,478 0.93% 538,347
Small Trails Edge Capital Partners, LP $2,275,000 0.87% 500,000
Mega AMERIPRISE FINANCIAL INC $1,767,633 0.67% 388,491
Mega GOLDMAN SACHS GROUP INC $1,486,980 0.57% 326,809
Small GREAT POINT PARTNERS LLC $1,475,747 0.56% 324,340
Mega VANGUARD FIDUCIARY TRUST CO Bank $1,282,194 0.49% 281,801
Mega UBS Group AG $1,172,302 0.45% 257,649
Mega STATE STREET CORP $909,786 0.35% 199,953
Mega JANE STREET GROUP, LLC $719,368 0.27% 158,103
Mega BlackRock, Inc. $672,216 0.26% 147,740
Mid Voleon Capital Management LP $654,271 0.25% 143,796
Small Seven Fleet Capital Management LP $610,801 0.23% 134,242
Large Creative Planning $584,065 0.22% 128,366
Mega CITADEL ADVISORS LLC $550,095 0.21% 120,900
Mega TWO SIGMA INVESTMENTS, LP $494,316 0.19% 108,641
Mega NORTHERN TRUST CORP Bank $429,588 0.16% 94,415
Small Texas Capital Bank Wealth Management Services Inc Bank $402,675 0.15% 88,500
Mid SIMPLEX TRADING, LLC $375,284 0.14% 82,480
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $370,370 0.14% 81,400
Large RENAISSANCE TECHNOLOGIES LLC $333,100 0.13% 73,209
Small Stonepine Capital Management, LLC $312,530 0.12% 68,688
Small Regency Capital Management Inc.\DE $309,400 0.12% 68,000
Large HRT FINANCIAL LP $307,866 0.12% 67,663
Mega BANK OF AMERICA CORP /DE/ Bank $304,918 0.12% 67,015
Small Palogic Value Management, L.P. $295,750 0.11% 65,000
Mid Brevan Howard Capital Management LP $278,974 0.11% 61,313
Mega JANE STREET GROUP, LLC $197,470 0.08% 43,400
Large Empowered Funds, LLC $191,395 0.07% 42,065
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $191,395 0.07% 42,065
Mid MANGROVE PARTNERS IM, LLC $189,812 0.07% 41,717
Large OMERS ADMINISTRATION Corp $189,280 0.07% 41,600
Mega MORGAN STANLEY $179,823 0.07% 39,522
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $159,250 0.06% 35,000
Large CAPTRUST FINANCIAL ADVISORS $145,600 0.06% 32,000
Mid Tower Research Capital LLC (TRC) $130,771 0.05% 28,741
Small nVerses Capital, LLC $129,966 0.05% 28,564
Mega Vanguard Global Advisers, LLC $101,123 0.04% 22,225
Micro Miller Financial Services LLC $100,100 0.04% 22,000
Mega RAYMOND JAMES FINANCIAL INC $88,761 0.03% 19,508
Small Persistent Asset Partners Ltd $81,531 0.03% 17,919
Mid XTX Topco Ltd $76,003 0.03% 16,704
Large NewEdge Advisors, LLC $74,456 0.03% 16,364
Small JAMES INVESTMENT RESEARCH, INC. $74,456 0.03% 16,364
Small Bedel Financial Consulting, Inc. $68,250 0.03% 15,000
Mid KESTRA PRIVATE WEALTH SERVICES, LLC $58,240 0.02% 12,800
Large BLAIR WILLIAM & CO/IL $56,720 0.02% 12,466
Small Stokes Family Office, LLC Family Office $55,146 0.02% 12,120
Small SANDERS MORRIS HARRIS LLC $54,600 0.02% 12,000
Small First City Capital Management, Inc. $53,853 0.02% 11,836
Mid GROUP ONE TRADING LLC $48,202 0.02% 10,594
Small Annandale Capital, LLC $45,500 0.02% 10,000
Micro Reliant Investment Partners, LLC $45,500 0.02% 10,000
Small Hilton Head Capital Partners, LLC $20,347 0.01% 4,472
Mega WELLS FARGO & COMPANY/MN $17,221 0.01% 3,785
Mid Farther Finance Advisors, LLC $10,465 0.00% 2,300
Large OSAIC HOLDINGS, INC. $10,010 0.00% 2,200
Large NATIONAL BANK OF CANADA /FI/ Bank $9,163 0.00% 2,014
Mega BARCLAYS PLC $8,645 0.00% 1,900
Mid SBI Securities Co., Ltd. Broker-Dealer $2,411 0.00% 530
Mid INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC $2,370 0.00% 521
Mega FMR LLC $36 0.00% 8
Mid Allworth Financial LP $22 0.00% 5
Mega ROYAL BANK OF CANADA Bank $22 0.00% 5
Key facts CIK 1228627 CUSIP 67577R102 Visit website Investor relations

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