JANE STREET GROUP, LLC

Position in AXSM — Axsome Therapeutics, Inc.

CIK 1595888 NEW YORK, NY

Back to AXSM Full portfolio

Position in AXSM

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$98,885,855

+$98,196,592 QoQ

Shares Held

403,995

+9806.7% QoQ

Ownership

0.771%

of shares outstanding

% of Portfolio

0.07%

of 13F equity value

Holder Rank

#26

of 494 holders

Holding Since

Mar 2020

26 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in AXSM Over Time

Shares Held

Position Value (USD)

Derivatives in AXSM

reported options exposure · as of Jun 30, 2026

CallValue

$42,859,227

CallShares

175,100

PutValue

$41,782,239

PutShares

170,700

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,363,981,840 across 291 Biotechnology names. AXSM ranks #3 (7.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	BBIO	BridgeBio Pharma, Inc.	2,934,193	$218,538,693
2	MDGL	Madrigal Pharmaceuticals, Inc.	191,541	$102,847,939
3	AXSM	Axsome Therapeutics, Inc. This page	403,995	$98,885,855
4	TGTX	Tg Therapeutics, Inc.	1,752,646	$96,290,370
5	EXEL	Exelixis, Inc.	1,402,438	$76,306,651
6	QURE	uniQure N.V.	1,610,483	$74,178,846
7	HALO	Halozyme Therapeutics, Inc.	694,684	$54,372,915
8	TVTX	Travere Therapeutics, Inc.	938,699	$53,327,489

All Filings in AXSM

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50 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$41,782,239	170,700	+106.9%	Put	Defined	2026-08-14
2026-06-30	$42,859,227	175,100	+59.6%	Call	Defined	2026-08-14
2026-06-30	$98,885,855	403,995	+9806.7%	Shares	Defined	2026-08-14
2026-03-31	$13,944,150	82,500	+50.5%	Put	Defined	2026-05-12
2026-03-31	$18,541,494	109,700	-6.7%	Call	Defined	2026-05-12
2026-03-31	$689,263	4,078	-97.0%	Shares	Defined	2026-05-12
2025-12-31	$10,008,672	54,800	+2.8%	Put	Defined	2026-02-12
2025-12-31	$21,478,464	117,600	+33.8%	Call	Defined	2026-02-12
2025-12-31	$25,073,366	137,283	+4.9%	Shares	Defined	2026-02-12
2025-09-30	$10,675,455	87,900	-28.9%	Call	Defined	2025-11-14
2025-09-30	$6,473,285	53,300	+156.2%	Put	Defined	2025-11-14
2025-09-30	$15,891,124	130,845	+45.2%	Shares	Defined	2025-11-14
2025-06-30	$2,171,312	20,800	-75.2%	Put	Defined	2025-08-14
2025-06-30	$12,913,043	123,700	-9.9%	Call	Defined	2025-08-14
2025-03-31	$10,513,144	90,141	+14.9%	Shares	Defined	2025-05-19
2025-03-31	$16,013,299	137,300	-65.3%	Call	Defined	2025-05-19
2025-03-31	$9,785,257	83,900	-47.7%	Put	Defined	2025-05-19
2024-12-31	$6,637,568	78,449	-39.7%	Shares	Defined	2025-02-14
2024-12-31	$13,571,444	160,400	+48.1%	Put	Defined	2025-02-14
2024-12-31	$33,454,794	395,400	+245.3%	Call	Defined	2025-02-14
2024-09-30	$10,290,115	114,500	+0.4%	Call	Defined	2024-11-15
2024-09-30	$9,732,921	108,300	+258.6%	Put	Defined	2024-11-15
2024-09-30	$11,691,816	130,097	-22.8%	Shares	Defined	2024-11-15
2024-06-30	$13,558,936	168,434	-15.4%	Shares	Defined	2024-08-15
2024-03-31	$15,886,504	199,079	+114.5%	Shares	Defined	2024-05-16
2023-12-31	$7,388,418	92,831	-26.1%	Shares	Defined	2024-02-15
2023-09-30	$8,776,855	125,581	-54.5%	Shares	Defined	2023-11-15
2023-06-30	$19,826,317	275,902	+1168.9%	Shares	Defined	2023-08-14
2023-03-31	$1,341,169	21,744	-87.6%	Shares	Defined	2023-05-16
2022-12-31	$13,567,089	175,899	-3.8%	Shares	Defined	2023-02-15
2022-09-30	$8,159,659	182,870	+336.5%	Shares	Defined	2022-11-15
2022-06-30	$1,604,577	41,895	+3.3%	Shares	Defined	2022-08-16
2022-03-31	$1,678,736	40,559	-89.8%	Shares	Defined	2022-05-17
2022-03-31	$4,722,599	114,100	-82.1%	Call	Defined	2022-05-17
2022-03-31	$1,249,978	30,200	-40.9%	Put	Defined	2022-05-17
2021-12-31	$15,066,436	398,794	+36.0%	Shares	Defined	2022-02-15
2021-12-31	$1,930,558	51,100	-59.1%	Put	Defined	2022-02-15
2021-12-31	$24,050,748	636,600	+105.6%	Call	Defined	2022-02-15
2021-09-30	$4,116,704	124,900	-55.2%	Put	Defined	2021-11-16
2021-09-30	$10,204,416	309,600	+762.4%	Call	Defined	2021-11-16
2021-09-30	$9,668,222	293,332	+185.6%	Shares	Defined	2021-11-16
2021-06-30	$6,928,883	102,711	+11.4%	Shares	Defined	2021-08-16
2021-06-30	$18,787,610	278,500	-23.4%	Put	Defined	2021-08-16
2021-06-30	$2,421,814	35,900	+105.1%	Call	Defined	2021-08-16
2021-03-31	$5,218,778	92,172	+27.6%	Shares	Defined	2021-05-18
2021-03-31	$990,850	17,500	-82.8%	Call	Defined	2021-05-18
2021-03-31	$20,581,370	363,500	+88.6%	Put	Defined	2021-05-18
2020-12-31	$15,699,269	192,700	—	Put	Defined	2021-02-17
2020-12-31	$5,886,532	72,254	—	Shares	Defined	2021-02-17
2020-12-31	$8,309,940	102,000	—	Call	Defined	2021-02-17
No filing history on record for this holder in this stock.