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UPB

Upstream Bio, Inc.

Company with tickers: UPB

CIK
2022626
CUSIP
91678A107
Shares Outstanding
54,419,986
13F Activity (30d)
13 filings 8 filers

Total shares sold short and not yet covered, reported to FINRA by broker-dealers and published twice a month (bi-monthly). Days to cover divides the short position by average daily volume; a high value (above 5) can signal short-squeeze potential.

Short Squeeze Score
66/100
Short interest 6.7% of shares — P80 Days to cover 6.8 — P83 Short-volume trend -4.2% — P36

Peer-relative percentile rank across all stocks reporting short interest at the latest settlement date (2026-05-29). Equal-weight mean of the available factors.

Short Interest History

Settlement Date Current Position Previous Position Change Days to Cover
2026-05-29 3,640,867 3,397,759 +243,108 6.81
2026-05-15 3,397,759 3,223,622 +174,137 6.69
2026-04-30 3,223,622 3,022,894 +200,728 5.71
2026-04-15 3,022,894 3,435,261 -412,367 5.24
2026-03-31 3,435,261 4,752,354 -1,317,093 3.46
2026-03-13 4,752,354 4,086,377 +665,977 4.44
2026-02-27 4,086,377 3,529,797 +556,580 1.83
2026-02-13 3,529,797 3,183,884 +345,913 1.52
2026-01-30 3,183,884 3,451,544 -267,660 5.54
2026-01-15 3,451,544 3,486,600 -35,056 5.29
2025-12-31 3,486,600 2,983,568 +503,032 5.75
2025-12-15 2,983,568 2,773,635 +209,933 5.58
2025-11-28 2,773,635 2,994,056 -220,421 5.12
2025-11-14 2,994,056 2,929,476 +64,580 7.81
2025-10-31 2,929,476 3,336,913 -407,437 7.88
2025-10-15 3,336,913 3,564,217 -227,304 10.27
2025-09-30 3,564,217 3,011,653 +552,564 6.44
2025-09-15 3,011,653 3,097,969 -86,316 4.54
2025-08-29 3,097,969 3,160,080 -62,111 8.78
2025-08-15 3,160,080 3,080,800 +79,280 6.43
2025-07-31 3,080,800 3,781,146 -700,346 5.75
2025-07-15 3,781,146 4,109,973 -328,827 14.13
2025-06-30 4,109,973 3,610,360 +499,613 5.72
Showing 1–23 of 23 settlements