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Equibles

JANE STREET GROUP, LLC

Position in UPB — Upstream Bio, Inc.

CIK 1595888 NEW YORK, NY
Back to UPB Full portfolio

Position in UPB

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$107,910
+$107,910 QoQ
Shares Held
15,594
Ownership
0.028%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#98
of 148 holders
Holding Since
Dec 2024
4 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in UPB Over Time

Shares Held

Position Value (USD)

Derivatives in UPB

reported options exposure · as of Jun 30, 2026
CallValue
$82,348
CallShares
11,900
PutValue
$0
PutShares
0

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,372,861,470 across 292 Biotechnology names. UPB ranks #197 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 BBIO
BridgeBio Pharma, Inc.
 2,934,193 $218,538,693
2 MDGL
Madrigal Pharmaceuticals, Inc.
 191,541 $102,847,939
3 AXSM
Axsome Therapeutics, Inc.
 403,995 $98,885,855
4 TGTX
Tg Therapeutics, Inc.
 1,752,646 $96,290,370
5 EXEL
Exelixis, Inc.
 1,402,438 $76,306,651
6 QURE
uniQure N.V.
 1,610,483 $74,178,846
7 HALO
Halozyme Therapeutics, Inc.
 694,684 $54,372,915
8 TVTX
Travere Therapeutics, Inc.
 938,699 $53,327,489

All Filings in UPB

Export CSV
5 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $82,348 11,900
2026-06-30 $107,910 15,594
2026-03-31 $137,700 15,300
2025-09-30 $385,605 20,500
2024-12-31 $748,825 45,549