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D. E. Shaw & Co., Inc.

Position in UPB — Upstream Bio, Inc.

CIK 1009207 New York, NY

Position in UPB

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$7,169,423
-$214,897 QoQ
Shares Held
1,036,044
+26.3% QoQ
Ownership
1.89%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#9
of 148 holders
Holding Since
Dec 2025
3 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in UPB Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

D. E. Shaw & Co., Inc. holds $5,139,216,221 across 216 Biotechnology names. UPB ranks #86 (0.1% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in UPB

Export CSV
3 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $7,169,423 1,036,044
2026-03-31 $7,384,320 820,480
2025-12-31 $735,520 27,091