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Equibles

D. E. Shaw & Co., Inc.

Position in VRTX — Vertex Pharmaceuticals Inc / Ma

CIK 1009207 New York, NY
Back to VRTX Full portfolio

Position in VRTX

as of Mar 31, 2026 · filed May 15, 2026
Position Value
$111,170,598
+$111,170,598 QoQ
Shares Held
248,960
Ownership
0.098%
of shares outstanding
% of Portfolio
0.10%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in VRTX Over Time

Shares Held

Position Value (USD)

Derivatives in VRTX

reported options exposure · as of Dec 31, 2025
CallValue
$15,006,216
CallShares
33,100
PutValue
$4,261,584
PutShares
9,400

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

D. E. Shaw & Co., Inc. holds $4,382,181,531 across 180 Biotechnology names. VRTX ranks #8 (2.5% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 INSM
INSMED Inc
 5,625,825 $919,934,903
2 ALNY
Alnylam Pharmaceuticals, Inc.
 1,059,062 $350,411,843
3 BBIO
BridgeBio Pharma, Inc.
 2,545,486 $189,027,789
4 PCVX
Vaxcyte, Inc.
 2,865,318 $166,503,628
5 EXEL
Exelixis, Inc.
 3,603,063 $154,535,371
6 HALO
Halozyme Therapeutics, Inc.
 1,868,708 $120,774,597
7 PTCT
Ptc Therapeutics, Inc.
 1,640,381 $111,759,157
8 VRTX
Vertex Pharmaceuticals Inc / Ma
This page 		248,960 $111,170,598

All Filings in VRTX

Export CSV
48 filing rows on record
Report Date Value (USD) Shares
2026-03-31 $111,170,598 248,960
2025-12-31 $4,261,584 9,400
2025-12-31 $15,006,216 33,100
2025-09-30 $1,309,251 3,343
2025-09-30 $4,856,336 12,400
2025-09-30 $13,942,384 35,600
2025-06-30 $2,226,000 5,000
2025-06-30 $8,940,060 20,081
2025-06-30 $1,602,720 3,600
2025-03-31 $6,205,696 12,800
2025-03-31 $34,874,556 71,933
2025-03-31 $1,066,604 2,200
2024-12-31 $106,990,946 265,684
2024-09-30 $6,557,628 14,100
2024-09-30 $64,370,792 138,408
2024-06-30 $2,343,600 5,000
2024-06-30 $79,711,928 170,063
2024-03-31 $3,720,289 8,900
2024-03-31 $148,584,998 355,458
2023-12-31 $86,659,838 212,981
2023-09-30 $486,836 1,400
2023-09-30 $89,366,745 256,993
2023-06-30 $88,596,157 251,758
2023-03-31 $64,567,925 204,932
2022-12-31 $31,919,719 110,533
2022-12-31 $2,310,240 8,000
2022-09-30 $2,316,320 8,000
2022-09-30 $34,238,973 118,253
2022-06-30 $5,072,220 18,000
2022-06-30 $78,547,271 278,744
2022-03-31 $5,323,788 20,400
2022-03-31 $194,226,399 744,248
2021-12-31 $224,282,530 1,021,323
2021-12-31 $11,177,640 50,900
2021-09-30 $311,017,460 1,714,634
2021-09-30 $17,993,888 99,200
2021-06-30 $156,669,533 777,015
2021-06-30 $11,896,170 59,000
2021-03-31 $117,464,031 546,624
2021-03-31 $5,157,360 24,000
2020-12-31 $206,643,406 874,348
2020-12-31 $3,285,126 13,900
2020-09-30 $3,782,468 13,900
2020-09-30 $95,551,672 351,138
2020-06-30 $42,916,526 147,830
2020-06-30 $4,209,495 14,500
2020-03-31 $3,569,250 15,000
2020-03-31 $70,715,645 297,187

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