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IRD · Opus Genetics, Inc.

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$4.27 +0.34 (+8.65%) At close · Nov 4
Market Cap
$326.96M
Shares
83.20M
Volume · Nov 4 1.16M Avg daily vol (3M) 2.48M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$4.27 Open$4.05 Day$3.98–4.32 52W close$1.74–6.07 Avg vol 30d1.5M Short int13.3M · 16.0% of shares · 7.4d Short vol53% Last earningsNov 13, 2023 DataJan 2020–Nov 2026 Filing10-Q · Aug 6

Latest documents

2026
Oct 21
Current report 8-K Events of Oct 19
Director or officer change, or executive pay

Opus Genetics, Inc. and Ashwath Jayagopal agreed that Jayagopal will transition from Chief Scientific and Development Officer effective October 19, 2026 and provide six months of consulting services at $250 per hour; his vested options will remain exercisable during the arrangement.

Oct 20
Investor event
Chardan Annual Healthcare Conference

Opus Genetics expects a $10 million milestone this quarter following FDA approval of a Viatris-partnered presbyopia eye drop, with runway into 2029. Its LCA5 trial is dosing, while another trial enrolled 11 patients.

Oct 15
Current report 8-K Events of Oct 14
Regulation FD disclosure

Opus Genetics reported improved retinal sensitivity in three of four evaluable OPGx-BEST1 participants (75%), sustained OPGx-LCA5 visual improvements through 24 months in adults, and expects Phase 3 OPGx-LCA5 dosing in the fourth quarter of 2026.

All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$9.86M
Trailing 12 months
Net income (TTM)
−$107.61M
Trailing 12 months
Revenue growth YoY
-73.8%
Year over year
Operating margin
-513.5%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
—
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$53.53M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+75.8%
Year over year · more shares
Price change (1Y)
+83.6%
Trailing year
Short interest
16.0%
Latest settlement · 7.4 days to cover
View all 122 metrics

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Buy Momentum Weak Sentiment Neutral Fundamentals Strong Quant / Vol Very High
Market backdrop VIX 20.8 · elevated Equity put/call 0.60
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg +1%
above
Price vs 50-day avg −4%
below
RSI (14) 55
neutral
MACD trend Positive
52-week position 58%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Weak
1-month return −3%
trailing
6-month return −14%
trailing
YTD return +112%
this year
Relative strength −17%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $4 › 200d $4 — 50d above 200d
Institutional flow Accumulating
23 of 103 funds reported for Sep 30 · net +29.3K sh shares · +8 new
Insider flow Distributing
Net -$3.1M over 90 days · 100% sells
Short interest Rising
16.03% of shares out · ▲ +2.5% MoM · 7.4 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
103 holders — near 3-yr high, broad support
Squeeze score 69
elevated · 0–100
Fundamentals
Strong
EPS growth +63%
Y/Y
Free cash flow $-35.3M
Buyback $50.0M
authorized
Balance sheet $44.0M
net cash
Quant / Vol
risk profile
Very High
Volatility 81%
annualized · 1-yr
Max drawdown −49%
past year
ATR 7.5%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Buy
0 · 5 · 2
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+1% Bullish
Price vs 50-day avg
−4% Neutral
RSI (14)
55 Neutral
MACD trend
Positive Bullish
52-week position
58% Neutral
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $4 › 200d $4 — 50d above 200d
Institutional flow Accumulating
23 of 103 funds reported for Sep 30 · net +29.3K sh shares · +8 new
Insider flow Distributing
Net -$3.1M over 90 days · 100% sells
Short interest Rising
16.03% of shares out · ▲ +2.5% MoM · 7.4 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
103 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $2 Now $4 · 58% Range high $6
vs 200-day avg +1% vs 50-day avg -4%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
IRD
Opus Genetics, Inc.
this stock
$326.96M +112.4% +29.1% — 16.0%
VRTX
Vertex Pharmaceuticals Inc
$139.20B +21.1% +46.2% 35.4 1.7%
REGN
Regeneron Pharmaceuticals, Inc.
$98.29B +20.6% +20.8% 21.0 2.1%
MRNA
Moderna, Inc.
$91.20B +776.2% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.49B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
107
% held
69.2%
Reported
23 of 103
Top holder
Caligan Partners LP
Held Float
View
Held by Funds
Fund positions
70
View
Short & Settlement
Short Interest Rising
Shares short
13.3M
Days to cover
7.4d
Change
+324.7K sh
View
Short Volume
Short vol %
53%
As of
Nov 4, 2026
Short Total
View
Fails to Deliver
FTD shares
4.7K
Value
$23.1K
As of
Sep 30, 2026
View
Off-Exchange
Off-exchange %
45.6%
Week of
Sep 28, 2026
Off-exch Lit
View
Smart Money
Insider Trades Net selling
Net (90d)
-$3.1M
Buyers / Sellers
0 / 5
Buyers Sellers
View
Financials
Financials
Revenue (FY)
$14.2M
Net income (FY)
$-49.6M
EPS diluted
$-0.80
View
Buybacks
Authorized
$50.0M
View
Filings
SEC Filings
Latest
8-K
Filed
Oct 21, 2026
This year
30

Opus Genetics, Inc. and Ashwath Jayagopal agreed that Jayagopal will transition from Chief Scientific and Development Officer effective October 19, 2026 and provide six months of consulting services at $250 per hour; his vested options will remain exercisable during the arrangement.

View
Proposed Sales
Value
$110.2K
Shares
28.3K
Filed
Nov 3, 2026
View
Exempt Offerings
Offering
$25.8M
Filed
Nov 7, 2024
View
Earnings & Events
Webcasts
Last webcast
Oct 20, 2026
View
Investor Relations
Latest news
Opus Genetics Presents Positive C…
Published
Oct 15, 2026
View

Performance

5D 20D 120D MTD YTD
IRD +16.0% -3.2% -14.1% +16.4% +112.4%
SPY -0.7% -1.3% +2.5% +1.5% +12.5%
vs SPY +16.7% -1.8% -16.6% +14.9% +100.0%

Capital returns

Buyback program · as of Aug 10, 2023
Authorized
$50.00M
Spent (derived)
—
Remaining
—

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1228627 CUSIP 67577R102 13F (30d) 19 filings 19 filers Visit website Investor relations