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Point72 Asset Management, L.P.

Position in UPB — Upstream Bio, Inc.

CIK 1603466 STAMFORD, CT

Position in UPB

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$3,134,836
+$1,531,324 QoQ
Shares Held
453,011
+154.3% QoQ
Ownership
0.827%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#25
of 148 holders
Holding Since
Dec 2025
3 quarters on record
Voting authority Sole 0% Shared 100% None 0%

Common Shares in UPB Over Time

Shares Held

Position Value (USD)

Derivatives in UPB

reported options exposure · as of Mar 31, 2026
CallValue
$103,500
CallShares
11,500
PutValue
$0
PutShares
0

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

Point72 Asset Management, L.P. holds $2,243,273,342 across 172 Biotechnology names. UPB ranks #88 (0.1% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in UPB

Export CSV
4 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $3,134,836 453,011
2026-03-31 $103,500 11,500
2026-03-31 $1,603,512 178,168
2025-12-31 $263,355 9,700