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ORBIMED ADVISORS LLC

Position in UPB — Upstream Bio, Inc.

CIK 1055951 New York, NY

Position in UPB

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$39,399,635
-$11,842,666 QoQ
Shares Held
5,693,589
0.0% QoQ
Ownership
10.4%
of shares outstanding
% of Portfolio
0.78%
of 13F equity value
Holder Rank
#2
of 148 holders
Holding Since
Dec 2024
7 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in UPB Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

ORBIMED ADVISORS LLC holds $3,639,640,835 across 90 Biotechnology names. UPB ranks #26 (1.1% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in UPB

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7 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $39,399,635 5,693,589
2026-03-31 $51,242,301 5,693,589
2025-12-31 $154,580,941 5,693,589
2025-09-30 $107,096,409 5,693,589
2025-06-30 $62,515,607 5,693,589
2025-03-31 $34,844,764 5,693,589
2024-12-31 $93,602,603 5,693,589