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Equibles

CITADEL ADVISORS LLC

Position in UPB — Upstream Bio, Inc.

CIK 1423053 MIAMI, FL
Back to UPB Full portfolio

Position in UPB

as of Jun 30, 2026 · filed Sep 2, 2026
Position Value
$0
+$0 QoQ
Shares Held
0
Ownership
0.000%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Dec 2024
5 quarters on record

Common Shares in UPB Over Time

Shares Held

Position Value (USD)

Derivatives in UPB

reported options exposure · as of Jun 30, 2026
CallValue
$103,800
CallShares
15,000
PutValue
$0
PutShares
0

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

CITADEL ADVISORS LLC holds $6,150,763,744 across 435 Biotechnology names.

# Ticker Company Shares Value (USD) Open
1 ONC
BeOne Medicines Ltd.
 1,425,517 $406,229,578
2 BBIO
BridgeBio Pharma, Inc.
 3,760,028 $280,046,885
3 INSM
INSMED Inc
 2,556,973 $272,624,460
4 MDGL
Madrigal Pharmaceuticals, Inc.
 507,233 $272,358,759
5 VRTX
Vertex Pharmaceuticals Inc / Ma
 510,430 $253,545,893
6 JAZZ
Jazz Pharmaceuticals plc
 1,006,676 $242,578,715
7 MANE
Veradermics, Inc
 1,877,775 $230,853,658
8 ROIV
Roivant Sciences Ltd.
 5,576,261 $197,343,876

All Filings in UPB

Export CSV
8 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $103,800 15,000
2026-03-31 $223,200 24,800
2026-03-31 $483,300 53,700
2025-12-31 $271,500 10,000
2025-12-31 $364,353 13,420
2025-09-30 $532,323 28,300
2025-09-30 $355,509 18,900
2024-12-31 $2,959,200 180,000