MILLENNIUM MANAGEMENT LLC

Position in IRD — Opus Genetics, Inc.

CIK 1273087 NEW YORK, NY

Position in IRD

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$9,461,635

-$2,506,830 QoQ

Shares Held

2,302,101

-12.5% QoQ

Ownership

2.77%

of shares outstanding

% of Portfolio

0.01%

of 13F equity value

Holder Rank

#10

of 102 holders

Holding Since

Mar 2021

12 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

MILLENNIUM MANAGEMENT LLC holds $4,596,705,485 across 322 Biotechnology names. IRD ranks #115 (0.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	468,410	$232,673,299
2	INSM	INSMED Inc	2,048,005	$218,358,293
3	APGE	Apogee Therapeutics, Inc.	1,491,404	$197,954,052
4	JAZZ	Jazz Pharmaceuticals plc	763,880	$184,072,163
5	ONC	BeOne Medicines Ltd.	543,323	$154,830,755
6	AXSM	Axsome Therapeutics, Inc.	556,088	$136,113,659
7	BMRN	Biomarin Pharmaceutical Inc	2,071,816	$118,549,311
8	REGN	Regeneron Pharmaceuticals, Inc.	165,120	$102,958,924

12 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$9,461,635	2,302,101	-12.5%	Shares	Sole	2026-08-14
2026-03-31	$11,968,465	2,630,432	+31.4%	Shares	Sole	2026-05-15
2025-12-31	$4,025,125	2,002,550	+1466.4%	Shares	Sole	2026-02-17
2025-06-30	$120,173	127,844	+966.2%	Shares	Sole	2025-08-14
2024-12-31	$14,269	11,991	-67.3%	Shares	Sole	2025-02-14
2024-03-31	$73,622	36,628	-57.3%	Shares	Sole	2024-05-15
2023-12-31	$258,456	85,866	+251.0%	Shares	Sole	2024-02-14
2022-09-30	$49,170	24,463	-31.2%	Shares	Sole	2022-11-14
2022-06-30	$68,317	35,582	-25.0%	Shares	Sole	2022-08-15
2021-12-31	$176,917	47,431	+79.5%	Shares	Sole	2022-02-14
2021-09-30	$136,099	26,427	+108.2%	Shares	Sole	2021-11-15
2021-03-31	$73,740	12,692	—	Shares	Sole	2021-05-17
No filing history on record for this holder in this stock.