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  • UPB Upstream Bio, Inc.

UPB

Upstream Bio, Inc.

Company with tickers: UPB

CIK
2022626
CUSIP
91678A107
Shares Outstanding
54,419,986
Price Holdings Short Volume Short Interest Fails to Deliver SEC Filings Earnings Calls Insider Trading Congress Trades
Report Date:
Holders: 133
Total Value: $1,324,396,363
Total Shares: 48,780,716
Showing top 100 of 133 holders by value
Holder Value (USD) Shares Action
FMR LLC $204,119,182 7,518,202 View
ORBIMED ADVISORS LLC $154,580,941 5,693,589 View
BlackRock, Inc. $90,803,279 3,344,504 View
Decheng Capital LLC $85,334,567 3,143,078 View
NORGES BANK $78,263,866 2,882,647 View
Enavate Sciences GP, LLC $66,780,936 2,459,703 View
UBS Group AG $49,039,496 1,806,243 View
JANUS HENDERSON GROUP PLC $41,484,059 1,527,958 View
Altshuler Shaham Ltd $36,422,811 1,341,540 View
Bain Capital Life Sciences Investors, LLC $36,097,119 1,329,544 View
Omega Fund Management, LLC $36,008,854 1,326,293 View
STATE STREET CORP $35,816,985 1,319,226 View
VR Adviser, LLC $31,746,440 1,169,298 View
WELLINGTON MANAGEMENT GROUP LLP $24,292,000 894,733 View
GEODE CAPITAL MANAGEMENT, LLC $23,129,301 851,908 View
Parkman Healthcare Partners LLC $22,658,276 834,559 View
Pictet Asset Management Holding SA $20,990,968 773,148 View
Woodline Partners LP $20,640,841 760,252 View
Integral Health Asset Management, LLC $20,362,500 750,000 View
TCG Crossover Management, LLC $20,196,504 743,886 View
Samsara BioCapital, LLC $19,983,676 736,047 View
Vestal Point Capital, LP $19,548,000 720,000 View
Siren, L.L.C. $15,976,417 588,450 View
BARCLAYS PLC $14,240,147 524,499 View
MILLENNIUM MANAGEMENT LLC $14,043,717 517,264 View
Nantahala Capital Management, LLC $13,438,462 494,971 View
MARSHALL WACE, LLP $9,333,925 343,791 View
GOLDMAN SACHS GROUP INC $9,054,009 333,481 View
GREAT POINT PARTNERS LLC $8,145,000 300,000 View
Alyeska Investment Group, L.P. $8,099,632 298,329 View
JENNISON ASSOCIATES LLC $7,842,196 288,847 View
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $7,735,876 284,931 View
NORTHERN TRUST CORP $6,429,091 236,799 View
Squadron Capital Management LLC $6,262,147 230,650 View
Invesco Ltd. $4,430,498 163,186 View
Boxer Capital Management, LLC $4,072,500 150,000 View
DEUTSCHE BANK AG\ $3,470,177 127,815 View
SummitTX Capital, L.P. $3,169,056 116,724 View
Schonfeld Strategic Advisors LLC $3,144,160 115,807 View
JPMORGAN CHASE & CO $2,994,100 110,280 View
AMERICAN CENTURY COMPANIES INC $2,382,575 87,756 View
BANK OF AMERICA CORP /DE/ $2,345,324 86,384 View
Bank of New York Mellon Corp $2,303,757 84,853 View
Nuveen, LLC $2,133,121 78,568 View
ExodusPoint Capital Management, LP $2,047,164 75,402 View
Artia Global Partners LP $1,863,928 68,653 View
Exome Asset Management LLC $1,760,541 64,845 View
AMERIPRISE FINANCIAL INC $1,535,522 56,557 View
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,516,083 55,841 View
SEVEN GRAND MANAGERS, LLC $1,357,500 50,000 View
Y-Intercept (Hong Kong) Ltd $1,264,076 46,559 View
ALPS ADVISORS INC $1,204,808 44,376 View
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,181,025 43,500 View
RHUMBLINE ADVISERS $1,127,349 41,523 View
Rafferty Asset Management, LLC $1,050,243 38,683 View
WELLS FARGO & COMPANY/MN $998,957 36,794 View
Trexquant Investment LP $842,980 31,049 View
ALLIANCEBERNSTEIN L.P. $841,921 31,010 View
AQR CAPITAL MANAGEMENT LLC $828,153 30,503 View
MORGAN STANLEY $763,512 28,122 View
D. E. Shaw & Co., Inc. $735,520 27,091 View
Swiss National Bank $722,190 26,600 View
DIADEMA PARTNERS LP $556,575 20,500 View
MetLife Investment Management, LLC $534,257 19,678 View
PRICE T ROWE ASSOCIATES INC /MD/ $533,117 19,636 View
PSP Research LLC $478,763 17,634 View
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $474,880 17,491 View
PRELUDE CAPITAL MANAGEMENT, LLC $449,604 16,560 View
SUSQUEHANNA INTERNATIONAL GROUP, LLP $447,975 16,500 View
RENAISSANCE TECHNOLOGIES LLC $445,260 16,400 View
Quantinno Capital Management LP $418,517 15,415 View
XTX Topco Ltd $409,720 15,091 View
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $397,801 14,652 View
PROFUND ADVISORS LLC $395,901 14,582 View
Graham Capital Management, L.P. $372,280 13,712 View
Legal & General Group Plc $372,198 13,709 View
CITADEL ADVISORS LLC $364,353 13,420 View
DNB Asset Management AS $347,329 12,793 View
Virtu Financial LLC $332,478 12,246 View
Verition Fund Management LLC $326,343 12,020 View
Mariner, LLC $321,184 11,830 View
Creative Planning $318,985 11,749 View
NEW YORK STATE COMMON RETIREMENT FUND $317,655 11,700 View
TWO SIGMA INVESTMENTS, LP $285,075 10,500 View
INTECH INVESTMENT MANAGEMENT LLC $282,251 10,396 View
MANUFACTURERS LIFE INSURANCE COMPANY, THE $275,491 10,147 View
CITADEL ADVISORS LLC $271,500 10,000 View
Virtus Investment Advisers, Inc. $266,097 9,801 View
STRS OHIO $266,070 9,800 View
Point72 Asset Management, L.P. $263,355 9,700 View
VARCOV Co. $261,155 9,619 View
Police & Firemen's Retirement System of New Jersey $256,730 9,456 View
VANGUARD GROUP INC $251,137 9,250 View
Persistent Asset Partners Ltd $241,824 8,907 View
China Universal Asset Management Co., Ltd. $239,082 8,806 View
ProShare Advisors LLC $226,811 8,354 View
SEI INVESTMENTS CO $219,562 8,087 View
CITIGROUP INC $188,665 6,949 View
SG Americas Securities, LLC $149,813 5,518 View
BNP PARIBAS ARBITRAGE, SA $135,098 4,976 View

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