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Equibles

D. E. Shaw & Co., Inc.

Position in INSM — INSMED Inc

CIK 1009207 New York, NY
Back to INSM Full portfolio

Position in INSM

as of Mar 31, 2026 · filed May 15, 2026
Position Value
$919,934,903
+$162,687,735 QoQ
Shares Held
5,625,825
+29.3% QoQ
Ownership
2.60%
of shares outstanding
% of Portfolio
0.81%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority Sole 99.91793203663462.ToString("F0")% Shared 0.ToString("F0")% None 0.08206796336537307.ToString("F0")%

Common Shares in INSM Over Time

Shares Held

Position Value (USD)

Derivatives in INSM

reported options exposure · as of Mar 31, 2026
CallValue
$1,864,128
CallShares
11,400
PutValue
$899,360
PutShares
5,500

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

D. E. Shaw & Co., Inc. holds $4,371,472,260 across 180 Biotechnology names. INSM ranks #1 (21.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 INSM
INSMED Inc
This page 		5,625,825 $919,934,903
2 ALNY
Alnylam Pharmaceuticals, Inc.
 1,059,062 $350,411,843
3 BBIO
BridgeBio Pharma, Inc.
 2,545,486 $189,027,789
4 PCVX
Vaxcyte, Inc.
 2,865,318 $166,503,628
5 EXEL
Exelixis, Inc.
 3,603,063 $154,535,371
6 HALO
Halozyme Therapeutics, Inc.
 1,868,708 $120,774,597
7 PTCT
Ptc Therapeutics, Inc.
 1,640,381 $111,759,157
8 VRTX
Vertex Pharmaceuticals Inc / Ma
 248,960 $111,170,598

All Filings in INSM

Export CSV
35 filing rows on record
Report Date Value (USD) Shares
2026-03-31 $919,934,903 5,625,825
2026-03-31 $899,360 5,500
2026-03-31 $1,864,128 11,400
2025-12-31 $757,247,168 4,350,995
2025-12-31 $2,105,884 12,100
2025-12-31 $278,464 1,600
2025-09-30 $814,731,390 5,657,464
2025-09-30 $8,885,417 61,700
2025-09-30 $1,440,100 10,000
2025-06-30 $1,006,400 10,000
2025-06-30 $344,452,375 3,422,619
2025-03-31 $762,900 10,000
2025-03-31 $56,063,994 734,880
2024-12-31 $35,126,654 508,787
2024-12-31 $690,400 10,000
2024-09-30 $730,000 10,000
2024-09-30 $4,871,655 66,735
2024-06-30 $19,332,917 288,551
2024-03-31 $4,721,216 174,022
2023-12-31 $20,047,646 646,907
2023-09-30 $4,967,356 196,727
2023-06-30 $2,086,874 98,904
2023-03-31 $4,047,107 237,367
2022-12-31 $8,537,114 427,283
2022-09-30 $13,720,829 636,993
2022-06-30 $7,388,019 374,646
2022-03-31 $6,955,835 295,993
2021-12-31 $8,273,605 303,730
2021-09-30 $10,024,119 363,984
2021-06-30 $12,042,735 423,146
2021-03-31 $25,538,494 749,809
2020-12-31 $33,373,124 1,002,497
2020-09-30 $51,907,706 1,615,050
2020-06-30 $48,131,850 1,747,707
2020-03-31 $35,856,672 2,236,848

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