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Equibles

D. E. Shaw & Co., Inc.

Position in AXSM — Axsome Therapeutics, Inc.

CIK 1009207 New York, NY
Back to AXSM Full portfolio

Position in AXSM

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$148,025,391
+$46,027,738 QoQ
Shares Held
604,753
+0.2% QoQ
Ownership
1.15%
of shares outstanding
% of Portfolio
0.10%
of 13F equity value
Holder Rank
#15
of 494 holders
Holding Since
Mar 2020
25 quarters on record
Voting authority Sole 99% Shared 0% None 1%

Common Shares in AXSM Over Time

Shares Held

Position Value (USD)

Derivatives in AXSM

reported options exposure · as of Jun 30, 2026
CallValue
$2,105,022
CallShares
8,600
PutValue
$9,790,800
PutShares
40,000

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

D. E. Shaw & Co., Inc. holds $5,016,183,849 across 217 Biotechnology names. AXSM ranks #7 (3.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 INSM
INSMED Inc
 5,877,959 $626,707,987
2 ALNY
Alnylam Pharmaceuticals, Inc.
 1,104,109 $332,369,932
3 EXEL
Exelixis, Inc.
 5,551,747 $302,070,554
4 BBIO
BridgeBio Pharma, Inc.
 3,633,007 $270,586,360
5 TGTX
Tg Therapeutics, Inc.
 3,400,808 $186,840,390
6 HALO
Halozyme Therapeutics, Inc.
 2,006,479 $157,047,110
7 AXSM
Axsome Therapeutics, Inc.
This page 		604,753 $148,025,391
8 PTCT
Ptc Therapeutics, Inc.
 1,548,919 $126,345,322

All Filings in AXSM

Export CSV
50 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $9,790,800 40,000
2026-06-30 $148,025,391 604,753
2026-06-30 $2,105,022 8,600
2026-03-31 $101,997,653 603,465
2026-03-31 $625,374 3,700
2025-12-31 $100,289,997 549,113
2025-12-31 $1,588,968 8,700
2025-09-30 $801,570 6,600
2025-09-30 $35,984,055 296,287
2025-06-30 $688,974 6,600
2025-06-30 $20,957,753 200,764
2025-03-31 $63,874,168 547,665
2025-03-31 $769,758 6,600
2024-12-31 $1,721,475 20,346
2024-12-31 $2,665,215 31,500
2024-12-31 $2,056,023 24,300
2024-09-30 $1,375,011 15,300
2024-09-30 $260,623 2,900
2024-09-30 $2,830,905 31,500
2024-06-30 $821,100 10,200
2024-06-30 $2,535,750 31,500
2024-06-30 $509,887 6,334
2024-03-31 $813,960 10,200
2024-03-31 $619,966 7,769
2024-03-31 $2,513,700 31,500
2023-12-31 $2,753,814 34,600
2023-12-31 $730,954 9,184
2023-09-30 $2,418,194 34,600
2023-06-30 $2,486,356 34,600
2023-03-31 $1,887,408 30,600
2022-12-31 $771,300 10,000
2022-06-30 $258,984 6,762
2022-03-31 $6,431,674 155,392
2021-12-31 $3,400,200 90,000
2021-09-30 $459,429 13,939
2021-09-30 $988,800 30,000
2021-06-30 $2,023,800 30,000
2021-06-30 $1,403,168 20,800
2021-06-30 $1,554,885 23,049
2021-03-31 $1,698,600 30,000
2021-03-31 $1,880,803 33,218
2021-03-31 $1,177,696 20,800
2020-12-31 $13,620,317 167,182
2020-12-31 $1,694,576 20,800
2020-12-31 $2,444,100 30,000
2020-09-30 $16,475,992 231,242
2020-09-30 $2,137,500 30,000
2020-09-30 $1,482,000 20,800
2020-06-30 $19,393,641 235,703
2020-06-30 $2,468,400 30,000

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