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Equibles

DIMENSIONAL FUND ADVISORS LP

Position in UPB — Upstream Bio, Inc.

CIK 354204 AUSTIN, TX
Back to UPB Full portfolio

Position in UPB

as of Jun 30, 2026 · filed Aug 11, 2026
Position Value
$2,640,761
+$1,920,743 QoQ
Shares Held
381,613
+377.0% QoQ
Ownership
0.697%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#27
of 148 holders
Holding Since
Mar 2026
2 quarters on record
Voting authority Sole 85% Shared 11% None 4%

Common Shares in UPB Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

DIMENSIONAL FUND ADVISORS LP holds $6,163,799,259 across 230 Biotechnology names. UPB ranks #129 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 VRTX
Vertex Pharmaceuticals Inc / Ma
 1,168,956 $580,655,511
2 JAZZ
Jazz Pharmaceuticals plc
 1,713,592 $412,924,262
3 REGN
Regeneron Pharmaceuticals, Inc.
 559,687 $348,987,230
4 INCY
Incyte Corp
 2,280,803 $258,551,825
5 EXEL
Exelixis, Inc.
 4,426,620 $240,852,392
6 BMRN
Biomarin Pharmaceutical Inc
 4,075,714 $233,212,353
7 ROIV
Roivant Sciences Ltd.
 5,230,417 $185,104,455
8 KRYS
Krystal Biotech, Inc.
 476,038 $176,929,041

All Filings in UPB

Export CSV
2 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $2,640,761 381,613
2026-03-31 $720,018 80,002